Zobrazeno 1 - 10
of 303
pro vyhledávání: '"Mike West"'
Publikováno v:
Journal of Virus Eradication, Vol 4, Iss , Pp 16- (2018)
Externí odkaz:
https://doaj.org/article/eb80a91922d041279974b85d5ca5520d
Publikováno v:
Molecular Systems Biology, Vol 7, Iss 1, Pp 1-10 (2011)
Abstract Precise control of cell proliferation is fundamental to tissue homeostasis and differentiation. Mammalian cells commit to proliferation at the restriction point (R‐point). It has long been recognized that the R‐point is tightly regulated
Externí odkaz:
https://doaj.org/article/3ff0caf2b9304ff898d66be15d90522a
Autor:
Mike West
Publikováno v:
World Review of Political Economy, Vol 1, Iss 3, Pp 531-539 (2010)
Externí odkaz:
https://doaj.org/article/cd55d175e2a84ae4b68ee4bcbaddb353
Autor:
Andrew Cron, Cécile Gouttefangeas, Jacob Frelinger, Lin Lin, Satwinder K Singh, Cedrik M Britten, Marij J P Welters, Sjoerd H van der Burg, Mike West, Cliburn Chan
Publikováno v:
PLoS Computational Biology, Vol 9, Iss 7, p e1003130 (2013)
Flow cytometry is the prototypical assay for multi-parameter single cell analysis, and is essential in vaccine and biomarker research for the enumeration of antigen-specific lymphocytes that are often found in extremely low frequencies (0.1% or less)
Externí odkaz:
https://doaj.org/article/06513624c96542608300c537b0a8b6af
Publikováno v:
PLoS Computational Biology, Vol 7, Iss 10, p e1002209 (2011)
Cellular processes are "noisy". In each cell, concentrations of molecules are subject to random fluctuations due to the small numbers of these molecules and to environmental perturbations. While noise varies with time, it is often measured at steady
Externí odkaz:
https://doaj.org/article/4b78f5e89dda481489c277f75ef45c5e
Autor:
Julia Ling-Yu Chen, Daniel Merl, Christopher W Peterson, Jianli Wu, Patrick Yantyng Liu, Hanwei Yin, Deborah M Muoio, Don E Ayer, Mike West, Jen-Tsan Chi
Publikováno v:
PLoS Genetics, Vol 6, Iss 9, p e1001093 (2010)
Although lactic acidosis is a prominent feature of solid tumors, we still have limited understanding of the mechanisms by which lactic acidosis influences metabolic phenotypes of cancer cells. We compared global transcriptional responses of breast ca
Externí odkaz:
https://doaj.org/article/63b1b63381834dcca4325d2a5db10c33
Publikováno v:
PLoS ONE, Vol 4, Iss 2, p e4523 (2009)
Human disease studies using DNA microarrays in both clinical/observational and experimental/controlled studies are having increasing impact on our understanding of the complexity of human diseases. A fundamental concept is the use of gene expression
Externí odkaz:
https://doaj.org/article/2fa62723eb1d4f3fa41187d92a8d558f
Autor:
Julia Ling-Yu Chen, Joseph E Lucas, Thies Schroeder, Seiichi Mori, Jianli Wu, Joseph Nevins, Mark Dewhirst, Mike West, Jen-Tsan Chi
Publikováno v:
PLoS Genetics, Vol 4, Iss 12, p e1000293 (2008)
The tumor microenvironment has a significant impact on tumor development. Two important determinants in this environment are hypoxia and lactic acidosis. Although lactic acidosis has long been recognized as an important factor in cancer, relatively l
Externí odkaz:
https://doaj.org/article/23fd5bbd06b848649aaed526c6b8b8ae
Autor:
Anthony O' Hagan, Mike West
Bayesian analysis has developed rapidly in applications in the last two decades and research in Bayesian methods remains dynamic and fast-growing. Dramatic advances in modelling concepts and computational technologies now enable routine application o
Autor:
Paul N. Bennett, Clara Bohm, Angela Yee-Moon Wang, Talerngsak Kanjanabuch, Ana Elizabeth Figueiredo, Oksana Harasemiw, Leanne Brown, Iwona Gabrys, Dev Jegatheesan, Kelly Lambert, Courtney J. Lightfoot, Jennifer MacRae, Nicole Scholes-Robertson, Krista Stewart, Brett Tarca, Nancy Verdin, Madeleine Warren, Mike West, Deborah Zimmerman, Jeannette Finderup, Emilie Ford, Heitor S. Ribeiro, Qunyan Xu, Stephanie Thompson
Publikováno v:
Kidney International Reports.
Refereed/Peer-reviewed Introduction: Low activity levels and poor physical function are associated with technique failure and mortality in people receiving peritoneal dialysis (PD). Adequate levels of physical function are required to maintain indepe