Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Mike Langhorne"'
Autor:
Lynn Barker, Mike Langhorne, Mehran Seid, Ribhi Shawar, J. J. Plattner, Burger Matthew, Jolene Kidney, Christy Hiebert, Manoj C. Desai, Daniel T. Chu
Publikováno v:
Bioorganic & Medicinal Chemistry. 14:5592-5604
A novel series of C(12) ethyl erythromycin derivatives have been discovered which exhibit in vitro and in vivo potency against key respiratory pathogens, including those resistant to erythromycin. The C(12) modification involves replacing the natural
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b0e8ba17b7902ccd0c1c3f87e80ab2b
https://doi.org/10.1016/j.bmc.2006.04.032
https://doi.org/10.1016/j.bmc.2006.04.032
Autor:
David R. Sherman, L Embuscado, T.E McKennon, Mike Langhorne, T Kline, E Naeemi, S. K. Tanaka, L. Goltry, S Cai, Lynn Barker, Ribhi Shawar, M Fromhold, A Bigelow, N Ihle, L. L. Brody, S.U Anderson, Mark J. Hickey, Lisa Nguyen, Paul Warrener, J Treiberg, P.R Witte, William R. Schwan
Publikováno v:
Bioorganic & Medicinal Chemistry. 8:73-93
As a strategy to increase the penetration of antibiotic drugs through the outer membrane of gram-negative pathogens, facilitated transport through siderophore receptors has been frequently exploited. Hydroxamic acids, catechols, or very close isoster
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eff5ff852cfb8a7d135084154be05eb4
https://doi.org/10.1016/s0968-0896(99)00261-8
https://doi.org/10.1016/s0968-0896(99)00261-8
Autor:
Daniel T. Chu, Mike Langhorne, Kelly Young, Christy Hiebert, Jolene Kidney, J. J. Plattner, Scott Anderson, Georgia Law Carroll, Kay Huh, Mehran Seid, Xiaodong Lin, Alice Rico, Manoj C. Desai, Lynn Barker, Ribhi Shawar, Burger Matthew
Publikováno v:
Journal of medicinal chemistry. 49(5)
A novel series of C12 vinyl erythromycin derivatives have been discovered which exhibit in vitro and in vivo potency against key respiratory pathogens. The C12 modification involves replacing the natural C12 methyl group in the erythromycin core with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e97c1aea270b45408d271b0571b25618
https://pubmed.ncbi.nlm.nih.gov/16509588
https://pubmed.ncbi.nlm.nih.gov/16509588