Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Mikael Björklund"'
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)
Abstract How organisms maintain cell size homeostasis is a long-standing problem that remains unresolved, especially in multicellular organisms. Recent experiments in diverse animal cell types demonstrate that within a cell population, cellular proli
Externí odkaz:
https://doaj.org/article/1df57102af1448cf878237b0ee1a021c
Autor:
Xudong Yao, Yuanzhu Ma, Wenyan Zhou, Youguo Liao, Zongsheng Jiang, Junxin Lin, Qiulin He, Hongwei Wu, Wei Wei, Xiaozhao Wang, Mikael Björklund, Hongwei Ouyang
Publikováno v:
Bioengineering & Translational Medicine, Vol 7, Iss 1, Pp n/a-n/a (2022)
Abstract Stem cell therapies are unsatisfactory due to poor cell survival and engraftment. Stem cell used for therapy must be properly “tuned” for a harsh in vivo environment. Herein, we report that transfer of exogenous mitochondria (mito) to ad
Externí odkaz:
https://doaj.org/article/296c6e40c0c34d79b94a48a43c918916
Autor:
Yasen Maimaitiyiming, Tao Yang, Qian Qian Wang, Yan Feng, Zhi Chen, Mikael Björklund, Fudi Wang, Chonggao Hu, Chih-Hung Hsu, Hua Naranmandura
Publikováno v:
Research, Vol 2022 (2022)
Despite extensive efforts, COVID-19 pandemic caused by the SARS-CoV-2 virus is still at large. Vaccination is an effective approach to curb virus spread, but several variants (e.g., delta, delta plus, omicron, and IHU) appear to weaken or possibly es
Externí odkaz:
https://doaj.org/article/3fa9fcaf20c6481a94232b610a9dd34e
Autor:
Teemu P. Miettinen, Mikael Björklund
Publikováno v:
Cell Reports, Vol 13, Iss 11, Pp 2610-2620 (2015)
Balance between cell growth and proliferation determines cell size homeostasis, but little is known about how metabolic pathways are involved in the maintenance of this balance. Here, we perform a screen with a library of clinically used drug molecul
Externí odkaz:
https://doaj.org/article/610cad1fd68148c793b123bf2d4d45ad
Autor:
Johannes Bischof, Marilyne Duffraisse, Edy Furger, Leiore Ajuria, Guillaume Giraud, Solene Vanderperre, Rachel Paul, Mikael Björklund, Damien Ahr, Alexis W Ahmed, Lionel Spinelli, Christine Brun, Konrad Basler, Samir Merabet
Publikováno v:
eLife, Vol 7 (2018)
Transcription factors achieve specificity by establishing intricate interaction networks that will change depending on the cell context. Capturing these interactions in live condition is however a challenging issue that requires sensitive and non-inv
Externí odkaz:
https://doaj.org/article/4f3279d94fd944efacc4d7695842697f
Autor:
Mikael Björklund, Samuel Marguerat
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 5 (2017)
Externí odkaz:
https://doaj.org/article/f06a08437269421a89873457c8d0d6c1
Autor:
Lauri A. Aaltonen, Jussi Taipale, Auli Karhu, Rainer Lehtonen, Diego Arango, Torben Orntoft, Heikki Järvinen, Jukka-Pekka Mecklin, Kyösti Nuorva, Sampsa Hautaniemi, Kari Nousiainen, Juha Saharinen, Virpi Launonen, Teemu Kivioja, Heli J. Lehtonen, Iina Niittymäki, Mia Biström, Sari Tuupanen, Mikko Turunen, Heli Sammalkorpi, Mikael Björklund, Pia Alhopuro
Supplementary Figures S1-S3 and Supplementary Tables S1-S3.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9b56a8a1ee8a99e34fff4bda299fe61
https://doi.org/10.1158/1541-7786.22518903.v1
https://doi.org/10.1158/1541-7786.22518903.v1
Autor:
Lauri A. Aaltonen, Jussi Taipale, Auli Karhu, Rainer Lehtonen, Diego Arango, Torben Orntoft, Heikki Järvinen, Jukka-Pekka Mecklin, Kyösti Nuorva, Sampsa Hautaniemi, Kari Nousiainen, Juha Saharinen, Virpi Launonen, Teemu Kivioja, Heli J. Lehtonen, Iina Niittymäki, Mia Biström, Sari Tuupanen, Mikko Turunen, Heli Sammalkorpi, Mikael Björklund, Pia Alhopuro
The circadian clock regulates daily variations in physiologic processes. CLOCK acts as a regulator in the circadian apparatus controlling the expression of other clock genes, including PER1. Clock genes have been implicated in cancer-related function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d5081e44f1390e7f3dd29c5b69e3068
https://doi.org/10.1158/1541-7786.c.6542175
https://doi.org/10.1158/1541-7786.c.6542175
Publikováno v:
Hepatology International
Cell division is essential for organismal growth and tissue homeostasis. It is exceptionally significant in tissues chronically exposed to intrinsic and external damage, like the liver. After decades of studying the regulation of cell cycle by extrac
Autor:
Lingfang, Wang, Guankai, Zhan, Yasen, Maimaitiyiming, Yingfeng, Su, Shitong, Lin, Jinfeng, Liu, Kunhui, Su, Jiebo, Lin, Shizhen, Shen, Wentao, He, Fenfen, Wang, Jiafeng, Chen, Siqi, Sun, Yite, Xue, Jiaxin, Gu, Xiaojing, Chen, Jian, Zhang, Lu, Zhang, Qianqian, Wang, Kao-Jung, Chang, Shih-Hwa, Chiou, Mikael, Björklund, Hua, Naranmandura, Xiaodong, Cheng, Chih-Hung, Hsu
Publikováno v:
Cell reports. 41(4)
Human papillomavirus (HPV)-induced carcinogenesis critically depends on the viral early protein 7 (E7), making E7 an attractive therapeutic target. Here, we report that the E7 messenger RNA (mRNA)-containing oncotranscript complex can be selectively