Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Mike VanRollins"'
Publikováno v:
Journal of Lipid Research, Vol 49, Iss 5, Pp 995-1005 (2008)
Unlike F4-neuroprostanes (F4-NeuroPs), which are relatively selective in vivo markers of oxidative damage to neuronal membranes, there currently is no method to assess the extent of free radical damage to myelin with relative selectively. The polyuns
Externí odkaz:
https://doaj.org/article/e25e8d686c68469296eb0e740880fffa
Publikováno v:
Journal of Lipid Research, Vol 41, Iss 1, Pp 66-74 (2000)
Epoxyeicosatrienoic acids (EETs), the eicosanoid biomediators synthesized from arachidonic acid by cytochrome P450 epoxygenases, are inactivated in many tissues by conversion to dihydroxyeicosatrienoic acids (DHETs). However, we find that human skin
Externí odkaz:
https://doaj.org/article/dedc8b3d010f411cacfc4f4e4a5f17c5
Publikováno v:
Analytical Chemistry. 74:5859-5865
Autor:
Tong Lu, Hon Chi Lee, Arthur A. Spector, Prasad V. G. Katakam, Mike VanRollins, Neal L. Weintraub
Publikováno v:
The Journal of Physiology. 534:651-667
1. Dihydroxyeicosatrienoic acids (DHETs), which are metabolites of arachidonic acid (AA) and epoxyeicosatrienoic acids (EETs), have been identified as highly potent endogenous vasodilators, but the mechanisms by which DHETs induce relaxation of vascu
Autor:
Hon Chi Lee, Kevin C. Dellsperger, Mike VanRollins, Tong Lu, Yongde Zhang, Christine L. Oltman
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 280:H2430-H2440
Epoxyeicosatrienoic acids (EETs) are released from endothelial cells and potently dilate small arteries by hyperpolarizing vascular myocytes. In the present study, we investigated the structural specificity of EETs in dilating canine and porcine coro
Publikováno v:
Journal of Lipid Research, Vol 41, Iss 1, Pp 66-74 (2000)
Epoxyeicosatrienoic acids (EETs), the eicosanoid biomediators synthesized from arachidonic acid by cyto- chrome P450 epoxygenases, are inactivated in many tissues by conversion to dihydroxyeicosatrienoic acids (DHETs). However, we find that human ski
Publikováno v:
Circulation Research. 83:932-939
Abstract —Cytochrome P 450 epoxygenases convert arachidonic acid into 4 epoxyeicosatrienoic acid (EET) regioisomers, which were recently identified as endothelium-derived hyperpolarizing factors in coronary blood vessels. Both EETs and their dihydr
Publikováno v:
Journal of Lipid Research, Vol 39, Iss 8, Pp 1696-1704 (1998)
To minimize oxidative modification, a low tem- perature, sequential flotation method was developed to isolate plasma lipoproteins in 18 h using a benchtop ultra- centrifuge. The protein distributions were characterized using agarose and SDS-polyacryl
Publikováno v:
Circulation Research. 79:784-793
Epoxyeicosatrienoic acids (EETs) are potent vasodilators derived from cytochrome P-450 metabolism of arachidonic acid. The rapid conversion of EETs to their corresponding dihydroxyeicosatrienoic acids (DHETs) has been proposed as a process whereby EE
Publikováno v:
Journal of Lipid Research, Vol 36, Iss 6, Pp 1236-1246 (1995)
Epoxyeicosatrienoic acids (EETs) are eicosanoids synthesized from arachidonic acid by the cytochrome P450 eposygenase pathway. The present studies demonstrate that 8,9-, 11,12-, and 14,15-EET are rapidly taken up by porcine aortic smooth muscle cells