Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Mikayla C. Lopes"'
Publikováno v:
JCI Insight, Vol 8, Iss 9 (2023)
Spinal motor neurons have been implicated in the loss of motor function that occurs with advancing age. However, the cellular and molecular mechanisms that impair the function of these neurons during aging remain unknown. Here, we show that motor neu
Externí odkaz:
https://doaj.org/article/6abe98b8ac37485a8871cf66e168006a
Autor:
Louis F. Chai, John C. Hardaway, Kara R. Heatherton, Kyle P. O’Connell, Mikayla C. Lopes, Benjamin A. Rabinowitz, Chandra C. Ghosh, Prajna Guha, David Jaroch, Bryan F. Cox, Steven C. Katz
Publikováno v:
Vaccines, Vol 9, Iss 8, p 807 (2021)
Metastatic liver tumors have presented challenges with the use of checkpoint inhibitors (CPIs), with only limited success. We hypothesize that regional delivery (RD) of CPIs can improve activity in the liver and minimize systemic exposure, thereby re
Externí odkaz:
https://doaj.org/article/6fb5f456cae4492f8c6c1e505c93455d
Autor:
Louis F. Chai, John C. Hardaway, Kara R. Heatherton, Kyle P. O'Connell, Jason P. LaPorte, Prajna Guha, Mikayla C. Lopes, Benjamin A. Rabinowitz, David Jaroch, Bryan F. Cox, Robert Knight, Steven C. Katz
Publikováno v:
Journal of Surgical Research. 272:37-50
Effective treatment of solid tumors requires multi-modality approaches. In many patients with stage IV liver disease, current treatments are not curative. Chimeric antigen receptor T cells (CAR-T) are an intriguing option following success in hematol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abf869c95ee41bbec7c6820448937aad
https://doi.org/10.1016/j.jss.2021.11.001
https://doi.org/10.1016/j.jss.2021.11.001
Autor:
Mikayla C. Lopes, Nicholas A. DaSilva, Benjamin A. Rabinowitz, Jillian Gardell, Steven C. Katz, David C. Rowley, Prajna Guha
Publikováno v:
Oncogene. 40:693-704
Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of immature myeloid cells that proliferate in the setting of cancer and have potent immunosuppressive functions hindering anti-tumor immunity. Here we establish that the immunolo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11b2fea25fb94fe77ce97f9780648835
https://doi.org/10.1038/s41388-020-01559-7
https://doi.org/10.1038/s41388-020-01559-7
Autor:
Steven C. Katz, Louis F. Chai, Kyle O’Connell, John C. Hardaway, Mikayla C. Lopes, Kara R. Heatherton, Benjamin A. Rabinowitz, David Benjamin Jaroch, Prajna Guha, Chandra C. Ghosh, Bryan Cox
Publikováno v:
Vaccines, Vol 9, Iss 807, p 807 (2021)
Vaccines
Volume 9
Issue 8
Vaccines
Volume 9
Issue 8
Metastatic liver tumors have presented challenges with the use of checkpoint inhibitors (CPIs), with only limited success. We hypothesize that regional delivery (RD) of CPIs can improve activity in the liver and minimize systemic exposure, thereby re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ecf86dc7eca3eebf6d7797e68b3a5b0
https://www.mdpi.com/2076-393X/9/8/807
https://www.mdpi.com/2076-393X/9/8/807
Autor:
Louis F. Chai, John C. Hardaway, Mikayla C. Lopes, Benjamin A. Rabinowitz, Prajna Guha, David Jaroch, Bryan Cox, N. Joseph Espat, Steven C. Katz
Publikováno v:
The Journal of Immunology. 202:71.1-71.1
Introduction Checkpoint inhibitors (CI) have greatly impacted the treatment of solid tumors. Success in the liver has been more limited. When intravenously infused, the CI is delivered predominantly to extrahepatic sites, which results in systemic si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c8dcd93b6d48fc20faf8c5a6049fcd7
https://doi.org/10.4049/jimmunol.202.supp.71.1
https://doi.org/10.4049/jimmunol.202.supp.71.1