Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Mikael Dohlsten"'
Publikováno v:
European Journal of Haematology. 60:233-239
Bacterial superantigens (SAgs) bound to MHC class II molecules on target cells are efficient activators of cytotoxic T cells expressing certain T cell receptor (TCR) Vbeta regions We described earlier that the specificity of the SAg Staphylococcus en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b54020839ddd2d1a7d92e6ea1c42f7d
https://doi.org/10.1111/j.1600-0609.1998.tb01029.x
https://doi.org/10.1111/j.1600-0609.1998.tb01029.x
Publikováno v:
Scandinavian Journal of Haematology. 32:113-118
Fluoresceinated human albumin conjugated with histamine (FHA-HIS) has been used for the demonstration of histamine receptors on human platelets. Such receptors were demonstrated on 40-63% of peripheral blood platelets in 4 healthy donors. The binding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::623b173d087bfb3e0da67301488722d9
https://doi.org/10.1111/j.1600-0609.1984.tb02165.x
https://doi.org/10.1111/j.1600-0609.1984.tb02165.x
Autor:
David M Shaw, Mikael Dohlsten, P Björk, Lennart Ohlsson, Peter L. Stern, P A Lando, Thomas Brodin, Göran Forsberg
Publikováno v:
British Journal of Cancer
Superantigens activate T-cells by linking the T-cell receptor to MHC class II on antigen-presenting cells, and novel reactivity can be introduced by fusing the superantigen to a targeting molecule. Thus, an antibody-targeted superantigen, which activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4826322185fc2f788e4254652bf996e5
http://europepmc.org/articles/PMC2363924
http://europepmc.org/articles/PMC2363924
Publikováno v:
Cancer Gene Therapy. 7:1365-1374
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aec4fd63ca2ec032ed0830606e66762f
https://doi.org/10.1038/sj.cgt.0242
https://doi.org/10.1038/sj.cgt.0242
Publikováno v:
Cancer Gene Therapy. 7:1365-1374
We have demonstrated previously that gene transfer of the mature human interleukin-1beta (IL-1beta) gene, fused to a signal sequence (ss), into mouse B16 melanoma cells results in an inhibition of their growth in vivo compared with control B16 cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4da0284c7e075f0df6f7d73fa5a221b5
https://doi.org/10.1038/sj.cgt.7700248
https://doi.org/10.1038/sj.cgt.7700248
Publikováno v:
International Immunology. 12:253-261
We have recently described the novel A6H antigen expressed on human peripheral blood T cells and on renal cell carcinoma cells. Cross-linking of the A6H antigen results in co-stimulation of human CD4(+) T cells, characterized by induction of the tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::675d70a0ba1d998df77622f5d85f3605
https://doi.org/10.1093/intimm/12.3.253
https://doi.org/10.1093/intimm/12.3.253
Publikováno v:
The Journal of Immunology. 164:1175-1184
Repeated administration of the superantigen staphylococcal enterotoxin A to mice transduces a state of anergy in the CD4+ T cell compartment, characterized by inhibition of IL-2 production and clonal expansion in vivo. In contrast to what has been re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a483f556217047f6a3714e32730bf839
https://doi.org/10.4049/jimmunol.164.3.1175
https://doi.org/10.4049/jimmunol.164.3.1175
Autor:
Karin Kristensson, Mats Carlsson, Niels Jørgen Skartved, Morten Søgaard, Kristian Riesbeck, Alexander Rosendahl, Mikael Dohlsten
Publikováno v:
International Journal of Cancer. 81:156-163
The bacterial superantigen (SAg) staphylococcal enterotoxin A (SEA) is a potent inducer of CTL activity and cytokine production in vivo. To engineer SAg for cancer immunotherapy, we genetically fused SEA to a Fab fragment of the C215 tumor-reactive a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b60b9d6a9b0d7fb270ffcf2b0dd945ad
https://doi.org/10.1002/(sici)1097-0215(19990331)81:1<156::aid-ijc25>3.0.co
https://doi.org/10.1002/(sici)1097-0215(19990331)81:1<156::aid-ijc25>3.0.co
Publikováno v:
International Immunology. 11:427-433
We have recently described the A6H antigen as a novel 120-140 kDa molecule which is co-expressed on human peripheral blood T cells and renal cell carcinoma cells. Engagement of the A6H antigen results in co-stimulation of CD4+ T cells but it remained
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac2ffca72a8577d45d00ada08659e602
https://doi.org/10.1093/intimm/11.3.427
https://doi.org/10.1093/intimm/11.3.427
Autor:
Niels Ødum, Jens Gerwien, Mikael Dohlsten, S. Thulesen, Carsten Röpke, A. Jørgensen, M. Holst Nissen
Publikováno v:
Experimental and Clinical Immunogenetics. 16:226-233
A high percentage of human fetal and postnatal thymocytes express MHC class II molecules. This raises the possibility that human thymocytes in early life are able to present peptides to other immature T cells and thereby initiate thymic selection of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d06646e75cfbec0a97bf0b6b0d20d91
https://doi.org/10.1159/000019114
https://doi.org/10.1159/000019114