Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Mika Munari"'
Publikováno v:
eLife, Vol 7 (2018)
Externí odkaz:
https://doaj.org/article/98b27b2cbb9446f3ad8c7917ef2cc95e
Publikováno v:
eLife, Vol 7 (2018)
Conformational dynamics underlie enzyme function, yet are generally inaccessible via traditional structural approaches. FRET has the potential to measure conformational dynamics in vitro and in intact cells, but technical barriers have thus far limit
Externí odkaz:
https://doaj.org/article/bfcbb8ec25cc4864913c6b989584adb9
Autor:
Alex J. Eddins, E. James Petersson, Tiberiu S. Mihaila, Mika Munari, Sharona E. Gordon, D. Miklos Robkis, William N. Zagotta, Yarra Venkatesh, Robert J. Blizzard, Chloe M. Jones, Ryan A. Mehl
Publikováno v:
Chemical Science
Acridonylalanine (Acd) is a fluorescent amino acid that is highly photostable, with a high quantum yield and long fluorescence lifetime in water. These properties make it superior to existing genetically encodable fluorescent amino acids for monitori
Publikováno v:
The Journal of General Physiology
Transition metal ion FRET between a noncanonical fluorescent amino acid incorporated into TRPV1 and metal ions bound to the cell plasma can be used to measure distances and dynamics between cytosolic domains of proteins and the membrane.
Despite
Despite
Publikováno v:
eLife, Vol 7 (2018)
Publikováno v:
eLife, Vol 7 (2018)
eLife
eLife
Conformational dynamics underlie enzyme function, yet are generally inaccessible via traditional structural approaches. FRET has the potential to measure conformational dynamicsin vitroand in intact cells, but technical barriers have thus far limited
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36e5566442366849cf016e1b7a29e0e3
Autor:
Tamara Rosenbaum, Ariela Gordon-Shaag, Mika Munari, Jeremy Cooper, Sharona E. Gordon, León D. Islas
Publikováno v:
The Journal of General Physiology
Cyclic nucleotide–gated (CNG) ion channels are nonselective cation channels with a high permeability for Ca2+. Not surprisingly, they are blocked by a number of Ca2+ channel blockers including tetracaine, pimozide, and diltiazem. We studied the eff
Publikováno v:
The Journal of General Physiology
TRPV1 ion channels mediate the response to painful heat, extracellular acidosis, and capsaicin, the pungent extract from plants in the Capsicum family (hot chili peppers) (Szallasi, A., and P.M. Blumberg. 1999. Pharmacol. Rev. 51:159–212; Caterina,
Autor:
Héctor Jiménez Salazar, Andres Jara-Oseguera, Mika Munari, Sharona E. Gordon, Itzel Llorente, Refugio García-Villegas, León D. Islas, Tamara Rosenbaum
Some members of the transient receptor potential (TRP) family of cation channels mediate sensory responses to irritant substances. Although it is well known that TRPA1 channels are activated by pungent compounds found in garlic, onion, mustard and ci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca8036289ff710b10cadc86fa4ab44b0
https://europepmc.org/articles/PMC4370189/
https://europepmc.org/articles/PMC4370189/