Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Mike, Shires"'
Autor:
Christopher Williams, Faye Elliott, Mike Shires, Henry Wood, Liping Zhang, Zuo Zhao, Isaac Bai, Dongyao Yan, Faranak Aghaei, Uday Kurkure, Chris Bacon, Sarah E Coupland, Simon Cross, D Chas Mangham, Abhik Mukherjee, Jenny F. Seligmann, Nicholas West, Shalini Singh, Kandavel Shanmugam, Philip Quirke
Publikováno v:
Journal of Clinical Oncology. 41:203-203
203 Background: AREG and EREG are ligands of EGFR. AI assisted IHC evaluation of tumor AREG/EREG expression predicted benefit from anti-EGFR therapy in a retrospective analysis of the PICCOLO trial of second-line irinotecan ± panitumumab. Here, we s
Autor:
Christopher Williams, Richard G Gray, Mike Shires, Liping Zhang, Zuo Zhao, Isaac Bai, Dongyao Yan, Sarah Dance, Faranak Aghaei, Gemma Hemmings, Michael Hale, Uday Kurkure, Christoph Guetter, Susan D Richman, Gordon Hutchins, Jenny F. Seligmann, Nicholas West, Shalini Singh, Kandavel Shanmugam, Philip Quirke
Publikováno v:
Journal of Clinical Oncology. 41:204-204
204 Background: High CD3+ (all) and CD8+ (cytotoxic) T cell densities in the core (CT) and invasive margin (IM) of primary CRCs have been shown to be associated with superior prognosis at all stages of disease. Their predictive effect on benefit from
Autor:
Robert R. Thomson, Jonathan D. Shephard, Rainer J. Beck, David Jayne, Nicholas P. West, Mike Shires, Duncan Paul Hand, Ioannis Bitharas, T Maisey, Andrew J. Moore
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports
Scientific Reports
Endoluminal surgery for the treatment of colorectal neoplasia is typically carried out using electrocautery tools which imply limited precision and the risk of harm through collateral thermal damage to the adjacent healthy tissue. As a potential alte
Publikováno v:
Analytical Cellular Pathology, Vol 2014 (2014)
Externí odkaz:
https://doaj.org/article/39d2c5572f6c4a9cb92efe84cae97510
Publikováno v:
Analytical Cellular Pathology, Vol 2014 (2014)
Externí odkaz:
https://doaj.org/article/0e8d096fbf7542d78e39c82e9d65f7fc
Autor:
Clare, Gilham, Christine, Rake, John, Hodgson, Andrew, Darnton, Garry, Burdett, James, Peto Wild, Michelle, Newton, Andrew G, Nicholson, Leslie, Davidson, Mike, Shires, Tom, Treasure, Julian, Peto, Anthony, De Soyza
Publikováno v:
International Journal of Epidemiology
Background Occupational and environmental airborne asbestos concentrations are too low and variable for lifetime exposures to be estimated reliably, and building workers and occupants may suffer higher exposure when asbestos in older buildings is dis
Autor:
Aongus McCarthy, Rainer J. Beck, Donald R. Risbridger, Syam Mohan P. C. Mohanan, David Jayne, Mike Shires, Jonathan D. Shephard
Publikováno v:
Novel Biophotonics Techniques and Applications V.
Colorectal cancer is the fourth-most prominent cause of cancer related fatalities across the globe. Conventional electrocautery techniques used in the resection of colon tissue cause a relatively high degree of collateral damage to the healthy tissue
Autor:
Philip Quirke, Matthew T. Seymour, Susan D. Richman, Faye Elliott, Jenny F. Seligmann, Dongyao Yan, Isaac Bai, Mike Shires, Nicholas P. West, Andrea Muranyi, Jenny Barrett, Liping Zhang, Christopher Williams, Kandavel Shanmugam, Christoph Guetter, Shalini Singh
Publikováno v:
Journal of Clinical Oncology. 39:111-111
111 Background: High tumor mRNA levels of the EGFR ligands, AREG and EREG are associated with anti-EGFR agent response in patients (pts) with RAS-wt mCRC, regardless of tumor location. However, ligand RNA assays have not been adopted into routine cli
Autor:
David Jayne, Sarah L. Perry, Mike Shires, Jonathan D. Shephard, Duncan Paul Hand, Syam Mohan P. C. Mohanan, Wojciech Stanisław Góra, Rainer J. Beck
Publikováno v:
SPIE Proceedings.
Local resection of early stage tumors in the large bowel via colonoscopy has been a widely accepted surgical modality for colon neoplasm treatment. The conventional electrocautery techniques used for the resection of neoplasia in the mucosal or submu
Autor:
Eamonn Sheridan, Chris F. Inglehearn, Murugan Saktivel, Phillis Lakeman, Rohit Shetty, Anandula Venkataramana, Manir Ali, Sabrina Carrella, Bishwanath Pal, Ian M. Carr, Alex W. Hewitt, James A. Poulter, Maria M. van Genderen, Musallam Al-Araimi, Govindasamy Kumaramanickavel, Vedam L. Ramprasad, Mike Shires, David A. Mackey, David A. Parry, Carmel Toomes, Kamron N. Khan, Andrew R. Webster, Panagiotis I. Sergouniotis, Anthony T. Moore, Sandro Banfi, Moin Mohamed, Alex Tai Loong Tan, Ivan Conte, John Bradbury
Publikováno v:
American journal of human genetics, 93(6), 1143-1150. Cell Press
Poulter, J A, Al-Araimi, M, Conte, I, van Genderen, M M, Sheridan, E, Carr, I M, Parry, D A, Shires, M, Carrella, S, Bradbury, J, Khan, K, Lakeman, P, Sergouniotis, P I, Webster, A R, Moore, A T, Pal, B, Mohamed, M D, Venkataramana, A, Ramprasad, V, Shetty, R, Saktivel, M, Kumaramanickavel, G, Tan, A, Mackey, D A, Hewitt, A W, Banfi, S, Ali, M, Inglehearn, C F & Toomes, C 2013, ' Recessive Mutations in SLC38A8 Cause Foveal Hypoplasia and Optic Nerve Misrouting without Albinism ', American journal of human genetics, vol. 93, no. 6, pp. 1143-1150 . https://doi.org/10.1016/j.ajhg.2013.11.002
American journal of human genetics, vol 93, iss 6
Poulter, J A, Al-Araimi, M, Conte, I, van Genderen, M M, Sheridan, E, Carr, I M, Parry, D A, Shires, M, Carrella, S, Bradbury, J, Khan, K, Lakeman, P, Sergouniotis, P I, Webster, A R, Moore, A T, Pal, B, Mohamed, M D, Venkataramana, A, Ramprasad, V, Shetty, R, Saktivel, M, Kumaramanickavel, G, Tan, A, Mackey, D A, Hewitt, A W, Banfi, S, Ali, M, Inglehearn, C F & Toomes, C 2013, ' Recessive Mutations in SLC38A8 Cause Foveal Hypoplasia and Optic Nerve Misrouting without Albinism ', American journal of human genetics, vol. 93, no. 6, pp. 1143-1150 . https://doi.org/10.1016/j.ajhg.2013.11.002
American journal of human genetics, vol 93, iss 6
Foveal hypoplasia and optic nerve misrouting are developmental defects of the visual pathway and only co-occur in connection with albinism; to date, they have only been associated with defects in the melanin-biosynthesis pathway. Here, we report that