Zobrazeno 1 - 10
of 149
pro vyhledávání: '"Mikael Hedeland"'
Autor:
Maria Kopsida, Ada Lerma Clavero, Jaafar Khaled, David Balgoma, Clara Luna-Marco, Azazul Chowdhury, Sofi Sennefelt Nyman, Fredrik Rorsman, Charlotte Ebeling Barbier, Peter Bergsten, Hans Lennernäs, Mikael Hedeland, Femke Heindryckx
Publikováno v:
Molecular Metabolism, Vol 79, Iss , Pp 101846- (2024)
Hepatocellular carcinoma (HCC) is characterized by a low and variable response to chemotherapeutic treatments. One contributing factor to the overall pharmacodynamics is the activation of endoplasmic reticulum (ER) stress pathways. This is a cellular
Externí odkaz:
https://doaj.org/article/a28070bb6a72401c97ac140010fab73d
Publikováno v:
BMC Biotechnology, Vol 22, Iss 1, Pp 1-18 (2022)
Abstract Background In the search for methods to biodegrade recalcitrant compounds, the use of saprotrophic fungi and white rot fungi, in particular belonging to the phylum Basidiomycota, has gained interest. This group of fungi possesses a battery o
Externí odkaz:
https://doaj.org/article/1d82af282dcd46e890e802cf84d5509a
Autor:
Vasiliki Koutsouveli, David Balgoma, Antonio Checa, Mikael Hedeland, Ana Riesgo, Paco Cárdenas
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-20 (2022)
Abstract Sponges contain an astounding diversity of lipids that serve in several biological functions, including yolk formation in their oocytes and embryos. The study of lipid metabolism during reproduction can provide information on food-web dynami
Externí odkaz:
https://doaj.org/article/bf4e388a55484d0bb627cd45bce2de58
Autor:
Fredrik Rorsman, Ulrika S H Simonsson, Håkan Ahlström, Sofi Sennefelt Nyman, Angeliki Dimopoulou Creusen, David Dahlgren, Mikael Hedeland, Femke Heindryckx, Ulf Johnson, Jaafar Khaled, Fredrik Kullenberg, Rickard Nyman, Reza Sheikhi, Erik Sjögren, Alkwin Wanders, Hans Lennernäs, Charlotte Ebeling Barbier
Publikováno v:
BMJ Open, Vol 12, Iss 11 (2022)
Introduction Hepatocellular carcinoma (HCC) is a common cause of cancer-related death, often detected in the intermediate stage. The standard of care for intermediate-stage HCC is transarterial chemoembolisation (TACE), where idarubicin (IDA) is a pr
Externí odkaz:
https://doaj.org/article/7c7c91e342a24d6c8b67d590e1e651b2
Autor:
Carl Ekstrand, Peter Michanek, Ronette Gehring, Anna Sundell, Annika Källse, Mikael Hedeland, Lena Ström
Publikováno v:
Frontiers in Veterinary Science, Vol 9 (2022)
IntroductionAtropine is an essential part of the treatment protocol for equine uveitis. Topical atropine administration has been associated with decreased intestinal motility and abdominal pain in horses. Experimental studies have indicated that freq
Externí odkaz:
https://doaj.org/article/0b42a5ef270443bd8dd9791e914f0518
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 6, Pp 1667-1675 (2021)
Transcellular permeation enhancers are known to increase the intestinal permeability of enalaprilat, a 349 Da peptide, but not hexarelin (887 Da). The primary aim of this paper was to investigate if paracellular permeability enhancers affected the in
Externí odkaz:
https://doaj.org/article/1df137de4b5d48ac9f4b8ee8b610534f
Publikováno v:
Environmental Advances, Vol 8, Iss , Pp 100194- (2022)
The internal concentrations of active pharmaceutical compounds in insects/macroinvertebrates in River Fyris, Uppsala, Sweden, have for the first time been investigated. Specimen of backswimmer, caddisfly larva, damselfly larva, mayfly larva and water
Externí odkaz:
https://doaj.org/article/49b7cca661bd44d092884b94c412b8e0
Autor:
Raad Askar, Elin Fredriksson, Elin Manell, Mikael Hedeland, Ulf Bondesson, Simon Bate, Lena Olsén, Patricia Hedenqvist
Publikováno v:
BMC Veterinary Research, Vol 16, Iss 1, Pp 1-10 (2020)
Abstract Background Buprenorphine is one of the most used analgesics for postoperative pain in rabbits. The recommended dose in rabbits (0.01–0.05 mg/kg) is the same for intravenous (IV), intramuscular (IM), and subcutaneous (SC) administration, de
Externí odkaz:
https://doaj.org/article/452c9858384441f59c2334ae85f7131b
Autor:
David Balgoma, Fredrik Kullenberg, Karsten Peters, David Dahlgren, Femke Heindryckx, Hans Lennernäs, Mikael Hedeland
Publikováno v:
Metabolites, Vol 12, Iss 9, p 866 (2022)
Ad libitum feeding of experimental animals is preferred because of medical relevance together with technical and practical considerations. In addition, ethical committees may require ad libitum feeding. However, feeding affects the metabolism so ad l
Externí odkaz:
https://doaj.org/article/b796cac483c148ec8ada85f1173c28ac
Autor:
Carl Ekstrand, Helena Pettersson, Ronette Gehring, Mikael Hedeland, Sara Adolfsson, Inger Lilliehöök
Publikováno v:
Frontiers in Veterinary Science, Vol 8 (2021)
Glucocorticoids such as prednisolone are commonly used in dogs but there is sparse quantitative pharmacokinetic and pharmacodynamic information of this drug in this species. The objective of this study was to quantitatively characterize the concentra
Externí odkaz:
https://doaj.org/article/d5fbe4b3d572448fa576d280d06865eb