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Data from KDM5B Is Essential for the Hyperactivation of PI3K/AKT Signaling in Prostate Tumorigenesis

Autor: Zhenbang Chen, Qin Yan, Robert J. Matusik, Samuel E. Adunyah, Xinchun Zhou, Billy R. Ballard, Tao Lu, Qi Liu, Michael G. Izban, Sherly I. Celada, Shang-Min Zhang, Mike R. Zou, Wenfu Lu, Thanigaivelan Kanagasabai, Guoliang Li

KDM5B (lysine[K]-specific demethylase 5B) is frequently upregulated in various human cancers including prostate cancer. KDM5B controls H3K4me3/2 levels and regulates gene transcription and cell differentiation, yet the contributions of KDM5B to prost

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f92281df5c765f7787c588440bdc38a7
https://doi.org/10.1158/0008-5472.c.6512665.v1

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Supplementary Figure from KDM5B Is Essential for the Hyperactivation of PI3K/AKT Signaling in Prostate Tumorigenesis

Suppl Figs S1-S8

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a230d28533f4eb86eedf0e632abebf6
https://doi.org/10.1158/0008-5472.22427422

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Supplementary Table from KDM5B Is Essential for the Hyperactivation of PI3K/AKT Signaling in Prostate Tumorigenesis

Table S1, S2 and S3

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23587c4cd28345225e4b483936192783
https://doi.org/10.1158/0008-5472.22427419.v1

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Capmatinib efficacy in patients with NSCLC identified as METex14 using an NGS-based liquid biopsy assay: Results from the GEOMETRY mono-1 study

Autor: Takashi Seto, Mike R. Zou, Edward B. Garon, Yiqun Yang, Harry J.M. Groen, Juergen Wolf, Egbert F. Smit, Andrea Chassot-Agostinho, Daniel Shao-Weng Tan, Ying Li, Rebecca S. Heist

Publikováno v: Journal of Clinical Oncology. 39:9111-9111

9111 Background: Capmatinib, a highly selective and potent MET inhibitor, was approved for patients (pts) with advanced MET exon 14 skipping mutation (METex14) NSCLC in the US and Japan, with the FoundationOne CDx (tissue NGS assay), based on results

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a4b49745f034a9b5a4eae7f56b198a03
https://doi.org/10.1200/jco.2021.39.15_suppl.9111

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Significance of glioma-associated oncogene homolog 1 (GLI1)expression in claudin-low breast cancer and crosstalk with the nuclear factor kappa-light-chain-enhancer of activated B cells (NFκB) pathway

Autor: Don X. Nguyen, Mike R. Zou, Sierra A. Colavito, David F. Stern, Qin Yan

Publikováno v: Breast Cancer Research : BCR

Introduction The recently identified claudin-low subtype of breast cancer is enriched for cells with stem-like and mesenchymal-like characteristics. This subtype is most often triple-negative (lacking the estrogen and progesterone receptors (ER, PR)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::774a6d010967aa8711241468ae00bcfa
https://doi.org/10.1186/s13058-014-0444-4

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