Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Mike C Wolf"'
Autor:
Frederic Vigant, Jihye Lee, Axel Hollmann, Lukas B Tanner, Zeynep Akyol Ataman, Tatyana Yun, Guanghou Shui, Hector C Aguilar, Dong Zhang, David Meriwether, Gleyder Roman-Sosa, Lindsey R Robinson, Terry L Juelich, Hubert Buczkowski, Sunwen Chou, Miguel A R B Castanho, Mike C Wolf, Jennifer K Smith, Ashley Banyard, Margaret Kielian, Srinivasa Reddy, Markus R Wenk, Matthias Selke, Nuno C Santos, Alexander N Freiberg, Michael E Jung, Benhur Lee
Publikováno v:
PLoS Pathogens, Vol 9, Iss 4, p e1003297 (2013)
LJ001 is a lipophilic thiazolidine derivative that inhibits the entry of numerous enveloped viruses at non-cytotoxic concentrations (IC50 ≤ 0.5 µM), and was posited to exploit the physiological difference between static viral membranes and biogeni
Externí odkaz:
https://doaj.org/article/5782a66da0c04ff5a689050288b55985
Autor:
Yao E Wang, Arnold Park, Michael Lake, Mickey Pentecost, Betsabe Torres, Tatyana E Yun, Mike C Wolf, Michael R Holbrook, Alexander N Freiberg, Benhur Lee
Publikováno v:
PLoS Pathogens, Vol 6, Iss 11, p e1001186 (2010)
Paramyxoviruses are known to replicate in the cytoplasm and bud from the plasma membrane. Matrix is the major structural protein in paramyxoviruses that mediates viral assembly and budding. Curiously, the matrix proteins of a few paramyxoviruses have
Externí odkaz:
https://doaj.org/article/6b21b19e495a41a9bde4c6acd5afe674
Autor:
Oscar A Negrete, Mike C Wolf, Hector C Aguilar, Sven Enterlein, Wei Wang, Elke Mühlberger, Stephen V Su, Andrea Bertolotti-Ciarlet, Ramon Flick, Benhur Lee
Publikováno v:
PLoS Pathogens, Vol 2, Iss 2, p e7 (2006)
EphrinB2 was recently discovered as a functional receptor for Nipah virus (NiV), a lethal emerging paramyxovirus. Ephrins constitute a class of homologous ligands for the Eph class of receptor tyrosine kinases and exhibit overlapping expression patte
Externí odkaz:
https://doaj.org/article/1979505c212f47d0a857785230a1e047
Autor:
Mike C. Wolf, Alexander N. Freiberg, Tinghu Zhang, Zeynep Akyol-Ataman, Andrew Grock, Patrick W. Hong, Jianrong Li, Natalya F. Watson, Angela Q. Fang, Hector C. Aguilar, Matteo Porotto, Anna N. Honko, Robert Damoiseaux, John P. Miller, Sara E. Woodson, Steven Chantasirivisal, Vanessa Fontanes, Oscar A. Negrete, Paul Krogstad, Asim Dasgupta, Anne Moscona, Lisa E. Hensley, Sean P. Whelan, Kym F. Faull, Michael R. Holbrook, Michael E. Jung, Benhur Lee
Publikováno v:
Proceedings of the National Academy of Sciences. 107:3157-3162
We describe an antiviral small molecule, LJ001, effective against numerous enveloped viruses including Influenza A, filoviruses, poxviruses, arenaviruses, bunyaviruses, paramyxoviruses, flaviviruses, and HIV-1. In sharp contrast, the compound had no
Publikováno v:
Virology Journal. 2009, Vol. 6, p119-129. 11p.