Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Mike Khan"'
Autor:
Mike Khan, Jerome S Harms, Yiping Liu, Jens Eickhoff, Jin Wen Tan, Tony Hu, Fengwei Cai, Erika Guimaraes, Sergio Costa Oliveira, Richard Dahl, Yong Cheng, Delia Gutman, Glen N Barber, Gary A Splitter, Judith A Smith
Publikováno v:
PLoS Pathogens, Vol 16, Iss 10, p e1009020 (2020)
Brucellosis, caused by a number of Brucella species, remains the most prevalent zoonotic disease worldwide. Brucella establish chronic infections within host macrophages despite triggering cytosolic innate immune sensors, including Stimulator of Inte
Externí odkaz:
https://doaj.org/article/d2b3bfb878264b17877fb7ed40ea6334
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Familial hypercholesterolemia (FH) is a common genetic cause of premature cardiovascular disease (CVD). The reported prevalence rates for both heterozygous FH (HeFH) and homozygous FH (HoFH) vary significantly, and this can be attributed, at least in
Externí odkaz:
https://doaj.org/article/c766dd24429a4b12bf780ada04a84fb7
Autor:
Yiping Liu, Zhan Ye, Xiang Li, Jennifer L. Anderson, Mike Khan, Douglas DaSilva, Marissa Baron, Deborah Wilson, Vera Bocoun, Lynn C. Ivacic, Steven J. Schrodi, Judith A. Smith
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
ObjectiveTumor necrosis factor alpha-induced protein 3 (TNFAIP3) is an anti-inflammatory protein implicated in multiple autoimmune and rheumatologic conditions. We hypothesized that lower levels of TNFAIP3 contributes to excessive cytokine production
Externí odkaz:
https://doaj.org/article/471b2a385afd4ab4b763466e0fa044b2
Autor:
Judith A Smith, Mike Khan, Diogo D Magnani, Jerome S Harms, Marina Durward, Girish K Radhakrishnan, Yi-Ping Liu, Gary A Splitter
Publikováno v:
PLoS Pathogens, Vol 9, Iss 12, p e1003785 (2013)
Brucella melitensis is a facultative intracellular bacterium that causes brucellosis, the most prevalent zoonosis worldwide. The Brucella intracellular replicative niche in macrophages and dendritic cells thwarts immune surveillance and complicates b
Externí odkaz:
https://doaj.org/article/e78fc4889d224b61b74840dbc5883805
Autor:
Judith A. Smith, Fengwei Cai, Mike Khan, Richard Dahl, Jens C. Eickhoff, Tony Hu, Yong Cheng, Jin Wen Tan, Jerome S. Harms, Sergio C. Oliveira, Glen N. Barber, Gary A. Splitter, Erika S. Guimarães, Yi-Ping Liu, Delia Gutman
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 16, Iss 10, p e1009020 (2020)
PLoS Pathogens, Vol 16, Iss 10, p e1009020 (2020)
Brucellosis, caused by a number of Brucella species, remains the most prevalent zoonotic disease worldwide. Brucella establish chronic infections within host macrophages despite triggering cytosolic innate immune sensors, including Stimulator of Inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b07cbba2440affbc11678c857329e2fc
http://europepmc.org/articles/PMC7647118
http://europepmc.org/articles/PMC7647118
Autor:
Jerome S. Harms, Jin Wen Tan, Gary A. Splitter, Tony Hu, Fengwei Cai, Jens C. Eickhoff, Delia Gutman, Richard Dahl, Erika S. Guimarães, Mike Khan, Yi-Ping Liu, Sergio C. Oliveira, Glen N. Barber, Judith A. Smith
Brucellosis, caused by Brucella bacteria species, remains the most prevalent zoonotic disease worldwide. Brucella establish chronic infections within host macrophages despite triggering cytosolic innate immune sensors, including Stimulator of Interfe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::081addc7d4c91d6cb5e6b99d895db56b
Autor:
Sergio C. Oliveira, Yi-Ping Liu, Fernanda Martins Marim, Cherisse Hall, Mike Khan, Menachem Banai, Jerome S. Harms, Leah Armon, Judith A. Smith, Gary A. Splitter
Publikováno v:
Infection and Immunity. 84:3458-3470
Brucella species are facultative intracellular bacteria that cause brucellosis, a chronic debilitating disease significantly impacting global health and prosperity. Much remains to be learned about how Brucella spp. succeed in sabotaging immune host
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c718c8b8952f8157f5f4cbabe40e3fe4
https://doi.org/10.1128/iai.00531-16
https://doi.org/10.1128/iai.00531-16
Autor:
Mike Khan, Tracey L Watson, Ian A Cree, Dimitris K. Grammatopoulos, Sarojini Pandey, Martin Crockard, Mark J Latten, Nigel P. Dyer, Kate L Lloyd, Anne Reiman
Publikováno v:
Annals of Clinical Biochemistry: International Journal of Laboratory Medicine. 53:654-662
Background Detection of disease-associated mutations in patients with familial hypercholesterolaemia is crucial for early interventions to reduce risk of cardiovascular disease. Screening for these mutations represents a methodological challenge sinc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7d8e50f9dfd70183ae0a6567be16ad2
https://doi.org/10.1177/0004563216629170
https://doi.org/10.1177/0004563216629170
Publikováno v:
The Journal of Applied Laboratory Medicine. 1:109-118
Background A key objective of the UK National Institute for Health and Care Excellence (NICE) pathway for diagnosis of familial hypercholesterolemia (FH) is the identification of affected relatives of index cases through cascade screening. At present
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0eae381dc3989272c9524c29cddc2e93
https://doi.org/10.1373/jalm.2016.020610
https://doi.org/10.1373/jalm.2016.020610
Autor:
Gary A. Splitter, Jerome S. Harms, Mike Khan, Cherisse Hall, Marina Durward-Diioia, Judith A. Smith
Publikováno v:
Infection and Immunity. 83:4759-4771
Brucella melitensis is a well-adapted zoonotic pathogen considered a scourge of mankind since recorded history. In some cases, initial infection leads to chronic and reactivating brucellosis, incurring significant morbidity and economic loss. The mec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::920b317af244b6d32522fac3c344e251
https://doi.org/10.1128/iai.01184-15
https://doi.org/10.1128/iai.01184-15