Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Mikael C. Guzman-Karlsson"'
Autor:
Andrew J. Kennedy, Elizabeth J. Rahn, Brynna S. Paulukaitis, Katherine E. Savell, Holly B. Kordasiewicz, Jing Wang, John W. Lewis, Jessica Posey, Sarah K. Strange, Mikael C. Guzman-Karlsson, Scott E. Phillips, Kyle Decker, S. Timothy Motley, Eric E. Swayze, David J. Ecker, Todd P. Michael, Jeremy J. Day, J. David Sweatt
Publikováno v:
Cell Reports, Vol 16, Iss 10, Pp 2666-2685 (2016)
Human haploinsufficiency of the transcription factor Tcf4 leads to a rare autism spectrum disorder called Pitt-Hopkins syndrome (PTHS), which is associated with severe language impairment and development delay. Here, we demonstrate that Tcf4 haploins
Externí odkaz:
https://doaj.org/article/b3ced49ba885434ea78334ce9770d0f4
Autor:
Kyle Decker, Holly B. Kordasiewicz, Katherine E. Savell, Jessica L. Posey, Elizabeth J. Rahn, Brynna S. Paulukaitis, Andrew J. Kennedy, David J. Ecker, Mikael C. Guzman-Karlsson, John W. Lewis, S. Timothy Motley, J. David Sweatt, Jing Wang, Todd P. Michael, Eric E. Swayze, Jeremy J. Day, Sarah K. Strange, Scott E. Phillips
Publikováno v:
Cell Reports, Vol 16, Iss 10, Pp 2666-2685 (2016)
Summary Human haploinsufficiency of the transcription factor Tcf4 leads to a rare autism spectrum disorder called Pitt-Hopkins syndrome (PTHS), which is associated with severe language impairment and development delay. Here, we demonstrate that Tcf4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc4f89f28b335426c4655b7c951c00eb
https://doi.org/10.1016/j.celrep.2016.08.004
https://doi.org/10.1016/j.celrep.2016.08.004
Autor:
Scott E. Phillips, Mikael C. Guzman-Karlsson, John J. Hablitz, Jordan A. Brown, Sarah K. Strange, Jarrod P. Meadows, J. David Sweatt
Epigenetic modifications, such as DNA cytosine methylation, contribute to the mechanisms underlying learning and memory by coordinating adaptive gene expression and neuronal plasticity. Transcription-dependent plasticity regulated by DNA methylation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::561cb35ac73f2a76f28532d5d91351bf
https://europepmc.org/articles/PMC5709999/
https://europepmc.org/articles/PMC5709999/
Autor:
Cassie Holleman, J. David Sweatt, Jarrod P. Meadows, Scott E. Phillips, Mikael C. Guzman-Karlsson, Jessica L. Posey, John J. Hablitz, Jeremy J. Day
Publikováno v:
Science Signaling. 8
Enhanced receptiveness at all synapses on a neuron that receive glutamatergic input is called cell-wide synaptic upscaling. We hypothesize that this type of synaptic plasticity may be critical for long-term memory storage within cortical circuits, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22eec339e9e2ac657c4f84e5a2dfbe63
https://doi.org/10.1126/scisignal.aab0715
https://doi.org/10.1126/scisignal.aab0715
Autor:
J. David Sweatt, Mikael C. Guzman-Karlsson, Cristin F. Gavin, Jarrod P. Meadows, John J. Hablitz
The epigenome is uniquely positioned as a point of convergence, integrating multiple intracellular signaling cascades into a cohesive gene expression profile necessary for long-term behavioral change. The last decade of neuroepigenetic research has p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a18035f4eef04edb85a9d7800b1301f6
https://europepmc.org/articles/PMC3984596/
https://europepmc.org/articles/PMC3984596/
Autor:
Thomas Rogerson, Balaji Jayaprakash, Brian J. Wiltgen, Mikael C. Guzman-Karlsson, Rafał Czajkowski, Joshua T. Trachtenberg, Alcino J. Silva, Alison L. Barth
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 111, iss 23
The retrosplenial cortex (RSC) is part of a network of interconnected cortical, hippocampal, and thalamic structures harboring spatially modulated neurons. The RSC contains head direction cells and connects to the parahippocampal region and anterior
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::188a32dc78b7ded7f1beadfdeaec4753
Sensitization is a form of non-associative conditioning in which amplification of behavioral responses can occur following presentation of an aversive or noxious stimulus. Understanding the cellular and molecular underpinnings of sensitization has be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::491781abfff1403e2734e7ee56bbffec
https://europepmc.org/articles/PMC3769437/
https://europepmc.org/articles/PMC3769437/
Autor:
J. David Sweatt, Mikael C. Guzman-Karlsson, Daniel Childs, Jerome Moulden, Absar Tahir, Esther Y. Song, Mercy Kibe, Jeremy J. Day
Publikováno v:
Nature neuroscience
Reward-related memories are essential for adaptive behavior and evolutionary fitness, but they are also a core component of maladaptive brain diseases such as addiction. Reward learning requires dopamine neurons located in the ventral tegmental area
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d5b192f8cb7d7fba0895125157a0ea5
https://pubmed.ncbi.nlm.nih.gov/23974711
https://pubmed.ncbi.nlm.nih.gov/23974711
Publikováno v:
Learningmemory (Cold Spring Harbor, N.Y.). 20(2)
Understanding the cellular and molecular mechanisms underlying the formation and maintenance of memories is a central goal of the neuroscience community. It is well regarded that an organism's ability to lastingly adapt its behavior in response to a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aea4397834951a38ffad18041f37bf51
https://pubmed.ncbi.nlm.nih.gov/23322554
https://pubmed.ncbi.nlm.nih.gov/23322554