Zobrazeno 1 - 4
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pro vyhledávání: '"Mikel Ruterbusch"'
Publikováno v:
Annual Review of Immunology. 38:705-725
The discovery of CD4+ T cell subset–defining master transcription factors and framing of the Th1/Th2 paradigm ignited the CD4+ T cell field. Advances in in vivo experimental systems, however, have revealed that more complex lineage-defining transcr
Autor:
Lestat R. Ali, Javier Castellanos, K. Christopher Garcia, Stephanie J. Crowley, Tamara Biary, Gonçalo J. L. Bernardes, Daniel-Adriano Silva, Mikel Ruterbusch, David Baker, Isabel Leung, Carl Walkey, Brian D. Weitzner, Shawn Yu, Marion Pepper, Alfredo Quijano-Rubio, Enrique Marcos, Fátima Pardo-Avila, Umut Ulge, Lance Stewart, Kevin Jude, Stanley R. Riddell, Michael Dougan, Jamie B. Spangler, Lauren Carter, Carlos Labão-Almeida
Publikováno v:
Nature
© 2019 Springer Nature limited. All rights reserved.
We describe a de novo computational approach for designing proteins that recapitulate the binding sites of natural cytokines, but are otherwise unrelated in topology or amino acid sequence. W
We describe a de novo computational approach for designing proteins that recapitulate the binding sites of natural cytokines, but are otherwise unrelated in topology or amino acid sequence. W
Publikováno v:
Annual review of immunology. 38
The discovery of CD4
Publikováno v:
European Journal of Immunology. 48:80-86
CD4+ tissue resident cells are an important first line of defense against viral infections in the lungs and are critical for promoting the localization of lung resident CD8+ T cells. However, relatively little is known about the signaling programs re