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pro vyhledávání: '"Mike T. Migawa"'
Autor:
Balkrishen Bhat, Josh G. Nichols, Walt F. Lima, Stanley T. Crooke, Mike T. Migawa, Hongjiang Wu, Thazha P. Prakash, Tadensz K. Wyrzykiewicz
Publikováno v:
Journal of Biological Chemistry. 279:36317-36326
Human RNase H1 cleaves RNA exclusively in an RNA/DNA duplex; neither double-strand DNA nor double-strand RNA is a viable substrate. Previous studies suggest that the helical geometry and sugar conformation of the DNA and RNA may play a role in the se