Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Mike H. Cardone"'
Publikováno v:
Proceedings of the National Academy of Sciences. 100:9330-9335
Signal transduction in mammalian cells is mediated by complex networks of interacting proteins. Understanding these networks at a circuit level requires devices to measure the amounts and activities of multiple proteins in a rapid and accurate manner
Autor:
Sebastian Wesselborg, Peter Brossart, Alberto Ballestrero, Eleonora Barbieri, Franco Patrone, Claus Belka, Anna Garuti, Mike H. Cardone, Alessio Nencioni, Ilaria Rocco, Christopher P. Dillon, Fei Hua, Rayka Yokoo, Christoph Scheiermann
Publikováno v:
Blood, Vol. 105, No 8 (2005) pp. 3255-62
Proteasome inhibitors exhibit antitumor activity against malignancies of different histology. Yet, the mechanisms underlying this effect are poorly understood. Recent evidence indicates that antiapoptotic factors may also accumulate as a consequence