Zobrazeno 1 - 10
of 128
pro vyhledávání: '"Mikael Björnstedt"'
Autor:
Ali Razaghi, Mikael Björnstedt
Publikováno v:
Cancers, Vol 16, Iss 13, p 2382 (2024)
Selenoprotein P (SELENOP) acts as a crucial mediator, distributing selenium from the liver to other tissues within the body. Despite its established role in selenium metabolism, the specific functions of SELENOP in the development of liver cancer rem
Externí odkaz:
https://doaj.org/article/dc40a2b60a4147bb895b87171e74da62
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
PD-1 and PD-L1 are crucial regulators of immunity expressed on the surface of T cells and tumour cells, respectively. Cancer cells frequently use PD-1/PD-L1 to evade immune detection; hence, blocking them exposes tumours to be attacked by activated T
Externí odkaz:
https://doaj.org/article/4ec5851958784f21a6bfc09c2d2cd5d6
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 10, Pp 1059-1068 (2021)
Interferon (IFN) therapy has been the standard of care for a variety of cancers for decades due to the pleiotropic actions of IFNs against malignancies. However, little is known about the role of copy number alteration (CNA) of the IFN gene cluster,
Externí odkaz:
https://doaj.org/article/65386198310f41b1b20c713be1c97fb3
Autor:
Carlos Fernández Moro, Arun Kumar Selvam, Mehran Ghaderi, Ville N. Pimenoff, Marco Gerling, Béla Bozóky, Soledad Pouso Elduayen, Joakim Dillner, Mikael Björnstedt
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Pancreatic ductal adenocarcinoma (PDAC) is the most common type of pancreatic cancer. PDAC has a dismal prognosis and an inherent resistance to cytostatic drugs. The lack of reliable experimental models is a severe limitation for drug development tar
Externí odkaz:
https://doaj.org/article/eb1992e46a424f3fbb7f5de9bc7d35fa
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
A high expression level of programmed death-ligand 1 (PD-L1) is observed in different types of cancers (particularly lung cancer). Soluble (s)PD-L1 may be used as a prognostic marker and a target for anti-cancer immunity, as well as, predicting gene
Externí odkaz:
https://doaj.org/article/b8e65a93cd0845f6866f9a562ada0315
Publikováno v:
International Journal of Infectious Diseases, Vol 110, Iss , Pp 433-435 (2021)
Objectives: The aim of this study was to estimate how well the excess mortality reflected the burden of coronavirus disease 2019 (COVID-19)-related deaths during the March–May 2020 COVID-19 outbreak in Stockholm, Sweden, and whether the excess mort
Externí odkaz:
https://doaj.org/article/f022edec0d964d27abf98a32a9685289
Publikováno v:
Biomedicines, Vol 11, Iss 2, p 295 (2023)
Cancer is one of the main causes of human death globally and novel chemotherapeutics are desperately required. As a simple selenium oxide, selenite is a very promising chemotherapeutic because of pronounced its dose-dependent tumor-specific cytotoxic
Externí odkaz:
https://doaj.org/article/5fdb59cda90c401abd4641a38aa59b7e
Autor:
Jan C. Kamp, Naomi N. Kappe, Carlos Fernández Moro, Jan Fuge, Mark P. Kuehnel, Sabine Wrenger, Tobias Welte, Bart van Hoek, Danny D. Jonigk, Padmini P. S. J. Khedoe, Pavel Strnad, Mikael Björnstedt, Jan Stolk, Sabina Janciauskiene, Antal Nemeth
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 3, p 2485 (2023)
PiZZ (Glu342Lys) α1-antitrypsin deficiency (AATD) is characterized by intrahepatic AAT polymerization and is a risk factor for liver disease development in children. The majority of PiZZ children are disease free, hence this mutation alone is not su
Externí odkaz:
https://doaj.org/article/fb5fa1378f564aad8da606ca073c7635
Autor:
Tímea Szekerczés, Arun Kumar Selvam, Carlos Fernández Moro, Soledad Pouso Elduayen, Joakim Dillner, Mikael Björnstedt, Mehran Ghaderi
Publikováno v:
Antioxidants, Vol 12, Iss 1, p 167 (2023)
Patient-derived tissue culture models are valuable tools to investigate drug effects and targeted treatment approaches. Resected tumor slices cultured ex vivo have recently gained interest in precision medicine, since they reflect the complex microen
Externí odkaz:
https://doaj.org/article/c7ee6b00f8b6433d815adca6369bc29f
Publikováno v:
Diagnostics, Vol 12, Iss 11, p 2789 (2022)
Critically ill COVID-19 patients with pleural effusion experience longer hospitalization, multisystem inflammatory syndrome, and higher rates of mortality. Generally, pleural effusion can serve as a diagnostic value to differentiate cytokine levels.
Externí odkaz:
https://doaj.org/article/5b062f662d7c4044af35e915ceecb864