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Autor:
Janak R. Wedagedera, Anthonia Afuape, Siri Kalyan Chirumamilla, Hiroshi Momiji, Robert Leary, Mike Dunlavey, Richard Matthews, Khaled Abduljalil, Masoud Jamei, Frederic Y. Bois
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 11, Iss 6, Pp 755-765 (2022)
Abstract Physiologically‐based pharmacokinetic (PBPK) models usually include a large number of parameters whose values are obtained using in vitro to in vivo extrapolation. However, such extrapolations can be uncertain and may benefit from inclusio
Externí odkaz:
https://doaj.org/article/b22a6cafc47a40658b0d29adf692a9fc