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Autor:
Hee-Sook Kim, John H.J. Petrini, Sangeetha Vijayakumar, James E. Haber, Jacob C. Harrison, Mike Reger, Clifford F. Weil
Publikováno v:
Genetics. 178:711-723
The Mre11 complex functions in double-strand break (DSB) repair, meiotic recombination, and DNA damage checkpoint pathways. Sae2 deficiency has opposing effects on the Mre11 complex. On one hand, it appears to impair Mre11 nuclease function in DNA re