Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Mike Fried"'
Autor:
Hannah Mamuszka, Blake Long, Tobin Dickerson, Margaret Snyder, Paul Montgomery, Mike Fried, Martyn Gross, Jashin Wu, Lena Chaihorsky
Publikováno v:
SKIN The Journal of Cutaneous Medicine. 5:372-387
Objective: This study was a budget impact analysis based on a budget impact model (BIM) and formularies from different commercial payer types (excluding Medicare and Medicaid). The primary objective of this study was to determine the potential cost s
Autor:
David Ascheid, Magdalena Baumann, Jürgen Pinnecker, Mike Friedrich, Daniel Szi-Marton, Cornelia Medved, Maja Bundalo, Vanessa Ortmann, Asli Öztürk, Rajender Nandigama, Katherina Hemmen, Süleymann Ergün, Alma Zernecke, Matthias Hirth, Katrin G. Heinze, Erik Henke
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-23 (2024)
Abstract Targeting the supportive tumor microenvironment (TME) is an approach of high interest in cancer drug development. However, assessing TME-targeted drug candidates presents a unique set of challenges. We develop a comprehensive screening platf
Externí odkaz:
https://doaj.org/article/b19449241bfb4bd295570f630d2e8595
Autor:
Till Karwen, Katarzyna Kolczynska‐Matysiak, Carina Gross, Mona C Löffler, Mike Friedrich, Angel Loza‐Valdes, Werner Schmitz, Magdalena Wit, Filip Dziaczkowski, Andrei Belykh, Jonathan Trujillo‐Viera, Rabih El‐Merahbi, Carsten Deppermann, Sameena Nawaz, Benoit Hastoy, Agnieszka Demczuk, Manuela Erk, Mariusz R Wieckowski, Patrik Rorsman, Katrin G Heinze, David Stegner, Bernhard Nieswandt, Grzegorz Sumara
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 9, Pp 1-23 (2023)
Abstract Hyperreactive platelets are commonly observed in diabetic patients indicating a potential link between glucose homeostasis and platelet reactivity. This raises the possibility that platelets may play a role in the regulation of metabolism. P
Externí odkaz:
https://doaj.org/article/974cd37e10194d4682e8df439ae20f8d
Autor:
David Ascheid, Magdalena Baumann, Caroline Funke, Julia Volz, Jürgen Pinnecker, Mike Friedrich, Marie Höhn, Rajender Nandigama, Süleyman Ergün, Bernhard Nieswandt, Katrin G. Heinze, Erik Henke
Publikováno v:
Biology Direct, Vol 18, Iss 1, Pp 1-15 (2023)
Abstract In tumor therapy anti-angiogenic approaches have the potential to increase the efficacy of a wide variety of subsequently or co-administered agents, possibly by improving or normalizing the defective tumor vasculature. Successful implementat
Externí odkaz:
https://doaj.org/article/b1a63164057a41fda92985124212471c
Autor:
Ruiqi Liu, Mike Friedrich, Katherina Hemmen, Kerstin Jansen, Mateus C. Adolfi, Manfred Schartl, Katrin G. Heinze
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
Xiphophorus fish exhibit a clear phenotypic polymorphism in puberty onset and reproductive strategies of males. In X. nigrensis and X. multilineatus, puberty onset is genetically determined and linked to a melanocortin 4 receptor (Mc4r) polymorphism
Externí odkaz:
https://doaj.org/article/e3dfc4caf3044b7580b86346898723c5
Autor:
Khanh N. C. Duong, Lan M. Le, Sajesh K. Veettil, Pantakarn Saidoung, Warintorn Wannaadisai, Richard E. Nelson, Mike Friedrichs, Barbara E. Jones, Andrew T. Pavia, Makoto M. Jones, Matthew H. Samore, Nathorn Chaiyakunapruk
Publikováno v:
Frontiers in Public Health, Vol 11 (2023)
BackgroundMeta-analyses have investigated associations between race and ethnicity and COVID-19 outcomes. However, there is uncertainty about these associations’ existence, magnitude, and level of evidence. We, therefore, aimed to synthesize, quanti
Externí odkaz:
https://doaj.org/article/e549751a041b4fdca0aa4070aa1962e8
Autor:
Berger, Gabriel ††The author expresses his thanks and acknowledges his debts to Takayuki Oda for introducing the topics considered in this paper and to Mike Fried for valuable discussions regarding Hurwitz spaces and connections with the modular group. We note that similar topics have been considered earlier by Helmut Voelklein, whose primary interest was the realization of certain finite groups of Lie type as Galois groups over ℚ.
Publikováno v:
In Journal of Algebra 1 April 1999 214(1):276-300
Autor:
Natalia Sergina, Ching Hang Wong, Deepika Ahuja, Mark M. Moasser, Dean Sheppard, Danislav S. Spassov, Mike Fried
Publikováno v:
Molecular and Cellular Biology. 31:766-782
Trask is a recently described transmembrane substrate of Src kinases whose expression and phosphorylation has been correlated with the biology of some cancers. Little is known about the molecular functions of Trask, although its phosphorylation has b
Autor:
Mike Fried, Ayse Metin, Alison McDowall, Siegfried Ussar, Ian Tomlinson, Rachel Evans, Nancy Hogg, Lena Svensson, Markus Moser, Irene Patzak, Kimberley Howarth
Publikováno v:
Nature Medicine. 15:306-312
Integrins are the major adhesion receptors of leukocytes and platelets. Beta1 and beta2 integrin function on leukocytes is crucial for a successful immune response and the platelet integrin alpha(IIb)beta3 initiates the process of blood clotting thro