Zobrazeno 1 - 10
of 112
pro vyhledávání: '"Mikael C I Karlsson"'
Autor:
Yunying Chen, Sara Lind Enoksson, Catharina Johansson, Maria A Karlsson, Lena Lundeberg, Gunnar Nilsson, Annika Scheynius, Mikael C I Karlsson
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22202 (2011)
The TNF family cytokines BAFF (B-cell activating factor of the TNF family) and APRIL (a proliferation-inducing ligand) are crucial survival factors for B-cell development and activation. B-cell directed treatments have been shown to improve atopic ec
Externí odkaz:
https://doaj.org/article/ec710accced348eb97bf664179f20662
Autor:
Anna S. Wilhelmson, Inger Johansson, Linda Fogelstrand, Johan Bourghardt Fagman, Jean-Francois Arnal, Mikael C. I. Karlsson, Åsa Tivesten
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-6 (2022)
Abstract Testosterone deficiency in men is associated with increased atherosclerosis burden and increased cardiovascular risk. In male mice, testosterone deficiency induced by castration increases atherosclerosis as well as mature B cell numbers in s
Externí odkaz:
https://doaj.org/article/65d58c0ac98f437c848030b1574124b7
Autor:
Luuk van Hooren, Alessandra Vaccaro, Mohanraj Ramachandran, Konstantinos Vazaios, Sylwia Libard, Tiarne van de Walle, Maria Georganaki, Hua Huang, Ilkka Pietilä, Joey Lau, Maria H. Ulvmar, Mikael C. I. Karlsson, Maria Zetterling, Sara M. Mangsbo, Asgeir S. Jakola, Thomas Olsson Bontell, Anja Smits, Magnus Essand, Anna Dimberg
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Agonistic CD40 antibodies (αCD40) have broad immunostimulatory properties, however their efficacy in glioma remains unclear. Here the authors show that αCD40 promotes the formation of tertiary lymphoid structures but does not improve survival and i
Externí odkaz:
https://doaj.org/article/960c23767579410eb75556847b8c9b3f
Autor:
Anita Kumari, Judith Pineau, Pablo J. Sáez, Mathieu Maurin, Danielle Lankar, Mabel San Roman, Katharina Hennig, Vanessa F. Boura, Raphael Voituriez, Mikael C. I. Karlsson, Martial Balland, Ana-Maria Lennon Dumenil, Paolo Pierobon
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
The immune synapse promotes cellular information exchange but the role of biophysical forces in synapse function is unclear. Here, the authors show that B cells exert two types of forces, a centripetal myosin II-driven force and a central actin protr
Externí odkaz:
https://doaj.org/article/153dc305ef9a4480872d0c78f10b8923
Autor:
Anna S. Wilhelmson, Marta Lantero Rodriguez, Alexandra Stubelius, Per Fogelstrand, Inger Johansson, Matthew B. Buechler, Steve Lianoglou, Varun N. Kapoor, Maria E. Johansson, Johan B. Fagman, Amanda Duhlin, Prabhanshu Tripathi, Alessandro Camponeschi, Bo T. Porse, Antonius G. Rolink, Hans Nissbrandt, Shannon J. Turley, Hans Carlsten, Inga-Lill Mårtensson, Mikael C. I. Karlsson, Åsa Tivesten
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Testosterone deficiency is associated with autoimmunity and increased B cell numbers, but the underlying mechanism is unclear. Here the authors show that testosterone may modulate the production of B cell survival factor BAFF by fibroblastic reticula
Externí odkaz:
https://doaj.org/article/d1f804563c204b959332c0cb6ac7f78d
Autor:
Saikiran K. Sedimbi, David P. Lane, Marika Nestor, Fredrik Wermeling, Mikael C. I. Karlsson, Eduardo J. Villablanca, Nicolas Fritz, Omayma Al-Radi, Warren W. Kretzschmar, Cecilia Bosdotter, Francisca Castillo, Dilraj Lama, Danai Lianoudaki, Silke Eisinger, Long Jiang, Jessica Hacheney, Linnéa Påvénius, Pavitra Kannan, Diana Spiegelberg, Katrine Ingelshed
Proteomics data.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c11d2af10f59413e8f1e955c8d5ca61d
https://doi.org/10.1158/2767-9764.22545455.v1
https://doi.org/10.1158/2767-9764.22545455.v1
Autor:
Saikiran K. Sedimbi, David P. Lane, Marika Nestor, Fredrik Wermeling, Mikael C. I. Karlsson, Eduardo J. Villablanca, Nicolas Fritz, Omayma Al-Radi, Warren W. Kretzschmar, Cecilia Bosdotter, Francisca Castillo, Dilraj Lama, Danai Lianoudaki, Silke Eisinger, Long Jiang, Jessica Hacheney, Linnéa Påvénius, Pavitra Kannan, Diana Spiegelberg, Katrine Ingelshed
B16-F10 +/+ cells treated with increasing Navtemadlin concentrations over time.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::846a646e71ea345f4ade6100d14e1d12
https://doi.org/10.1158/2767-9764.22545482
https://doi.org/10.1158/2767-9764.22545482
Autor:
Saikiran K. Sedimbi, David P. Lane, Marika Nestor, Fredrik Wermeling, Mikael C. I. Karlsson, Eduardo J. Villablanca, Nicolas Fritz, Omayma Al-Radi, Warren W. Kretzschmar, Cecilia Bosdotter, Francisca Castillo, Dilraj Lama, Danai Lianoudaki, Silke Eisinger, Long Jiang, Jessica Hacheney, Linnéa Påvénius, Pavitra Kannan, Diana Spiegelberg, Katrine Ingelshed
The tumor suppressor protein p53 is mutated in close to 50% of human tumors and is dysregulated in many others, for instance by silencing or loss of p14ARF. Under steady-state conditions, the two E3 ligases MDM2/MDM4 interact with and inhibit the tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::000188325df54f8c15797ee060e15664
https://doi.org/10.1158/2767-9764.c.6550949.v1
https://doi.org/10.1158/2767-9764.c.6550949.v1
Autor:
Saikiran K. Sedimbi, David P. Lane, Marika Nestor, Fredrik Wermeling, Mikael C. I. Karlsson, Eduardo J. Villablanca, Nicolas Fritz, Omayma Al-Radi, Warren W. Kretzschmar, Cecilia Bosdotter, Francisca Castillo, Dilraj Lama, Danai Lianoudaki, Silke Eisinger, Long Jiang, Jessica Hacheney, Linnéa Påvénius, Pavitra Kannan, Diana Spiegelberg, Katrine Ingelshed
Complete list of proteins.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::029707c1d6bcf34612f00c36c04b3e48
https://doi.org/10.1158/2767-9764.22545458.v1
https://doi.org/10.1158/2767-9764.22545458.v1
Autor:
Marisa A. P. Baptista, Marton Keszei, Mariana Oliveira, Karen K. S. Sunahara, John Andersson, Carin I. M. Dahlberg, Austen J. Worth, Agne Liedén, I-Chun Kuo, Robert P. A. Wallin, Scott B. Snapper, Liv Eidsmo, Annika Scheynius, Mikael C. I. Karlsson, Gerben Bouma, Siobhan O. Burns, Mattias N. E. Forsell, Adrian J. Thrasher, Susanne Nylén, Lisa S. Westerberg
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
Wiskott–Aldrich syndrome (WAS) is a severe X-linked primary immunodeficiency syndrome. Here, the authors show that loss of WAS gene in dendritic cells results in increased activity of Rac2, increase of phagosomal pH, and more efficient cross-presen
Externí odkaz:
https://doaj.org/article/b30cb5531b534a4c9f3e0c5bebf69da8