Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Mika Vesanen"'
Autor:
Mika Vesanen, Ben Berkhout, Min Lu, Aditi Master, Paul J. Maddon, Rogier W. Sanders, Linnea Schiffner, Roopa Kalyanaraman, John P. Moore, Norbert Schuelke, Maciej Paluch, William C. Olson
Publikováno v:
Journal of Virology. 76:8875-8889
The envelope glycoprotein (Env) complex of human immunodeficiency virus type 1 has evolved a structure that is minimally immunogenic while retaining its natural function of receptor-mediated virus-cell fusion. The Env complex is trimeric; its six ind
Autor:
Ping Zhu, Paul W. H. I. Parren, Paul J. Maddon, Norbert Schülke, Anthony R. Villa, James M. Binley, Deborah J. Anselma, Kenneth H. Roux, Mika Vesanen, Rogier W. Sanders, John P. Moore, Min Lu, William C. Olson
Publikováno v:
Journal of virology, 76(15), 7760-7776. American Society for Microbiology
The native, fusion-competent form of the human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein complex is a trimeric structure composed of three gp120 subunits and three gp41 subunits; the receptor-binding (CD4 and coreceptor) sites are l
Autor:
Agegnehu Gettie, James M. Binley, Jenny Booth, Lynette S. W. Sawyer, Mark G. Lewis, David C. Montefiori, Brian Clas, Sebastian Bonhoeffer, John P. Moore, Preston A. Marx, Mika Vesanen
Publikováno v:
Virology. 270(1):237-249
Antibody responses are often considered to play only a limited role in controlling viremia during chronic infections with human or simian immunodeficiency virus (SIV). We investigated this by determining the effect of passively infused antibody on pl
Autor:
Sebastian Bonhoeffer, Xia Jin, Richard A. Koup, Daniel C. Douek, David D. Ho, Yunzhen Cao, Peter J. Kuebler, Douglas F. Nixon, Mika Vesanen, Martin Markowitz
Publikováno v:
Immunology Letters. 66:219-228
The mechanisms that lead to maintenance of an active effector cytotoxic T-cell (CTL) response in Human Immunodeficiency Virus type-1 (HIV-1) infection are not well understood. We have investigated the role of antigen in maintenance of an HIV-1 specif
Autor:
Arlene Hurley, Kalle Saksela, Martin Markowitz, Paulina Essunger, Mika Vesanen, David D. Ho, Yunzhen Cao, Alan S. Perelson
Publikováno v:
Nature. 387:188-191
Analysis of changes in viral load after initiation of treatment with potent antiretroviral agents has provided substantial insight into the dynamics of human immunodeficiency virus type 1 (HIV-1). The concentration of HIV-1 in plasma drops by approxi
Publikováno v:
Journal of General Virology. 75:201-206
We have studied human immunodeficiency virus type 1 (HIV-1) infection in human SH-SY5Y neuroblastoma cells at various stages of morphological differentiation. Two days' treatment of the cells with retinoic acid (RA) or dibutyryl cAMP (db-cAMP) result
Publikováno v:
Journal of General Virology. 73:1753-1760
Human immunodeficiency virus type 1 (HIV-1) infection was studied in two different human neuroblastoma cell lines, SK-N-MC and SH-SY5Y. Results from immunofluorescence analysis indicate that SK-N-MC cells express a 68K neurofilament, and SH-SY5Y cell
Autor:
Yunzhen Cao, Simon Monard, Andrew H. Talal, Fang Fang, Judy Johnson, Mika Vesanen, Arlene Hurley, Rhonda G. Kost, Zhaoyao Zheng, Martin Markowitz, Lynn Smiley
Publikováno v:
Journal of acquired immune deficiency syndromes (1999). 26(1)
Objectives: We evaluated virologic and immunologic responses to antiretroviral therapy in gut-associated lymphoid tissue (GALT) compared with those found in peripheral blood. Methods: Eight HIV-1-infected individuals were treated with three reverse t
Autor:
Sharon R Lewin, Linqi Zhang, M. Markowitz, M. Duran, David D. Ho, Leondios G. Kostrikis, Mika Vesanen, Arlene Hurley
Publikováno v:
Europe PubMed Central
We have designed a novel, precise, and sensitive assay to measure unspliced (US) human immunodeficiency virus type 1 (HIV-1) mRNA in peripheral blood mononuclear cells of HIV-1-infected individuals by using real-time PCR and molecular beacons. Indivi
Autor:
Linqi Zhang, Bharat Ramratnam, Klara Tenner-Racz, Yuxian He, Mika Vesanen, Sharon Lewin, Andrew Talal, Paul Racz, Alan S. Perelson, Bette T. Korber, Martin Markowitz, Yong Guo, Margarita Duran, Arlene Hurley, John Tsay, Yu-Ching Huang, Chia-Ching Wang, David D. Ho
Publikováno v:
The New England journal of medicine. 340(21)
In patients infected with human immunodeficiency virus type 1 (HIV-1), combination antiretroviral therapy can result in sustained suppression of plasma levels of the virus. However, replication-competent virus can still be recovered from latently inf