Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Mikang Lee"'
Autor:
Ryan Mifflin, Jung Eun Park, Mikang Lee, Prasant Kumar Jena, Yu-Jui Yvonne Wan, Hazel A. Barton, Mirjavid Aghayev, Takhar Kasumov, Li Lin, Xinwen Wang, Robert Novak, Feng Li, He Huang, Leah P. Shriver, Yoon-Kwang Lee
Publikováno v:
Journal of Lipid Research, Vol 64, Iss 12, Pp 100469- (2023)
Deletion of the nuclear hormone receptor small heterodimer partner (Shp) ameliorates the development of obesity and nonalcoholic steatohepatitis (NASH) in mice. Liver-specific SHP plays a significant role in this amelioration. The gut microbiota has
Externí odkaz:
https://doaj.org/article/31e7db3968334b6faf41f7140714318f
Autor:
Yoon-Kwang Lee, Jung Eun Park, Mikang Lee, Ryan Mifflin, Yang Xu, Robert Novak, Yanqiao Zhang, James P. Hardwick
Publikováno v:
Journal of Lipid Research, Vol 64, Iss 11, Pp 100454- (2023)
Small heterodimer partner (SHP, Nr0b2) is an orphan nuclear receptor that regulates bile acid, lipid, and glucose metabolism. Shp−/− mice are resistant to diet-induced obesity and hepatic steatosis. In this study, we explored the potential role o
Externí odkaz:
https://doaj.org/article/29860500e68646c6afe4c0b4d671a4ca
Autor:
Bandar D. Alrehaili, Mikang Lee, Shogo Takahashi, Robert Novak, Bipin Rimal, Shannon Boehme, Samuel A. J. Trammell, Trisha J. Grevengoed, Devendra Kumar, Yazen Alnouti, Katya Chiti, Xinwen Wang, Andrew D. Patterson, John Y. L. Chiang, Frank J. Gonzalez, Yoon‐Kwang Lee
Publikováno v:
Hepatology Communications, Vol 6, Iss 10, Pp 2765-2780 (2022)
Abstract Bile acid‐CoA: amino acid N‐acyltransferase (BAAT) catalyzes bile acid conjugation, the last step in bile acid synthesis. BAAT gene mutation in humans results in hypercholanemia, growth retardation, and fat‐soluble vitamin insufficienc
Externí odkaz:
https://doaj.org/article/d79211ba0cd04455982000fdada5d57f
Publikováno v:
Liver Research, Vol 2, Iss 4, Pp 209-215 (2018)
Peroxisome proliferator-activated receptor gamma (PPARγ or PPARG) is a ligand-activated transcription factor belonging to the nuclear hormone receptor superfamily. It plays a master role in the differentiation and proliferation of adipose tissues. I
Externí odkaz:
https://doaj.org/article/7d714c3e47ab48b18713e22f12ce47de
Publikováno v:
Hepatology Communications. 1:1085-1098
Peroxisome proliferator-activated receptor gamma (PPARγ) is a master regulator for white adipocyte differentiation and lipid storage. The increased level of hepatic PPARγ2 isoform reprograms liver for lipid storage and causes abnormal fat accumulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99be483af7eefc8f237874dd36adeb8a
https://doi.org/10.1002/hep4.1120
https://doi.org/10.1002/hep4.1120
Publikováno v:
Liver research
Liver Research, Vol 2, Iss 4, Pp 209-215 (2018)
Liver Research, Vol 2, Iss 4, Pp 209-215 (2018)
Peroxisome proliferator-activated receptor gamma (PPARγ or PPARG) is a ligand-activated transcription factor belonging to the nuclear hormone receptor superfamily. It plays a master role in the differentiation and proliferation of adipose tissues. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13a57e2769b6989112ec1b5f089c6fd5
https://pubmed.ncbi.nlm.nih.gov/31245168
https://pubmed.ncbi.nlm.nih.gov/31245168
Publikováno v:
The FASEB Journal. 34:1-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::565bb31f8b337671af755588bdc69067
https://doi.org/10.1096/fasebj.2020.34.s1.04864
https://doi.org/10.1096/fasebj.2020.34.s1.04864
Autor:
Jung Eun, Park, Mikang, Lee, Seong-Chul, Kim, Yanqiao, Zhang, James P, Hardwick, Yoon Kwang, Lee
Publikováno v:
Hepatology Communications
Peroxisome proliferator‐activated receptor gamma (PPARγ) is a master regulator for white adipocyte differentiation and lipid storage. The increased level of hepatic PPARγ2 isoform reprograms liver for lipid storage and causes abnormal fat accumul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7582d5052ac81375afd3740a79aebacd
https://pubmed.ncbi.nlm.nih.gov/29404444
https://pubmed.ncbi.nlm.nih.gov/29404444
Publikováno v:
American journal of physiology. Gastrointestinal and liver physiology. 310(10)
Deficiency of the orphan nuclear hormone receptor small heterodimer partner (SHP, NR0B2) protects mice from diet-induced hepatic steatosis, in part, via repression of peroxisome proliferator-activated receptor (PPAR)-γ2( Pparg2) gene expression. Alc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::285a44892514913a3305a0b22cc19193
https://pubmed.ncbi.nlm.nih.gov/26968209
https://pubmed.ncbi.nlm.nih.gov/26968209
Autor:
James P. Hardwick, David Axe, Tiangang Li, Aaron Cook, Yoon Kwang Lee, Mikang Lee, John Y.L. Chiang, Chunki Kim, Seong Chul Kim, Nicole Smallwood, David D. Moore
Publikováno v:
Hepatology (Baltimore, Md.), vol 59, iss 5
SHP, an orphan nuclear hormone receptor, functions as a corepressor and antagonizes coactivator recruitment to target transcription factors with which it interacts (1, 2). Molecular and genetic studies have suggested that SHP also plays a role in obe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e08d576dbe4b2b5deff0f586797e31d
https://escholarship.org/uc/item/61t077c1
https://escholarship.org/uc/item/61t077c1
