Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Mika Kitsukawa"'
Autor:
Masashi Uchida, Mitsuko Miyamoto, Mika Kitsukawa, Masafumi Isogaya, Ryoji Hayashi, Kuniaki Kawamura, Takeshi Ishigaki, Yasuhiro Morita, Katsuhiko Iseki
Publikováno v:
Molecules, Vol 17, Iss 2, Pp 1233-1246 (2012)
An efficient synthesis of a highly potent and selective IP (PGI2 receptor) agonist that is not structurally analogous to PGI2 is described. This synthesis is accomplished through the following key steps: Nucleophilic ring-opening of 3-(4-chlorophenyl
Externí odkaz:
https://doaj.org/article/cba6f75255bc410fb2073936b36728ea
Autor:
Yoshiji Asaoka, Hiromi Tsuchiyama, Mayumi Nakajima, Mayu Mutsuga, Tomoya Miyoshi, Akihisa Maeda, Keiyu Oshida, Kei Takahashi, Mika Kitsukawa, Yohei Miyamoto
Publikováno v:
Toxicology Letters. 280:133-141
The murine local lymph node assay (LLNA) is widely used to test chemicals to induce skin sensitization. Exposure of mouse auricle skin to a sensitizer results in proliferation of local lymph node T cells, which has been measured by in vivo incorporat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b38006cfe2c7995bb8c65f0b9ed0d14f
https://doi.org/10.1016/j.toxlet.2017.08.009
https://doi.org/10.1016/j.toxlet.2017.08.009
Autor:
Mika Kitsukawa1, Hiromi Tsuchiyama1, Akihisa Maeda1, Keiyu Oshida1, Yohei Miyamoto1 Youhei_Miyamoto@nts.toray.co.jp
Publikováno v:
Journal of Toxicological Sciences. Aug2014, Vol. 39 Issue 4, p545-550. 6p.
Autor:
Yohei Miyamoto, Tomoya Miyoshi, Keiyu Oshida, Sachiko Suga, Akihisa Maeda, Shunsuke Iwano, Mika Kitsukawa
Publikováno v:
Toxicology Letters. 205:79-85
The murine local lymph node assay (LLNA) is an immunologically based test of the sensitizing potential of immunotoxicants, but also evaluates immunosuppressive potential with good sensitivity and specificity. We conducted the LLNA with calcineurin in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::449b0db7876b4ddf8b0ce8cf0e402bc7
https://doi.org/10.1016/j.toxlet.2011.05.1017
https://doi.org/10.1016/j.toxlet.2011.05.1017
Autor:
Mika Kitsukawa, Yasushi Ohizumi, Katsuhiko Muraki, Susumu Ohya, Daiju Yamazaki, Shin-ya Saito, Yuji Imaizumi, Hidekazu Kiyoshi
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 291:H2723-H2734
Changes in K+ conductances and their contribution to membrane depolarization in the setting of an acidic pH environment have been studied in myocytes from aortic smooth muscle cells of spontaneously hypertensive rats (SHR) compared with those from Wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b15019966ec06a955490e2b5a375e69
https://doi.org/10.1152/ajpheart.00894.2005
https://doi.org/10.1152/ajpheart.00894.2005
Publikováno v:
The Journal of toxicological sciences. 39(4)
2-Cyano-3, 12-dioxooleana-1, 9-dien-28-oic acid methyl ester (CDDO-Me; bardoxolone methyl) is one of the synthetic oleanane triterpenoids (SOs). It is known that it is the strongest Nrf2/ARE signaling inducer of SOs and slightly inhibits immune respo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04cb645f46e0dbcc4e9215c955fdbf04
https://pubmed.ncbi.nlm.nih.gov/25056779
https://pubmed.ncbi.nlm.nih.gov/25056779
Autor:
Shunichi Kimura, Mika Kitsukawa, Katsuhiko Muraki, Minoru Watanabe, Yuji Imaizumi, Susumu Ohya
Publikováno v:
Japanese journal of pharmacology. 84(1)
The single channel current of intermediate conductance Ca2 +-activated K+ channel (IK channel) was measured in mouse urinary bladder myocytes (MBM), and the molecular basis of the channel was suggested to be the SK4 subtype by RT-PCR. Among Ca2+-acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06cafa0c66462661a54eccfd4340dec9
https://pubmed.ncbi.nlm.nih.gov/11043463
https://pubmed.ncbi.nlm.nih.gov/11043463