Zobrazeno 1 - 10
of 137
pro vyhledávání: '"Mikael Rhen"'
Autor:
Johannes A. Eckert, Ming Rosenberg, Mikael Rhen, Ferdinand X. Choong, Agneta Richter-Dahlfors
Publikováno v:
Biofilm, Vol 4, Iss , Pp 100083- (2022)
Antimicrobial resistance is a medical threat of global dimensions. Proper antimicrobial susceptibility testing (AST) for drug development, patient diagnosis and treatment is crucial to counteract ineffective drug use and resistance development. Despi
Externí odkaz:
https://doaj.org/article/5408149d41094f7a99ec787b1a7f589e
Autor:
Kemal Avican, Jehad Aldahdooh, Matteo Togninalli, A. K. M. Firoj Mahmud, Jing Tang, Karsten M. Borgwardt, Mikael Rhen, Maria Fällman
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Bacterial stress responses are potential targets for new antimicrobials. Here, Avican et al. present global transcriptomes for 32 bacterial pathogens grown under 11 stress conditions, and identify common and unique regulatory responses, as well as pr
Externí odkaz:
https://doaj.org/article/528c32ad693d42ecb0d3a057d1175df3
Autor:
Océane C.B. Martin, Anna Bergonzini, Maria Lopez Chiloeches, Eleni Paparouna, Deborah Butter, Sofia D.P. Theodorou, Maria M. Haykal, Elisa Boutet-Robinet, Toma Tebaldi, Andrew Wakeham, Mikael Rhen, Vassilis G. Gorgoulis, Tak Mak, Ioannis S. Pateras, Teresa Frisan
Publikováno v:
Cell Reports, Vol 35, Iss 1, Pp 108931- (2021)
Summary: Bacterial genotoxins cause DNA damage in eukaryotic cells, resulting in activation of the DNA damage response (DDR) in vitro. These toxins are produced by Gram-negative bacteria, enriched in the microbiota of inflammatory bowel disease (IBD)
Externí odkaz:
https://doaj.org/article/09013ccda2564c55996c3bde6c4f4f7d
Autor:
Marie Wrande, Kim Vestö, Speranta Puiac Banesaru, Naeem Anwar, Johan Nordfjell, Lifeng Liu, Gerald M. McInerney, Mikael Rhen
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
Salmonella infection associates with tissue hypoxia, while inducible nitric oxide synthase (iNOS), relying for its activity on molecular oxygen, stands as a central host defence measure in murine salmonellosis. Here, we have detailed hypoxia and iNOS
Externí odkaz:
https://doaj.org/article/6c09376b011647f1b42bed66b82a95b1
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
To successfully colonize a variety of environments, bacteria can coordinate complex collective behaviors such as biofilm formation. To thrive in oxygen limited niches, bacteria’s versatile physiology enables the utilization of alternative electron
Externí odkaz:
https://doaj.org/article/77c0618b160943c3b0d80e18e750998e
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Externí odkaz:
https://doaj.org/article/5c121033b67b4ef9b144d280f6385389
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
The impermeability barrier provided by the outer membrane of enteric bacteria, a feature lacking in Gram-positive bacteria, plays a major role in maintaining resistance to numerous antimicrobial compounds and antibiotics. Here we demonstrate that mut
Externí odkaz:
https://doaj.org/article/f6d29cf1e15448f0922e81b0b98abe36
Autor:
Lisa Del Bel Belluz, Riccardo Guidi, Ioannis S Pateras, Laura Levi, Boris Mihaljevic, Syed Fazle Rouf, Marie Wrande, Marco Candela, Silvia Turroni, Claudia Nastasi, Clarissa Consolandi, Clelia Peano, Toma Tebaldi, Gabriella Viero, Vassilis G Gorgoulis, Thorbjørn Krejsgaard, Mikael Rhen, Teresa Frisan
Publikováno v:
PLoS Pathogens, Vol 12, Iss 4, p e1005528 (2016)
Bacterial genotoxins, produced by several Gram-negative bacteria, induce DNA damage in the target cells. While the responses induced in the host cells have been extensively studied in vitro, the role of these effectors during the course of infection
Externí odkaz:
https://doaj.org/article/8a245ee39f4c44e1858db2eac3f107b9
Publikováno v:
Bio-Protocol, Vol 5, Iss 6 (2015)
The flagellum is required for bacterial swimming and swarming motility. In the biphasic Salmonella enterica serovar Typhimurium (S. Typhimurium), the flagellar filament is build up by two distinct monomeric subunits, flagellin FliC and FljB. S. Typhi
Externí odkaz:
https://doaj.org/article/a8889739567e43848b69f35438174e6f
Autor:
Chee Han Lim, Sabrina Voedisch, Benjamin Wahl, Syed Fazle Rouf, Robert Geffers, Mikael Rhen, Oliver Pabst
Publikováno v:
PLoS Pathogens, Vol 10, Iss 7, p e1004270 (2014)
Vaccination represents an important instrument to control typhoid fever in humans and protects mice from lethal infection with mouse pathogenic serovars of Salmonella species. Mixed infections with tagged Salmonella can be used in combination with pr
Externí odkaz:
https://doaj.org/article/4b971cd5c27547628c9041a5ad0ac452