Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Mikael E Sellin"'
Autor:
Chantal Ernst, Patrick R Andreassen, Gabriel H Giger, Bidong D Nguyen, Christoph G Gäbelein, Orane Guillaume-Gentil, Stefan A Fattinger, Mikael E Sellin, Wolf-Dietrich Hardt, Julia A Vorholt
Publikováno v:
PLoS Biology, Vol 22, Iss 4, p e3002597 (2024)
Intestinal epithelial cells (IECs) play pivotal roles in nutrient uptake and in the protection against gut microorganisms. However, certain enteric pathogens, such as Salmonella enterica serovar Typhimurium (S. Tm), can invade IECs by employing flage
Externí odkaz:
https://doaj.org/article/be0194b104fc4fb58354f7d0ece570b5
Autor:
Ersin Gül, Ursina Enz, Luca Maurer, Andrew Abi Younes, Stefan A Fattinger, Bidong D Nguyen, Annika Hausmann, Markus Furter, Manja Barthel, Mikael E Sellin, Wolf-Dietrich Hardt
Publikováno v:
PLoS Pathogens, Vol 19, Iss 6, p e1011235 (2023)
Recruitment of neutrophils into and across the gut mucosa is a cardinal feature of intestinal inflammation in response to enteric infections. Previous work using the model pathogen Salmonella enterica serovar Typhimurium (S.Tm) established that invas
Externí odkaz:
https://doaj.org/article/eba57bd740684b71a7c87e04baa65b1d
Autor:
Jana Grüttner, Jorik M van Rijn, Petra Geiser, Alexandra Florbrant, Dominic-Luc Webb, Per M Hellström, Magnus Sundbom, Mikael E Sellin, Staffan G Svärd
Publikováno v:
PLoS Pathogens, Vol 19, Iss 5, p e1011372 (2023)
Giardia intestinalis is a non-invasive, protozoan parasite infecting the upper small intestine of most mammals. Symptomatic infections cause the diarrhoeal disease giardiasis in humans and animals, but at least half of the infections are asymptomatic
Externí odkaz:
https://doaj.org/article/3866db1585db48c6b9094dcf066e570e
Autor:
Christopher von Beek, Linnéa Alriksson, Josefine Palle, Ann-Marie Gustafson, Mirjana Grujic, Fabio Rabelo Melo, Mikael E Sellin, Gunnar Pejler
Publikováno v:
PLoS ONE, Vol 16, Iss 9, p e0256708 (2021)
Current chemotherapy for treatment of pediatric acute leukemia, although generally successful, is still a matter of concern due to treatment resistance, relapses and life-long side effects for a subset of patients. Inhibition of dynamin, a GTPase inv
Externí odkaz:
https://doaj.org/article/5b614d18e45a4f0386467264e671f2aa
Autor:
Stefan A Fattinger, Desirée Böck, Maria Letizia Di Martino, Sabrina Deuring, Pilar Samperio Ventayol, Viktor Ek, Markus Furter, Saskia Kreibich, Francesco Bosia, Anna A Müller-Hauser, Bidong D Nguyen, Manfred Rohde, Martin Pilhofer, Wolf-Dietrich Hardt, Mikael E Sellin
Publikováno v:
PLoS Pathogens, Vol 16, Iss 5, p e1008503 (2020)
Salmonella enterica serovar Typhimurium (S.Tm) infections of cultured cell lines have given rise to the ruffle model for epithelial cell invasion. According to this model, the Type-Three-Secretion-System-1 (TTSS-1) effectors SopB, SopE and SopE2 driv
Externí odkaz:
https://doaj.org/article/5a9d7e06a10540bb8d6ba0e1370f2e5b
Autor:
Anna A Müller, Tamas Dolowschiak, Mikael E Sellin, Boas Felmy, Carolin Verbree, Sandra Gadient, Alexander J Westermann, Jörg Vogel, Salome LeibundGut-Landmann, Wolf-Dietrich Hardt
Publikováno v:
PLoS Pathogens, Vol 12, Iss 6, p e1005723 (2016)
Salmonella Typhimurium (S.Tm) is a common cause of self-limiting diarrhea. The mucosal inflammation is thought to arise from a standoff between the pathogen's virulence factors and the host's mucosal innate immune defenses, particularly the mucosal N
Externí odkaz:
https://doaj.org/article/6de70c34ee27416d9a88afee586df5a5
Autor:
Lisa Maier, Médéric Diard, Mikael E Sellin, Elsa-Sarah Chouffane, Kerstin Trautwein-Weidner, Balamurugan Periaswamy, Emma Slack, Tamas Dolowschiak, Bärbel Stecher, Claude Loverdo, Roland R Regoes, Wolf-Dietrich Hardt
Publikováno v:
PLoS Pathogens, Vol 11, Iss 7, p e1005047 (2015)
Externí odkaz:
https://doaj.org/article/6569d1eb80894164910054598146634c
Autor:
Lisa Maier, Médéric Diard, Mikael E Sellin, Elsa-Sarah Chouffane, Kerstin Trautwein-Weidner, Balamurugan Periaswamy, Emma Slack, Tamas Dolowschiak, Bärbel Stecher, Claude Loverdo, Roland R Regoes, Wolf-Dietrich Hardt
Publikováno v:
PLoS Pathogens, Vol 10, Iss 12, p e1004557 (2014)
Topological, chemical and immunological barriers are thought to limit infection by enteropathogenic bacteria. However, in many cases these barriers and their consequences for the infection process remain incompletely understood. Here, we employed a m
Externí odkaz:
https://doaj.org/article/87617370f0ca4d6683661f9ffcbaa03d
Autor:
Kristoffer Brännström, Malin Lindhagen-Persson, Anna L Gharibyan, Irina Iakovleva, Monika Vestling, Mikael E Sellin, Thomas Brännström, Ludmilla Morozova-Roche, Lars Forsgren, Anders Olofsson
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e90857 (2014)
Antibodies that preferentially and specifically target pathological oligomeric protein and peptide assemblies, as opposed to their monomeric and amyloid counterparts, provide therapeutic and diagnostic opportunities for protein misfolding diseases. U
Externí odkaz:
https://doaj.org/article/85bdb2aa8c704054b936e00b43b5987b
Autor:
Sara E Thorslund, Tomas Edgren, Jonas Pettersson, Roland Nordfelth, Mikael E Sellin, Ekaterina Ivanova, Matthew S Francis, Elin L Isaksson, Hans Wolf-Watz, Maria Fällman
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e16784 (2011)
Many gram-negative bacteria use type III secretion systems to translocate effector proteins into host cells. These effectors interfere with cellular functions in a highly regulated manner resulting in effects that are beneficial for the bacteria. The
Externí odkaz:
https://doaj.org/article/f8575204e05b413b8a943f5318ca02bc