Výsledky vyhledávání - "Mikako Miyajima"

Pyridonecarboxylic Acids as Antibacterial Agents. VII. Synthesis and Structure-Activity Relationship of Amino- and Hydroxyl-Substituted 7-Cycloalkyl and 7-Vinyl Derivatives of l-Cyclopropyl-6-fluoro-4- quinolone-3-carboxylic Acid

Autor: Yoshikazu Fukuoka, Yasushi Ikeda, Mikako Miyajima, Yoshiko Yamashiro, Jun Nitta, Yozo Todo, Saikawa Isamu, Hirokazu Narita

Publikováno v: Chemical and Pharmaceutical Bulletin. 42:2055-2062

Novel C(7)-derivatives of 1-cyclopropyl-6-fluoro-4-quinolone carboxylic acid (3a-o) have been synthesized and evaluated for in vitro antibacterial activity. Compounds 3e (3-aminocyclobutyl), 3g (1-aminocyclopropyl), 3m ((2-aminomethyl)vinyl), and 3o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a83991dccd8680e959672cff0efee2ea
https://doi.org/10.1248/cpb.42.2055

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Pyridonecarboxylic acids as antibacterial agents. VIII. Synthesis and structure-activity relationship of 7-(1-aminocyclopropyl)-4-oxo-1,8-naphthyridine-3-carboxylic acids and 7-(1-aminocyclopropyl)-4-oxoquinoline-3-carboxylic acids

Autor: Nagako Nishida, Yozo Todo, Yoshiko Yamashiro, Yoshikazu Fukuoka, Jun Nitta, Saikawa Isamu, Mikako Miyajima, Hirokazu Narita

Publikováno v: Chemicalpharmaceutical bulletin. 42(10)

4-Oxo-1, 8-naphthyridine- and 4-oxoquinoline-3-carboxylic acids (2a, b and 3a-l) possessing a 1-amino-cyclopropyl group at the 7-position have been synthesized and evaluated for in vitro antibacterial activities. The three quinolones (3d, h, i) exhib

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac9f90ec399c15e83645452e66f00ff5
https://pubmed.ncbi.nlm.nih.gov/7805131

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