Zobrazeno 1 - 10
of 171
pro vyhledávání: '"Mikael, Elofsson"'
Publikováno v:
Virulence, Vol 11, Iss 1, Pp 795-804 (2020)
Pseudomonas aeruginosa is an opportunistic pathogen and a major cause of corneal infections worldwide. The bacterium secretes several toxins through its type III secretion system (T3SS) to subvert host immune responses. In addition, it is armed with
Externí odkaz:
https://doaj.org/article/648dcdc034394af08a76c27fd233b9f0
Autor:
Tobias Karlberg, Peter Hornyak, Ana Filipa Pinto, Stefina Milanova, Mahsa Ebrahimi, Mikael Lindberg, Nikolai Püllen, Axel Nordström, Elinor Löverli, Rémi Caraballo, Emily V. Wong, Katja Näreoja, Ann-Gerd Thorsell, Mikael Elofsson, Enrique M. De La Cruz, Camilla Björkegren, Herwig Schüler
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
The cellular toxicity of Pseudomonas exotoxin-S and -T depends on their activation by 14-3-3 but the underlying molecular mechanism is not fully understood. Here, the authors show that a previously unrecognized 14-3-3:exotoxin binding interface is su
Externí odkaz:
https://doaj.org/article/744bcb86311e401b9b088850c4b2acfd
Autor:
Emil Johansson, Rémi Caraballo, Daniel L. Hurdiss, Nitesh Mistry, C. David Andersson, Rebecca F. Thompson, Neil A. Ranson, Georg Zocher, Thilo Stehle, Niklas Arnberg, Mikael Elofsson
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 16, p 8418 (2021)
Coxsackievirus A24 variant (CVA24v) is the primary causative agent of the highly contagious eye infection designated acute hemorrhagic conjunctivitis (AHC). It is solely responsible for two pandemics and several recurring outbreaks of the disease ove
Externí odkaz:
https://doaj.org/article/a8564642779c45aa8d6d135739354bcc
Autor:
Naresh Sunduru, Mona Svensson, Mariateresa Cipriano, Sania Marwaha, C. David Andersson, Richard Svensson, Christopher J. Fowler, Mikael Elofsson
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 32, Iss 1, Pp 513-521 (2017)
Fatty acid amide hydrolase (FAAH) is a promising target for the development of drugs to treat neurological diseases. In search of new FAAH inhibitors, we identified 2-(4-cyclohexylphenoxy)-N-(3-(oxazolo[4,5-b]pyridin-2-yl)phenyl)acetamide, 4g, with a
Externí odkaz:
https://doaj.org/article/56045177574f429a8dafbbdc15fb8d71
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 9 (2019)
Antibiotics are becoming less effective in treatment of infections caused by multidrug-resistant Pseudomonas aeruginosa. Antimicrobial therapies based on the inhibition of specific virulence-related traits, as opposed to growth inhibitors, constitute
Externí odkaz:
https://doaj.org/article/c1a13415e9ca4d3e8a5d26ec713c244f
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
In this study, we describe the application of a transformed Chlamydia trachomatis strain constitutively expressing the red fluorescent protein mCherry, to allow real-time monitoring of the infection cycle and screening for agents that block replicati
Externí odkaz:
https://doaj.org/article/5f44da02ae6c425bad1b642d38147662
Autor:
Zahra El-Schich, Yuecheng Zhang, Tommy Göransson, Nishtman Dizeyi, Jenny L. Persson, Emil Johansson, Remi Caraballo, Mikael Elofsson, Sudhirkumar Shinde, Börje Sellergren, Anette Gjörloff Wingren
Publikováno v:
Applied Sciences, Vol 11, Iss 7, p 3256 (2021)
Sialylations are post-translational modifications of proteins and lipids that play important roles in many cellular events, including cell-cell interactions, proliferation, and migration. Tumor cells express high levels of sialic acid (SA), which are
Externí odkaz:
https://doaj.org/article/ea0cee73aa8042e9afa7c88f73c35cf4
Publikováno v:
Biomolecules, Vol 11, Iss 1, p 55 (2021)
Pseudomonas aeruginosa is an opportunistic bacterial pathogen that employs its type III secretion system (T3SS) during the acute phase of infection to translocate cytotoxins into the host cell cytoplasm to evade the immune system. The PcrV protein is
Externí odkaz:
https://doaj.org/article/d7c9736cc12441e79098053d35072517
Autor:
Emil Johansson, Rémi Caraballo, Georg Zocher, Nitesh Mistry, Niklas Arnberg, Thilo Stehle, Mikael Elofsson
Publikováno v:
RSC Advances. 12:2319-2331
Coxsackievirus A24 variant (CVA24v) is responsible for several outbreaks and two pandemics of the highly contagious eye infection acute hemorrhagic conjunctivitis (AHC). Currently, neither prevention (vaccines) nor treatments (antivirals) are availab
Autor:
Yong-Dae Gwon, Mårten Strand, Richard Lindqvist, Emma Nilsson, Michael Saleeb, Mikael Elofsson, Anna K. Överby, Magnus Evander
Publikováno v:
Viruses, Vol 12, Iss 3, p 351 (2020)
Most flaviviruses are arthropod-borne viruses, transmitted by either ticks or mosquitoes, and cause morbidity and mortality worldwide. They are endemic in many countries and have recently emerged in new regions, such as the Zika virus (ZIKV) in South
Externí odkaz:
https://doaj.org/article/1e676e5a9f884d1d808fc566965047a7