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pro vyhledávání: '"Mike Acker"'
Autor:
Mike Acker
Build your communication confidence and master the ability to inspire your audience In Speak with Confidence: Overcome Self-Doubt, Communicate Clearly, and Inspire Your Audience, keynote speaker, author, and executive communication coach Mike Acker d
Autor:
Movarid Mohseni, Alison R. Erickson, Jonathan R. LaRochelle, Steven P. Gygi, Lily A. Chylek, Mike Acker, Matthew J. LaMarche, Vemulapalli, Peter K. Sorger, Stephen C. Blacklow, Kartik Subramanian
SHP2 is a protein tyrosine phosphatase that normally potentiates intracellular signaling by growth factors, antigen receptors, and some cytokines; it is frequently mutated in childhood leukemias and other cancers. Here, we examine the role of SHP2 in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5bf769f194e2446ebdcee979c9ecde5
Autor:
Chen Liu, Patrick James Sarver, Troy Smith, Huaixiang Hao, Ho Man Chan, Ying-Nan Chen, Robert Koenig, Brant Firestone, Murphy Hentemann, Martin Sendzik, Mitsunori Kato, Hongyun Wang, Eric McNeill, Ping Wang, Jorge Garcia-Fortanet, Jeff Bagdanoff, Zhouliang Chen, Gang Liu, Movarid Mohseni, Michelle Fodor, Mike Acker, Travis Stams, Bing Yu, Chris Towler, Shumei Liu, Michael Dore, Stan Spence, Laura R. La Bonte, Sarah Williams, Matthew J. LaMarche, Rukundo Ntaganda
Publikováno v:
Cancer Research. 79:LB-005
Protein tyrosine phosphatase SHP2 is an oncoprotein associated with cancer as well as a potential immune modulator due to its role in the programmed cell death PD-L1/PD-1 pathway. Small molecule inhibition of SHP2 has been widely investigated includi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::338a19a58057115831aed52cd1285a8a
https://doi.org/10.1158/1538-7445.am2019-lb-005
https://doi.org/10.1158/1538-7445.am2019-lb-005
Autor:
Raymond Pagliarini, Huili Zhai, Julian Levell, David Jiang, Mike Acker, Fallon Lin, John S. Gounarides, Veronica Saenz-Vash, Joy Fletcher
Publikováno v:
Cancer Research. 73:A20-A20
Highly recurrent somatic mutations in the isocitrate dehydrogenase (IDH) 1 and 2 enzymes have been identified in a variety of tumor types including GBM and glioma subtypes, acute myelogenous leukemia, chondrosarcoma, and cholangiocarcinoma, among oth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41d89f73ea37099990435060121a91fd
https://doi.org/10.1158/1538-7445.cec13-a20
https://doi.org/10.1158/1538-7445.cec13-a20