Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Mike, Kunis"'
Autor:
H Steve, Zhang, Dingang, Liu, Yan, Huang, Stefan, Schmidt, Reed, Hickey, Dmitry, Guschin, Haili, Su, Ion S, Jovin, Mike, Kunis, Sarah, Hinkley, Yuxin, Liang, Linda, Hinh, S Kaye, Spratt, Casey C, Case, Edward J, Rebar, Barbara E, Ehrlich, Barbara, Ehrlich, Philip D, Gregory, Frank J, Giordano
Publikováno v:
Molecular Therapy
Selective inhibition of disease-related proteins underpins the majority of successful drug–target interactions. However, development of effective antagonists is often hampered by targets that are not druggable using conventional approaches. Here, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcf6d75f77ecc7bd1ea7a45b7b9474c4
http://europepmc.org/articles/PMC3412484
http://europepmc.org/articles/PMC3412484
Autor:
Richard T. Surosky, Katsutoshi Yokoi, Dmitry Guschin, Philip D. Gregory, Shu Kachi, Liza M Africa, Huanda Steve Zhang, Qi Yu, Sharon Kaye Spratt, Robin R. Ali, James W B Bainbridge, Kamaljit S. Balaggan, Peter A. Campochiaro, Mike Kunis
Publikováno v:
Molecular therapy : the journal of the American Society of Gene Therapy. 15(11)
Zinc finger protein transcription factors (ZFP TFs) have been shown to positively or negatively regulate the expression of endogenous genes involved in a number of different disease processes. In this study we investigated whether gene transfer of an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb32a83c6a0372d23dc6c50f4f13618c
https://pubmed.ncbi.nlm.nih.gov/17700545
https://pubmed.ncbi.nlm.nih.gov/17700545
Autor:
Edward J. Rebar, Reed Hickey, Dale Ando, J. Tyler Martin, Simon Chandler, Yuxin Liang, Dinggang Liu, Frank J. Giordano, Xiaohong Zhong, Lei Zhang, Philip D. Gregory, Yan Huang, H. Steve Zhang, Casey C. Case, Dmitry Guschin, S. Kaye Spratt, Linda Hinh, Mike Kunis, Danny F Xia
Publikováno v:
Molecular Therapy. 11:S18
Improper calcium handling of the heart is a hallmark of patients with congestive heart failure (CHF). Because calcium is critical for cardiac contractility, proteins that regulate calcium homeostasis are potential targets treating CHF. Phospholamban
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93f6a921a6cb618a9d86b52c9d656cd3
https://doi.org/10.1016/j.ymthe.2005.06.071
https://doi.org/10.1016/j.ymthe.2005.06.071
Autor:
Mike Kunis, Reed Hickey, Edward J. Rebar, S. Kaye Spratt, J. Tyler Martin, Casey C. Case, Deng-Feng Xia, Simon Chandler, Xiaohong Zhong, Frank J. Giordano, H. Steven Zhang, Lei Zhang, Philip D. Gregory, Yuxin Liang, Linda Hinh, Dmitry Guschin
Publikováno v:
Molecular Therapy. 9:S356
Phospholamban (PLN) is a critical regulator of cardiac calcium homeostasis and muscle contractility. Recent studies have demonstrated that ablation or inhibition of PLN function can improve cardiac contractile properties in animal models of congestiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2de6e5c4655aa7e89aa84b830c0ace89
https://doi.org/10.1016/j.ymthe.2004.06.857
https://doi.org/10.1016/j.ymthe.2004.06.857