Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Mika Okamoto"'
Autor:
Taiki Homma, Mika Okamoto, Ryohto Koharazawa, Mayu Hayakawa, Taiki Fushimi, Chisato Tode, Yoshihisa Hirota, Naomi Osakabe, Masanori Baba, Yoshitomo Suhara
Publikováno v:
ACS Omega, Vol 8, Iss 45, Pp 42248-42263 (2023)
Externí odkaz:
https://doaj.org/article/9294761cbcc441b588491fe400e0ad49
Autor:
Takashi Kajiya, Hayate Sawayama, Eriko Arima, Mika Okamoto, Masanori Baba, Masaaki Toyama, Kosuke Okuya, Makoto Ozawa, Nobuhiko Atsuchi, Junichiro Nishi, Yasuo Suda
Publikováno v:
Viruses, Vol 14, Iss 11, p 2577 (2022)
Background: The transmissible capacity and toxicity of SARS-CoV-2 variants are continually changing. We report here the follow-up study of hospitalized COVID-19 patients from 2020 to 2022. It is known that the PCR diagnosis for hospitalized patients
Externí odkaz:
https://doaj.org/article/e6b216161c2a46d082245b6fdab8b75e
Autor:
Masaaki Toyama, Koichi Watashi, Masanori Ikeda, Atsuya Yamashita, Mika Okamoto, Kohji Moriishi, Masamichi Muramatsu, Takaji Wakita, Ashoke Sharon, Masanori Baba
Publikováno v:
Antimicrob Agents Chemother
Novel neplanocin A derivatives have been identified as potent and selective inhibitors of hepatitis B virus (HBV) replication in vitro. These include (1S,2R,5R)-5-(5-bromo-4-methyl-7H-pyrrolo[2,3-d]-pyrimidin-7-yl)-3-(hydroxymethyl)cyclopent-3-ene-1,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aad6b5146b8c115729ed3b00f4c86340
https://europepmc.org/articles/PMC9211404/
https://europepmc.org/articles/PMC9211404/
Autor:
Mika Okamoto, Taiji Unoki, Yoshitaka Furukawa, Teruto Hashiguchi, Heiichiro Hamada, Kazuto Kamikawaji, Yukie Tashiro, Hiromasa Inoue, Masanori Baba
Publikováno v:
Journal of Infection and Chemotherapy. 26:279-281
We report an AIDS patient with a high HIV RNA copy number in the plasma who was successfully treated for prolonged Mycobacterium avium bacteremia and other complications. An HIV-infected patient with high fever, anemia, high alkaline phosphatase, cys
Publikováno v:
Virus Research. 260:86-93
Galectin-3 (Gal-3) is involved in many biological processes and pathogenesis of diseases in part through nuclear factor (NF)-κB activation. We demonstrated that Gal-3 expression was significantly induced by tumor necrosis factor (TNF)-α or phorbol
Publikováno v:
Biochemical and biophysical research communications. 530(3)
The current antiretroviral therapy cannot cure the patients infected with human immunodeficiency virus type 1 (HIV-1) due to the existence of latently infected cells capable of virus production from harboring proviral DNA. MazF is an ACA nucleotide s
Autor:
Masaaki Toyama, Makoto Yoshimitsu, Kenji Ishitsuka, Ikuko Watanabe, Satoshi Kishimoto, Riri Yokota, Yuji Ito, Shun Hashimoto, Masanori Baba, Mika Okamoto
Publikováno v:
Anticancer research. 40(8)
Background/aim Adult T-cell leukemia (ATL) is a hematological malignancy caused by infection with human T-cell leukemia virus type 1 (HTLV-1). Chemotherapy, antibody therapy, and bone marrow transplantation are used to treat this disease, however, me
Autor:
Masaaki Toyama, Takaji Wakita, Masanori Baba, Norikazu Sakakibara, Masashi Mizokami, Koichi Watashi, Mika Okamoto, Masaya Sugiyama, Masanori Ikeda, Midori Takeda
Publikováno v:
Virus research. 271
Chronic hepatitis B virus (HBV) infection is currently treated with nucleoside/nucleotides analogs. They are potent inhibitors of HBV DNA polymerase, which also functions as reverse transcriptase. Although nucleoside/nucleotide analogs efficiently su
Autor:
Naoki Mitsuhiro, Olufunmilayo G. Oyero, Masanori Baba, Mika Okamoto, Masaaki Toyama, Akemi Hidaka, A.A. Onifade
Publikováno v:
African Journal of Traditional, Complementary, and Alternative Medicines
African Journal of Traditional, Complementary and Alternative Medicines; Vol 13, No 6 (2016); 144-148
African Journal of Traditional, Complementary and Alternative Medicines; Vol 13, No 6 (2016); 144-148
Background: Hepatitis C virus (HCV) infection became curable because of the development of direct acting antivirals (DAAs). However, the high cost of DAAs has greatly impeded their potential impact on the treatment of HCV infection. As a result, hepa
Isolation and characterization of hepatitis C virus resistant to a novel phenanthridinone derivative
Autor:
Wataru Ito, Mika Okamoto, Koichi Watashi, Masanori Ikeda, Takaji Wakita, Yuichi Hashimoto, Masanori Baba, Masaaki Toyama
Publikováno v:
Antiviral Chemistry and Chemotherapy. 24:148-154
Background The novel phenanthridinone derivative HA-719 has recently been identified as a highly potent and selective inhibitor of hepatitis C virus replication. To elucidate its mechanism of inhibition, we have isolated and analyzed a clone of hepat