Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Mikayla Lopes"'
Autor:
Sydney V. Doss, Sébastien Barbat-Artigas, Mikayla Lopes, Bhola Shankar Pradhan, Tomasz J. Prószyński, Richard Robitaille, Gregorio Valdez
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Lynx1 is a glycosylphosphatidylinositol (GPI)-linked protein shown to affect synaptic plasticity through modulation of nicotinic acetylcholine receptor (nAChR) subtypes in the brain. Because of this function and structural similarity to α-bungarotox
Externí odkaz:
https://doaj.org/article/80e0a71b31f8452baeb677df2b839326
Autor:
Ryan Massopust, Devin Juros, Dillon Shapiro, Mikayla Lopes, Saptarsi M. Haldar, Thomas Taetzsch, Gregorio Valdez
Publikováno v:
Neurobiology of Disease, Vol 162, Iss , Pp 105583- (2022)
Amyotrophic Lateral Sclerosis (ALS) is a currently incurable disease that causes progressive motor neuron loss, paralysis and death. Skeletal muscle pathology occurs early during the course of ALS. It is characterized by impaired mitochondrial biogen
Externí odkaz:
https://doaj.org/article/fe367ea0873a4453aa9f1e9a88cad2ac
Autor:
Prajna, Guha, Jillian, Gardell, Benjamin, Rabinowitz, Mikayla, Lopes, Nicholas A, DaSilva, David, Rowley, Steven C, Katz
Publikováno v:
Oncogene. 40(3)
Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of immature myeloid cells that proliferate in the setting of cancer and have potent immunosuppressive functions hindering anti-tumor immunity. Here we establish that the immunolo
Autor:
John C Hardaway, Louis F. Chai, Mikayla Lopes, Benjamin Rabinowitz, Prajna Guha, David Jaroch, Bryan Cox, Robert Knight, Jerome Zeldis, N. Joseph Espat, Steven C Katz
Publikováno v:
The Journal of Immunology. 202:130.1-130.1
Introduction We have demonstrated safety and clinical activity with anti-CEA CAR-T (Sorrento/TNK Therapeutics, Inc.) regional infusions for treatment of liver metastases (LM) using a pressure-enabled drug delivery device (PEDD™, TriSalus™ Life Sc
Publikováno v:
The Journal of Immunology. 200:46.13-46.13
Liver is a tolerogenic organ and has variety of immune cells resulting in a profoundly immunosuppressive space. We recently reported that GM-CSF/JAK2/STAT3 axis drives liver myeloid suppressor cell (L-MDSC) proliferation and STAT3 inhibition causes a