Zobrazeno 1 - 1
of 1
pro vyhledávání: '"Mike T. Rudd"'
Autor:
Keith W. Rickert, Ming-Tain Lai, Daniel Riley, Melissa S. Egbertson, Mike T. Rudd, Kausik K. Nanda, Barbara Hanney, Shawn J. Stachel, Stephanie A. Kane, Jay A. Grobler, Ahren Iver Green, John M. Sanders, Christopher Daley, Paul Zuck, Vandna Munshi, Edward J. Brnardic, Kristen G. Jones, Darrell A. Henze, Alicja Krasowska-Zoladek, Hua-Poo Su, Mark T. Bilodeau, Yiwei Li, Dennis Murphy, Michael D. Leitl, Peter J. Manley
Publikováno v:
Journal of medicinal chemistry. 57(13)
We have identified several series of small molecule inhibitors of TrkA with unique binding modes. The starting leads were chosen to maximize the structural and binding mode diversity derived from a high throughput screen of our internal compound coll