Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Mike Schertzer"'
Autor:
Laetitia Kermasson, Jean-Pierre de Villartay, Patrick Revy, Mike Schertzer, Laurent Jullien, Arturo Londoño-Vallejo, Tangui Le Guen, Axelle Lefebvre
Publikováno v:
médecine/sciences. 29:1138-1144
RTEL1 (regulator of telomere length helicase 1) is a DNA helicase that has been identified more than 10 years ago. Many works since, mainly in the nematode Caenorhabditis elegans and the mouse, have highlighted its role in chromosomal stability, main
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62bcc25c83f0a753bb241b222fbb6484
https://doi.org/10.1051/medsci/20132912018
https://doi.org/10.1051/medsci/20132912018
Publikováno v:
Nucleic Acids Research. 32:3383-3391
Terminal restriction fragment analysis is the only method currently available for measuring telomere length in Caenorhabditis elegans. Its limitations include low sensitivity and interference by the presence of interstitial telomeric sequences in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37c696fa7c4d3ea59833a1d5bf891fb6
https://doi.org/10.1093/nar/gkh661
https://doi.org/10.1093/nar/gkh661
Autor:
Steven S.S. Poon, Elizabeth A. Chavez, Xiaoli Wu, Irma Vulto, Reza Pourvali, Makoto Kammori, Mike Schertzer, Andras Nagy, Marina Gertsenstein, Peter M. Lansdorp, Hao Ding, Patrick P.L. Tam, Sara Selig
Publikováno v:
Cell. 117(7):873-886
Little is known about the genes that regulate telomere length diversity between mammalian species. A candidate gene locus was previously mapped to a region on distal mouse Chr 2q. Within this region, we identified a gene similar to the dog-1 DNA heli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5afda181622dd0ef8dd4a2ec2f855b82
Autor:
Wasil A. Jastaniah, Hinh Ly, Jeffrey H. Davis, Tristram G. Parslow, Peter M. Lansdorp, Siu Li Yong, Elizabeth H. Blackburn, Mike Schertzer, Qin Ouyang
Publikováno v:
Blood. 106(4)
Heterozygous mutations of the human telomerase RNA template gene (TERC) have been described in patients with acquired aplastic anemia and the autosomal dominant form of dyskeratosis congenita (DKC). Patients with mutations in both TERC alleles have n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cc7e8b82ce8f407f5262162b4231b6e
https://pubmed.ncbi.nlm.nih.gov/15886322
https://pubmed.ncbi.nlm.nih.gov/15886322
Autor:
Scott Zuyderduyn, Steven J.M. Jones, Agnes Baross, Mike Schertzer, Peter M. Lansdorp, Marco A. Marra
Publikováno v:
Genes, chromosomescancer. 39(4)
Telomeres protect chromosomes from degradation, end-to-end fusion, and illegitimate recombination. Loss of telomeres may lead to cell death or senescence or may cause genomic instability, leading to tumor formation. Expression of human telomerase rev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9703db00abad34ee0e4000936376dd29
https://pubmed.ncbi.nlm.nih.gov/14978791
https://pubmed.ncbi.nlm.nih.gov/14978791
Autor:
Hao, Ding, Mike, Schertzer, Xiaoli, Wu, Marina, Gertsenstein, Sara, Selig, Makoto, Kammori, Reza, Pourvali, Steven, Poon, Irma, Vulto, Elizabeth, Chavez, Patrick P L, Tam, Andras, Nagy, Peter M, Lansdorp
Publikováno v:
Cell. 117(7)
Little is known about the genes that regulate telomere length diversity between mammalian species. A candidate gene locus was previously mapped to a region on distal mouse Chr 2q. Within this region, we identified a gene similar to the dog-1 DNA heli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a17ba1809892419b5165415676c50d24
https://pubmed.ncbi.nlm.nih.gov/15210109
https://pubmed.ncbi.nlm.nih.gov/15210109
Autor:
Rosalie M. Luiten, Alexander Röth, Hans Yssel, Peter M. Lansdorp, Jérôme Pène, H Spits, Elizabeth A. Chavez, Mike Schertzer
Publikováno v:
Blood, 102(3), 849-857. American Society of Hematology
The loss of telomeric DNA with each cell division contributes to the limited replicative lifespan of human T lymphocytes. Although telomerase is transiently expressed in T lymphocytes upon activation, it is insufficient to confer immortality. We have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2776f909b21385eead81798a9ad82851
https://pure.amc.nl/en/publications/telomerase-levels-control-the-lifespan-of-human-t-lymphocytes(b2330d6f-4934-4b3d-a13f-a0761de6c638).html
https://pure.amc.nl/en/publications/telomerase-levels-control-the-lifespan-of-human-t-lymphocytes(b2330d6f-4934-4b3d-a13f-a0761de6c638).html
Autor:
Stephen Wood, Mike Schertzer
Publikováno v:
Nucleic acids research. 19(23)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e5eb04fb1e9f68368d0a5db6391cce5
https://pubmed.ncbi.nlm.nih.gov/1754416
https://pubmed.ncbi.nlm.nih.gov/1754416
Publikováno v:
Genes, Chromosomes & Cancer; Apr2004, Vol. 39 Issue 4, p298-310, 13p