Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Mike Tobyn"'
Autor:
Nihad Mawla, Maen Alshafiee, John Gamble, Mike Tobyn, Lande Liu, Karl Walton, Barbara R. Conway, Peter Timmins, Kofi Asare-Addo
Publikováno v:
Pharmaceutics, Vol 15, Iss 8, p 2154 (2023)
Hypromellose, a widely used polymer in the pharmaceutical industry, is available in several grades, depending on the percentage of substitution of the methoxyl and hydroxypropyl groups and molecular weight, and in various functional forms (e.g., suit
Externí odkaz:
https://doaj.org/article/98c83aba074d4b6c94f6b1f40136f9c3
Autor:
Ross Blundell, Paul Butterworth, Anne Charlier, Dominick Daurio, Matthias Degenhardt, David Harris, Bruno Hancock, Megan Johnston, Ram Kasina, Jonathan Kaye, Ron Kelly, Philip Lienbacher, Liz Meehan, Jason Melnick, Peter Ojakovo, Jochen Schoell, Bernhard Schimmelle, Mike Tobyn, Leonie Wagner-Hattler, Joanne Wakeman, Raphael Wiedey
Publikováno v:
Journal of Pharmaceutical Sciences. 111:2943-2954
Titanium dioxide (in the form of E171) is a ubiquitous excipient in tablets and capsules for oral use. In the coating of a tablet or in the shell of a capsule the material disperses visible and UV light so that the contents are protected from the eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76ec62517dd921d0fe363937126b1377
https://doi.org/10.1016/j.xphs.2022.08.011
https://doi.org/10.1016/j.xphs.2022.08.011
Autor:
Andrew D. Strongrich, Mike Tobyn, Lavanya K. Iyer, Yirang Park, JiaMei Hong, Alina A. Alexeenko
Publikováno v:
Journal of pharmaceutical sciences. 112(1)
Quality control is of critical importance in manufacturing of lyophilized drug product, which is accomplished by monitoring the process parameters. The residual gas analyzer has emerged as a useful tool in determination of endpoint for primary and se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69d7cfcda75aa4e9f64b6e89ce64656c
https://pubmed.ncbi.nlm.nih.gov/36270539
https://pubmed.ncbi.nlm.nih.gov/36270539
Autor:
John F. Gamble, Ilgaz Akseli, Ana P. Ferreira, Michael Leane, Stephen Thomas, Mike Tobyn, Robert C. Wadams
Publikováno v:
International Journal of Pharmaceutics. 635:122743
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff3df71fc5afceeb5bd2c464ddbf9b85
https://doi.org/10.1016/j.ijpharm.2023.122743
https://doi.org/10.1016/j.ijpharm.2023.122743
Autor:
Amin Farshchi, Hervé Barjat, Stephen Checkley, Michael Leane, Mike Tobyn, Chris Morris, Furqan Tahir, Richard Anthony Storey, John F. Gamble, Toma Chitu, Neil Dawson, Andy Mitchell, Ana Patricia Ferreira, Kendal Pitt
Publikováno v:
Journal of Pharmaceutical Innovation. 16:181-196
Understanding and predicting the flow of bulk pharmaceutical materials could be key in enabling pharmaceutical manufacturing by continuous direct compression (CDC). This study examines whether, by taking powder and bulk measurements, and using statis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5934f75aee0af4cfdec854ab8551253b
https://doi.org/10.1007/s12247-020-09433-5
https://doi.org/10.1007/s12247-020-09433-5
Autor:
John F. Gamble, Mike Tobyn, Shawn Zhang, Aiden Zhu, Jakub Šalplachta, Jan Matula, Tomáš Zikmund, Jozef Kaiser, Peter Oberta
Publikováno v:
AAPS PharmSciTech. 23
Graphical Abstract.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfb17e020e614737ca1a742431cc4ea6
https://doi.org/10.1208/s12249-021-02184-7
https://doi.org/10.1208/s12249-021-02184-7
Autor:
Anuji Abraham, Andrea Pugliese, Lucy E. Hawarden, Dinu Iuga, Frédéric Blanc, Michael Toresco, Mike Tobyn, Daniel McNamara
Publikováno v:
Molecular Pharmaceutics
MOLECULAR PHARMACEUTICS
MOLECULAR PHARMACEUTICS
The bioavailability of insoluble crystalline active pharmaceutical ingredients (APIs) can be enhanced by formulation as amorphous solid dispersions (ASDs). One of the key factors of ASD stabilization is the formation of drug-polymer interactions at t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9c231d1e769e13f090e41b1adf10d98
https://pubmed.ncbi.nlm.nih.gov/34375100
https://pubmed.ncbi.nlm.nih.gov/34375100
Autor:
R. Greenwood, Conrad Davies, John W. Jones, Neil Dawson, James Clarke, Mike Tobyn, Andrew Ingram, John F. Gamble
Publikováno v:
AAPS PharmSciTech. 21(6)
The attrition of drug particles during the process of dry granulation, which may (or may not) be incorporated into granules, could be an important factor in determining the subsequent performance of that granulation, including key factors such as sti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b76a99ec59196bf8f34e15fa5f25fe9b
https://pubmed.ncbi.nlm.nih.gov/32743765
https://pubmed.ncbi.nlm.nih.gov/32743765
Autor:
Mike Tobyn, Angela Olsofsky, Sayantan Chattoraj, Wyatt J. Roth, Patrick David Daugherity, Todd McDermott
Publikováno v:
Journal of Pharmaceutical Sciences. 107:2267-2282
Sticking and picking during tablet manufacture has received increasing interest recently, as it causes tablet defects, downtime in manufacturing, and yield losses. The capricious nature of the problem means that it can appear at any stage of the deve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c4ccf2247a8891f156a0c24b4a20420
https://doi.org/10.1016/j.xphs.2018.04.029
https://doi.org/10.1016/j.xphs.2018.04.029
Autor:
Mike Tobyn, Faranak Nikfar, Admassu Abebe, Ana Patricia Ferreira, Omar Sprockel, Dolapo Olusanmi
Publikováno v:
International Journal of Pharmaceutics. 514:335-340
In the oral solid dosage form space, material physical properties have a strong impact on the behaviour of the formulation during processing. The ability to identify materials with similar characteristics (and thus expected to exhibit similar behavio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0984e0a3993cb96e960a23ba4c5bc10
https://doi.org/10.1016/j.ijpharm.2015.09.046
https://doi.org/10.1016/j.ijpharm.2015.09.046