Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Mike Althaus"'
Autor:
Rene Y. Lawong, Fabian May, Etang C. Etang, Philipp Vorrat, Jonas George, Julia Weder, Dagmar Kockler, Matthias Preller, Mike Althaus
Publikováno v:
Membranes, Vol 13, Iss 5, p 529 (2023)
The epithelial sodium channel (ENaC) is a key regulator of sodium homeostasis that contributes to blood pressure control. ENaC open probability is adjusted by extracellular sodium ions, a mechanism referred to as sodium self-inhibition (SSI). With a
Externí odkaz:
https://doaj.org/article/998b94fae88a4d7789ded2ecfdddf666
Publikováno v:
Biomolecules, Vol 12, Iss 10, p 1404 (2022)
SLC6A14 (ATB0,+) is unique among SLC proteins in its ability to transport 18 of the 20 proteinogenic (dipolar and cationic) amino acids and naturally occurring and synthetic analogues (including anti-viral prodrugs and nitric oxide synthase (NOS) inh
Externí odkaz:
https://doaj.org/article/e25bf220a65546b59212d9766070a338
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Hydrogen sulfide (H2S) has been recognized as a signalling molecule which affects the activity of ion channels and transporters in epithelial cells. The cystic fibrosis transmembrane conductance regulator (CFTR) is an epithelial anion channe
Externí odkaz:
https://doaj.org/article/1e2fb55eee574e67ad36863dafaef571
Autor:
Chrissy Kandel, Patricia Schmidt, Alexander Perniss, Maryam Keshavarz, Paul Scholz, Sabrina Osterloh, Mike Althaus, Wolfgang Kummer, Klaus Deckmann
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 6 (2018)
Cholinergic polymodal chemosensory cells in the mammalian urethra (urethral brush cells = UBC) functionally express the canonical bitter and umami taste transduction signaling cascade. Here, we aimed to determine whether UBC are functionally equipped
Externí odkaz:
https://doaj.org/article/1cd1411079e24ffc964889ba81f265c3
Autor:
Anna Zakrzewicz, Katrin Richter, Alisa Agné, Sigrid Wilker, Kathrin Siebers, Bijan Fink, Gabriela Krasteva-Christ, Mike Althaus, Winfried Padberg, Arik J. Hone, J. Michael McIntosh, Veronika Grau
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 11 (2017)
Recently, we discovered a cholinergic mechanism that inhibits the adenosine triphosphate (ATP)-dependent release of interleukin-1β (IL-1β) by human monocytes via nicotinic acetylcholine receptors (nAChRs) composed of α7, α9 and/or α10 subunits.
Externí odkaz:
https://doaj.org/article/8e2a590967604fde86262405c8b26c54
Autor:
Maryam Keshavarz, Heike Schwarz, Petra Hartmann, Silke Wiegand, Melanie Skill, Mike Althaus, Wolfgang Kummer, Gabriela Krasteva-Christ
Publikováno v:
Frontiers in Physiology, Vol 8 (2017)
An increased bronchoconstrictor response is a hallmark in the progression of obstructive airway diseases. Acetylcholine and 5-hydroxytryptamine (5-HT, serotonin) are the major bronchoconstrictors. There is evidence that both cholinergic and serotoner
Externí odkaz:
https://doaj.org/article/8b56361c8a5f4cef8a4a9d9589f948db
Autor:
Alexandra Erb, Mike Althaus
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e100971 (2014)
Hydrogen sulfide (H2S) is well known as a highly toxic environmental chemical threat. Prolonged exposure to H2S can lead to the formation of pulmonary edema. However, the mechanisms of how H2S facilitates edema formation are poorly understood. Since
Externí odkaz:
https://doaj.org/article/c140d205e3dc4a878630fa862e31664c
Publikováno v:
Pulmonary Medicine, Vol 2011 (2011)
The development of pulmonary edema can be considered as a combination of alveolar flooding via increased fluid filtration, impaired alveolar-capillary barrier integrity, and disturbed resolution due to decreased alveolar fluid clearance. An important
Externí odkaz:
https://doaj.org/article/cb5caf18679b449fa4ec58a15520d15e
Publikováno v:
The Journal of Physiology
J Physiol 601.9 (2023) pp 1611–1623
J Physiol 601.9 (2023) pp 1611–1623
Synthesis of DNA fragments based on gene sequences available in public resources has become an efficient and affordable method that gradually replaced traditional cloning efforts such as PCR cloning from cDNA. However, database entries based on genom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a41fbbe4157a1a451699a6de31b20cc
https://pub.h-brs.de/frontdoor/index/index/docId/6714
https://pub.h-brs.de/frontdoor/index/index/docId/6714
Autor:
JinHeng Lin, Sean M. Gettings, Khaoula Talbi, Rainer Schreiber, Michael J. Taggart, Matthias Preller, Karl Kunzelmann, Mike Althaus, Michael A. Gray
Publikováno v:
Pflügers Archiv: European Journal of Physiology
Pflugers Arch-Eur J Physiol 475, 167–179 (2023)
Pflugers Arch-Eur J Physiol 475, 167–179 (2023)
The cystic fibrosis transmembrane conductance regulator (CFTR) anion channel and the epithelial Na+ channel (ENaC) play essential roles in transepithelial ion and fluid transport in numerous epithelial tissues. Inhibitors of both channels have been i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dce82df3ee85d7e50006e23e06b319ed
https://pub.h-brs.de/files/6457/s00424-022-02758-9.pdf
https://pub.h-brs.de/files/6457/s00424-022-02758-9.pdf