Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Mikael V. Garabedian"'
Autor:
Mikael V. Garabedian, Zhihui Su, Jorge Dabdoub, Michelle Tong, Alexander Deiters, Daniel A. Hammer, Matthew C. Good
Publikováno v:
Biochemistry
Many proteins harboring low complexity or intrinsically disordered sequences (IDRs) are capable of undergoing liquid-liquid phase separation to form mesoscale condensates that function as biochemical niches with the ability to concentrate or sequeste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c42b77ca5596c5eb198a8010efa07976
https://doi.org/10.1021/acs.biochem.2c00250
https://doi.org/10.1021/acs.biochem.2c00250
Autor:
Rachel M. Welles, Kandarp A. Sojitra, Mikael V. Garabedian, Boao Xia, Roshan M. Regy, Elizabeth R. Gallagher, Jeetain Mittal, Matthew C. Good
Publikováno v:
bioRxiv
Cells harbor numerous mesoscale membraneless compartments that house specific biochemical processes and perform distinct cellular functions. These protein and RNA-rich bodies are thought to form through multivalent interactions among proteins and nuc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1c0cc8546cfeef11b8166d67d16bd5d
https://doi.org/10.1101/2023.03.10.532134
https://doi.org/10.1101/2023.03.10.532134
Autor:
Matthew C. Good, Daniel A. Hammer, Benjamin S. Schuster, Marcel Leutenegger, Muyang Guan, Mikael V Garabedian
Publikováno v:
Biochemistry. 60:3137-3151
Eukaryotic cells partition enzymes and other cellular components into distinct subcellular compartments to generate specialized biochemical niches. A subclass of these compartments form in the absence of lipid membranes, via liquid-liquid phase separ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e297b44ca1f0fc742dacbde71302f17
https://doi.org/10.1021/acs.biochem.1c00373
https://doi.org/10.1021/acs.biochem.1c00373
Autor:
Reese M. Caldwell, Jorge B. Dabdoub, Alexander Deiters, Mikael V Garabedian, Benjamin S. Schuster, Wentao Wang, Michelle Tong, William Benman, Matthew C. Good
Publikováno v:
Nature chemical biology
Subcellular compartmentalization of macromolecules increases flux and prevents inhibitory interactions to control biochemical reactions. Inspired by this functionality, we sought to build designer compartments that function as hubs to regulate the fl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a026b3d25c83b82446fc990984847118
http://europepmc.org/articles/PMC8387445
http://europepmc.org/articles/PMC8387445
Autor:
Anna Vakhrusheva, Alison Wirshing, Bengi Turegun, Mikael V. Garabedian, Olga Sokolova, Bruce L. Goode
Publikováno v:
Molecular Biology of the Cell
Cellular actin arrays are often highly organized, with characteristic patterns critical to their in vivo functions, yet the mechanisms for establishing these higher order geometries remain poorly understood. In Saccharomyces cerevisiae, formin-polyme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48999b2490029d90847fd6d97c891fbe
https://doi.org/10.1091/mbc.e19-12-0693
https://doi.org/10.1091/mbc.e19-12-0693
Autor:
Mikael V. Garabedian, Bruce L. Goode, Luther W. Pollard, Salvatore L. Alioto, Shashank Shekhar
Publikováno v:
Molecular Biology of the Cell. 31:335-347
Yeast actin cables are reconstituted from seven purified proteins, providing a powerful demonstration of how a minimal set of components can self-organize into a micron-scale structure that has many of the same features of actin cables found in vivo.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::424b26f45dfad3599477ed079b01fdfa
https://doi.org/10.1091/mbc.e19-10-0576
https://doi.org/10.1091/mbc.e19-10-0576
Autor:
Muyang, Guan, Mikael V, Garabedian, Marcel, Leutenegger, Benjamin S, Schuster, Matthew C, Good, Daniel A, Hammer
Publikováno v:
Biochemistry
Eukaryotic cells partition enzymes and other cellular components into distinct subcellular compartments to generate specialized biochemical niches. A subclass of these compartments form in the absence of lipid membranes, via liquid-liquid phase separ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e16a8de2eb136941b112327b04e3a304
https://pubmed.ncbi.nlm.nih.gov/34648259
https://pubmed.ncbi.nlm.nih.gov/34648259
Autor:
Luther W, Pollard, Mikael V, Garabedian, Salvatore L, Alioto, Shashank, Shekhar, Bruce L, Goode
Publikováno v:
Molecular Biology of the Cell
A major goal of synthetic biology is to define the minimal cellular machinery required to assemble a biological structure in its simplest form. Here, we focused on Saccharomyces cerevisiae actin cables, which provide polarized tracks for intracellula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e8fe17bd098e0795636b2f16631cafe2
https://pubmed.ncbi.nlm.nih.gov/31913750
https://pubmed.ncbi.nlm.nih.gov/31913750
Autor:
Muyang Guan, Mikael V. Garabedian, Marcel Leutenegger, Benjamin S. Schuster, Matthew C. Good, Daniel A. Hammer
Publikováno v:
Biophysical Journal. 121:146a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5d1c3a482bc8dde7e5c9664c990b1cd
https://doi.org/10.1016/j.bpj.2021.11.1987
https://doi.org/10.1016/j.bpj.2021.11.1987
Autor:
Olga Sokolova, Bruce L. Goode, Chenyu Lou, Thomas J. Rands, Luther W. Pollard, Mikael V. Garabedian, T.B. Stanishneva-Konovalova
Publikováno v:
The Journal of Cell Biology
This study shows that in vivo actin nucleation by the yeast formin Bnr1 is controlled through the coordinated effects of two distinct regulators, a stationary inhibitor (the F-BAR protein Hof1) and a mobile activator (Bud6), establishing a positive f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5170a3cf4766aad885a9dcc9c2089111
http://europepmc.org/articles/PMC6168263
http://europepmc.org/articles/PMC6168263