Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Mikayo Hayashi"'
Autor:
Miyajima Rin, Yu Yamashita, Nishikawa Yuki, Kazumi Kondo, Sakata Yasuyo, Masaki Tanaka, Otani Yuki, Hayashi Takashi, Takashi Wadatsu, Koji Sakai, Mikayo Hayashi
Publikováno v:
ACS chemical biology. 15(9)
Significant advancement of chemoproteomics has contributed to uncovering the mechanism of action (MoA) of small-molecule drugs by characterizing drug-protein interactions in living systems. However, cell-membrane proteins such as G protein-coupled re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bbc9375c5e0cc5024dfde702b7f1bdc
https://pubmed.ncbi.nlm.nih.gov/32786265
https://pubmed.ncbi.nlm.nih.gov/32786265
Autor:
Akihito Nishiyama, Makoto Matsumoto, Tohru Abe, Sohkichi Matsumoto, Kimiko Itoh, Yoshitaka Tateishi, Shaban A. Kaboso, Tsutomu Sato, Ryuki Kitamoto, Xiuhao Chen, Kentaro Kaneko, Yusuke Inoue, Mikayo Hayashi, Mayuko Osada-Oka, Yoshikazu Kawano, Mamoru Fujiwara, Yukiko Nishiuchi, Masanori Kawasaki
Publikováno v:
Antimicrob Agents Chemother
Delamanid (DLM), a nitro-dihydroimidazooxazole derivative currently approved for pulmonary multidrug-resistant tuberculosis (TB) therapy, is a prodrug activated by mycobacterial 7,8-didemethyl-8-hydroxy 5-deazaflavin electron transfer coenzyme (F(420
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e37364cfd6ccad045c35200f11fab65
https://pubmed.ncbi.nlm.nih.gov/32152081
https://pubmed.ncbi.nlm.nih.gov/32152081
Publikováno v:
European Journal of Organic Chemistry. 2016:4800-4804
Enantioenriched, polycyclic compounds were obtained from a simple acylphloroglucinol scaffold. Highly enantioselective dearomatization was accomplished using a Trost ligand- palladium(0) complex. A computational DFT model was developed to rationalize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff3d91bf45fb1fa0bff383f77fd4d6b4
https://doi.org/10.1002/ejoc.201601003
https://doi.org/10.1002/ejoc.201601003
Publikováno v:
European journal of organic chemistry. 2016(28)
Enantioenriched, polycyclic compounds were obtained from a simple acylphloroglucinol scaffold. Highly enantioselective dearomatization was accomplished using a Trost ligand-palladium(0) complex. A computational DFT model was developed to rationalize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9142f62c823ecd1c8ec6ab523faa7d47
https://pubmed.ncbi.nlm.nih.gov/28082832
https://pubmed.ncbi.nlm.nih.gov/28082832
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 84
Nitro-containing compounds such as nitrofuran and nitroimidazole are drugs used for the treatment of infectious diseases. However, many of these nitro-containing drugs are positive in the bacterial reverse mutation assay (Ames test). The recently app
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::440eafacf5814dde0552753964dd4cd9
https://pubmed.ncbi.nlm.nih.gov/27988333
https://pubmed.ncbi.nlm.nih.gov/27988333