Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Mika Reznik"'
Publikováno v:
Journal of Cell Science. 118:1151-1159
During pre-mRNA splicing, introns are removed and exons are ligated to form an mRNA. Exon choice is determined by different nuclear protein concentrations varying among tissues and cell types or by developmental stage. These can be altered by differe
Publikováno v:
Molecular biology of the cell. 15(8)
Precursor-mRNA splicing removes the introns and ligates the exons to form a mature mRNA. This process is carried out in a spliceosomal complex containing >150 proteins and five small nuclear ribonucleoproteins. Splicing protein hSlu7 is required for
Autor:
Rotem, Sorek, Galit, Lev-Maor, Mika, Reznik, Tal, Dagan, Frida, Belinky, Dan, Graur, Gil, Ast
Publikováno v:
Molecular cell. 14(2)
Alu exonization, which is an evolutionary pathway that creates primate-specific transcriptomic diversity, is a powerful tool for studying alternative-splicing regulation. Through bioinformatic analyses combined with experimental methodology, we ident
Autor:
Noam Shomron, Neta Pessah, Hong Xin, Gil Ast, Katherine S. Bowdish, Doron Shabat, Mika Reznik, Ferda Yantiri, Marina Shamis
Publikováno v:
Bioorganicmedicinal chemistry. 12(8)
Two new prodrugs of CPT were synthesized, based on carbamate linkages between the 20-hydroxy group of CPT and a linker designed to be enzymatically removed by either Penicillin-G-Amidase or catalytic antibody 38C2. Cell growth inhibition assays showe