Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Mike Heimerikx"'
Autor:
Petra van der Stoop, Erwin A Boutsma, Danielle Hulsman, Sonja Noback, Mike Heimerikx, Ron M Kerkhoven, J Willem Voncken, Lodewyk F A Wessels, Maarten van Lohuizen
Publikováno v:
PLoS ONE, Vol 3, Iss 5, p e2235 (2008)
Polycomb repressive complex 1 (PRC1) core member Ring1b/Rnf2, with ubiquitin E3 ligase activity towards histone H2A at lysine 119, is essential for early embryogenesis. To obtain more insight into the role of Ring1b in early development, we studied i
Externí odkaz:
https://doaj.org/article/72cd3015ec06429d8a7c567a79714969
Autor:
Ron M Kerkhoven, Daoud Sie, Marja Nieuwland, Mike Heimerikx, Jorma De Ronde, Wim Brugman, Arno Velds
Publikováno v:
PLoS ONE, Vol 3, Iss 4, p e1980 (2008)
Eberwine(-like) amplification of mRNA adds distinct 6-10 bp nucleotide stretches to the 5' end of amplified RNA transcripts. Analysis of over six thousand microarrays reveals that probes containing motifs complementary to these stretches are associat
Externí odkaz:
https://doaj.org/article/c58d316ba760460dbc22fd6a6febd9ed
Autor:
Mike Heimerikx, Arno Velds, Ton N. Schumacher, Erwin Swart, Jeroen W. J. van Heijst, Carmen Gerlach, Ron M. Kerkhoven, Ramon Arens, Maria R. Castrucci, Koen Schepers, Daoud Sie
Publikováno v:
The Journal of Experimental Medicine
Journal of Experimental Medicine, 205(10), 2309-18. Rockefeller University Press
Schepers, K, Swart, E, van Heijst, J W J, Gerlach, C, Castrucci, M, Sie, D, Heimerikx, M, Velds, A, Kerkhoven, R M, Arens, R & Schumacher, T N M 2008, ' Dissecting T cell lineage relationships by cellular barcoding ', Journal of Experimental Medicine, vol. 205, no. 10, pp. 2309-18 . https://doi.org/10.1084/jem.20072462
Journal of Experimental Medicine, 205(10), 2309-18. Rockefeller University Press
Schepers, K, Swart, E, van Heijst, J W J, Gerlach, C, Castrucci, M, Sie, D, Heimerikx, M, Velds, A, Kerkhoven, R M, Arens, R & Schumacher, T N M 2008, ' Dissecting T cell lineage relationships by cellular barcoding ', Journal of Experimental Medicine, vol. 205, no. 10, pp. 2309-18 . https://doi.org/10.1084/jem.20072462
T cells, as well as other cell types, are composed of phenotypically and functionally distinct subsets. However, for many of these populations it is unclear whether they develop from common or separate progenitors. To address such issues, we develope
Autor:
Ron M. Kerkhoven, Jeroen Janssen, Jacob van den Born, Mike Heimerikx, Angelika M. Dräger, Floortje L. Kessler, Peter C. Huijgens, Johanna W.A.M. Celie, Sonja Zweegman
Publikováno v:
Matrix Biology, 26(7), 561-571. Elsevier
Zweegman, S, Kessler, F L, Kerkhoven, R M, Heimerikx, M, Celie, J W A M, Janssen, J J W M, Huijgens, P C, Drager, A M & van den Born, J 2007, ' Reduced supportive capacity of bone marrow stroma upon chemotherapy is mediated via changes in glycosaminoglycan profile ', Matrix Biology, vol. 26, no. 7, pp. 561-571 . https://doi.org/10.1016/j.matbio.2007.04.006
Matrix Biology, 26(7), 561-571
Zweegman, S, Kessler, F L, Kerkhoven, R M, Heimerikx, M, Celie, J W A M, Janssen, J J W M, Huijgens, P C, Drager, A M & van den Born, J 2007, ' Reduced supportive capacity of bone marrow stroma upon chemotherapy is mediated via changes in glycosaminoglycan profile ', Matrix Biology, vol. 26, no. 7, pp. 561-571 . https://doi.org/10.1016/j.matbio.2007.04.006
Matrix Biology, 26(7), 561-571
High dose chemotherapy and radiation have been found to impair the hematopoiesis-supportive capacity of bone marrow stroma. We now provide evidence for an important role of chemotherapy-induced alterations in stromal glycosaminoglycans (GAGs) in redu
Autor:
Armida W. M. Fabius, Eleonore Marielle Hijmans, Roderick L. Beijersbergen, René Bernards, Katrien Berns, Ron M. Kerkhoven, Jasper Mullenders, Arno Velds, Thijn R. Brummelkamp, Mike Heimerikx, Mandy Madiredjo
Publikováno v:
Cold Spring Harbor Symposia on Quantitative Biology. 69:439-446
Autor:
Mike Heimerikx, Danielle Hulsman, Lodewyk F. A. Wessels, Erwin Boutsma, Ron M. Kerkhoven, Petra van der Stoop, Maarten van Lohuizen, J. Willem Voncken, Sonja Noback
Publikováno v:
PLoS ONE
PLoS ONE, Vol 3, Iss 5, p e2235 (2008)
PLoS ONE, Vol 3, Iss 5, p e2235 (2008)
Background Polycomb repressive complex 1 (PRC1) core member Ring1b/Rnf2, with ubiquitin E3 ligase activity towards histone H2A at lysine 119, is essential for early embryogenesis. To obtain more insight into the role of Ring1b in early development, w
Autor:
Reuven Agami, Mike Heimerikx, Britta Weigelt, Arno Velds, Thijn R. Brummelkamp, René Bernards, Wei Ge, Wouter Nijkamp, Mandy Madiredjo, Guy Cavet, Katrien Berns, E. Marielle Hijmans, Peter S. Linsley, Jasper Mullenders, Roderick L. Beijersbergen, Ron M. Kerkhoven
Publikováno v:
Nature, 428(6981), 431. Nature Publishing Group
RNA interference (RNAi) is a powerful new tool with which to perform loss-of-function genetic screens in lower organisms and can greatly facilitate the identification of components of cellular signalling pathways. In mammalian cells, such screens hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c11a053590c6a93fcdb8908eae8f3a7
https://dspace.library.uu.nl/handle/1874/17768
https://dspace.library.uu.nl/handle/1874/17768
Autor:
Angelika M. Dräger, Jacob van den Born, Floortje L. Kessler, Mike Heimerikx, Sonja Zweegman, Ron M. Kerkhoven, Peter C. Huijgens
Publikováno v:
Blood. 104:1304-1304
High dose chemotherapy and radiation, as applied in stem cell transplantation procedures, have been found to impair the hematopoiesis-supportive capacity of bone marrow stroma. However, the molecular mechanisms involved are far from elucidated yet. A