Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Mike Sabo"'
Autor:
Geoff Clarke, Howard Donninger, Raphael Jigo, Tariq Arshad, Becca von Baby, Rachel Ferrill, Mike Sabo, Joe Burlison, John Trent
Publikováno v:
Molecular Cancer Research. 21:B005-B005
Since RAS mutations are rare in Breast Cancer, RAS has not traditionally been considered as an important driver of this disease. However, RAS signaling pathways are frequently hyper-activated in breast cancers and genetic/epigenetic inactivation of R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2d698f449bc8ba111044dfa3c3e41cd
https://doi.org/10.1158/1557-3125.ras23-b005
https://doi.org/10.1158/1557-3125.ras23-b005
Autor:
Geoff Clarke, Tariq Arshad, Howard Donninger, Becca von Baby, Rachel Ferrill, Mike Sabo, Joe Burlison, John Trent
Publikováno v:
Molecular Cancer Research. 21:B006-B006
RAS oncogenes are frequently activated by mutations in pancreatic and lung cancer, where they appear to act as driving mutations. This study examines the activity of a series of novel direct RAS inhibitors with a predicted unique interaction region.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c6faa273b08f46ff19c8cf84821ad0fc
https://doi.org/10.1158/1557-3125.ras23-b006
https://doi.org/10.1158/1557-3125.ras23-b006