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Autor:
John C. Reed, Christina L. Kress, Do-Sung Kim, Ki-Chan Ha, Geum-Hwa Lee, Mike Cuddy, Hyung-Ryong Kim, Soo-Wan Chae, Han-Jung Chae, Hyun-Kyung Kim
Publikováno v:
Journal of Biological Chemistry. 282:21618-21628
The Bax inhibitor-1 (BI-1) is an anti-apoptotic protein that is located in endoplasmic reticulum (ER) membranes and protects cells from ER stress-induced apoptosis. The ER is associated with generation of reactive oxygen species (ROS) through oxidati