Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Mikael Åstrand"'
Autor:
Elisabet O. Sjöström, Maxime Culot, Lisa Leickt, Mikael Åstrand, Erik Nordling, Fabien Gosselet, Christina Kaiser
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 16, Iss , Pp 100307- (2021)
The proinflammatory cytokine Interleukin-1 (IL-1), with its two isoforms α and β, has important roles in multiple pathogenic processes in the central nervous system. The present study aimed to evaluate and compare the blood-to-brain distribution of
Externí odkaz:
https://doaj.org/article/9271b6331163494a90f147b5981059de
Autor:
Johan Nilvebrant, Mikael Åstrand, Maria Georgieva-Kotseva, Mattias Björnmalm, John Löfblom, Sophia Hober
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e103094 (2014)
The epidermal growth factor receptor 2, ERBB2, is a well-validated target for cancer diagnostics and therapy. Recent studies suggest that the over-expression of this receptor in various cancers might also be exploited for antibody-based payload deliv
Externí odkaz:
https://doaj.org/article/9d349efe9e9746c9a6b9e132c5757925
Autor:
Sophia Hober, Vladimir Tolmachev, Anna Orlova, Hadis Honarvar, Mattias Sandström, Jos Buijs, Mikael Åstrand, Johan Nilvebrant, Sarah Lindbo, Javad Garousi
Analytical RP-HPLC analysis of purified DOTA-C-(HE)3-ADAPT6 ; Mass spectrum of purified DOTA-C-(HE)3-ADAPT6 ; Overlay of circular dichroism spectra from 250-195 nm for DOTA-C-(HE)3-ADAPT6 before (blue) and after (red) heating from 20-90{degree sign}C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d2c1f011fde126e002a8dad2a9a1dba
https://doi.org/10.1158/0008-5472.22406385
https://doi.org/10.1158/0008-5472.22406385
Autor:
Sophia Hober, Vladimir Tolmachev, Anna Orlova, Hadis Honarvar, Mattias Sandström, Jos Buijs, Mikael Åstrand, Johan Nilvebrant, Sarah Lindbo, Javad Garousi
Small engineered scaffold proteins have attracted attention as probes for radionuclide-based molecular imaging. One class of these imaging probes, termed ABD-Derived Affinity Proteins (ADAPT), has been created using the albumin-binding domain (ABD) o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12c118c7a1c9ffa9352b49f6017ecfc3
https://doi.org/10.1158/0008-5472.c.6507066
https://doi.org/10.1158/0008-5472.c.6507066
Autor:
Sophia Hober, Vladimir Tolmachev, Anna Orlova, Hadis Honarvar, Mattias Sandström, Jos Buijs, Mikael Åstrand, Johan Nilvebrant, Sarah Lindbo, Javad Garousi
Affinity constants of DOTA-C-(HE)3-ADAPT6 and H6-ADAPT6.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44f033af2e0728cf1d19e5313e142817
https://doi.org/10.1158/0008-5472.22406379
https://doi.org/10.1158/0008-5472.22406379
Autor:
Sophia Hober, Vladimir Tolmachev, Anna Orlova, Hadis Honarvar, Mattias Sandström, Jos Buijs, Mikael Åstrand, Johan Nilvebrant, Sarah Lindbo, Javad Garousi
Description of additional methods and procedures used in the study. Also includes Supplementary References.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23b294922eb4b21d6364af14e63245ec
https://doi.org/10.1158/0008-5472.22406382.v1
https://doi.org/10.1158/0008-5472.22406382.v1
Autor:
Christina Kaiser, Elisabet O. Sjöström, Mikael Åstrand, Maxime Culot, Fabien Gosselet, Lisa Leickt, Erik Nordling
Publikováno v:
Brain, Behavior & Immunity-Health
Brain, Behavior & Immunity-Health, Elsevier, 2021, 16, pp.100307. ⟨10.1016/j.bbih.2021.100307⟩
Brain, Behavior, & Immunity-Health, Vol 16, Iss, Pp 100307-(2021)
Brain, Behavior, & Immunity-Health
Brain, Behavior & Immunity-Health, Elsevier, 2021, 16, pp.100307. ⟨10.1016/j.bbih.2021.100307⟩
Brain, Behavior, & Immunity-Health, Vol 16, Iss, Pp 100307-(2021)
Brain, Behavior, & Immunity-Health
The proinflammatory cytokine Interleukin-1 (IL-1), with its two isoforms α and β, has important roles in multiple pathogenic processes in the central nervous system. The present study aimed to evaluate and compare the blood-to-brain distribution of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebadcd520e81982ca96fc4d25235378e
https://hal-univ-artois.archives-ouvertes.fr/hal-03472272/document
https://hal-univ-artois.archives-ouvertes.fr/hal-03472272/document
Autor:
Emma von Witting, Sarah Lindbo, Magnus Lundqvist, Marit Möller, Andreas Wisniewski, Sara Kanje, Johan Rockberg, Hanna Tegel, Mikael Åstrand, Mathias Uhlén, Sophia Hober
Publikováno v:
Molecular Pharmaceutics. 19:3451-3451
Publikováno v:
Methods in Molecular Biology ISBN: 9781071607749
Methods in Molecular Biology ISBN: 9781627039765
Methods in Molecular Biology ISBN: 9781627039765
Protein fusion tags are important tools in research when robust methods for protein purification and detection are required. In this chapter we present an efficient method for stringent protein purification. A small domain, denoted ABDz1, with affini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0f2f412c0431fb393c82a6edb0544da
https://doi.org/10.1007/978-1-0716-0775-6_13
https://doi.org/10.1007/978-1-0716-0775-6_13
Autor:
Vladimir Tolmachev, Sarah Lindbo, Sophia Hober, Anna Orlova, Hadis Honarvar, Javad Garousi, Mikael Åstrand
Publikováno v:
Bioconjugate Chemistry. 27:716-726
Engineered scaffold proteins (ESP) are high-affinity binders that can be used as probes for radionuclide imaging. Histidine-containing tags enable both efficient purification of ESP and radiolabeling with (99m)Tc(CO)3. Earlier studies demonstrated th