Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Mika Kanuka"'
Autor:
Taizo Kawano, Mitsuaki Kashiwagi, Mika Kanuka, Chung-Kuan Chen, Shinnosuke Yasugaki, Sena Hatori, Shinichi Miyazaki, Kaeko Tanaka, Hidetoshi Fujita, Toshiro Nakajima, Masashi Yanagisawa, Yoshimi Nakagawa, Yu Hayashi
Publikováno v:
Cell Reports, Vol 42, Iss 3, Pp 112267- (2023)
Summary: Sleep is regulated by peripheral tissues under fatigue. The molecular pathways in peripheral cells that trigger systemic sleep-related signals, however, are unclear. Here, a forward genetic screen in C. elegans identifies 3 genes that strong
Externí odkaz:
https://doaj.org/article/97bf92a024cc488094eff41a043f31c1
Autor:
Mitsuaki Kashiwagi, Mika Kanuka, Kaeko Tanaka, Masayo Fujita, Ayaka Nakai, Chika Tatsuzawa, Kazuto Kobayashi, Kazutaka Ikeda, Yu Hayashi
Publikováno v:
Molecular Brain, Vol 14, Iss 1, Pp 1-4 (2021)
Abstract Despite the established roles of the dopaminergic system in promoting arousal, the effects of loss of dopamine on the patterns of sleep and wakefulness remain elusive. Here, we examined the sleep architecture of dopamine-deficient (DD) mice,
Externí odkaz:
https://doaj.org/article/f185785df9594fc2a899c8013e7919f3
Autor:
Shinnosuke Yasugaki, Chih-Yao Liu, Mitsuaki Kashiwagi, Mika Kanuka, Takato Honda, Shingo Miyata, Masashi Yanagisawa, Yu Hayashi
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
Repeated stress is a risk factor for mental disorders and can also lead to sleep disturbances. Although the effects of stress on sleep architecture have been investigated in rodents, the length of the stress exposure period in most studies has been l
Externí odkaz:
https://doaj.org/article/e58132abf55c432d885a3c2f6964a2c8
Autor:
Yasuhiro Ogawa, Yoko Irukayama-Tomobe, Nobuyuki Murakoshi, Maiko Kiyama, Yui Ishikawa, Naoto Hosokawa, Hiromu Tominaga, Shuntaro Uchida, Saki Kimura, Mika Kanuka, Miho Morita, Michito Hamada, Satoru Takahashi, Yu Hayashi, Masashi Yanagisawa
Publikováno v:
eLife, Vol 5 (2016)
Sepsis is a systemic inflammatory response to infection, accounting for the most common cause of death in intensive care units. Here, we report that peripheral administration of the hypothalamic neuropeptide orexin improves the survival of mice with
Externí odkaz:
https://doaj.org/article/b97c3e7543c743b6abdc7a2ccd886b22
Autor:
Ayaka Nakai, Mitsuaki Kashiwagi, Seiya Mizuno, Hiromasa Funato, Fumihiro Sugiyama, Miyo Kakizaki, Takeshi Sakurai, Masashi Yanagisawa, Taizo Kawano, Yu Hayashi, Mika Kanuka, Chika Tatsuzawa, Aya Ikkyu, Nanae Nagata, Satoru Takahashi, Marina Takagi, Kaeko Tanaka, Tomoyuki Fujiyama
Publikováno v:
Genetics
The molecular mechanism regulating sleep largely remains to be elucidated. In humans, families that carry mutations in TFAP2B, which encodes the transcription factor AP-2β, self-reported sleep abnormalities such as short-sleep and parasomnia. Notabl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d77845bc668d31eb27cf3a5bcbc9954
https://pubmed.ncbi.nlm.nih.gov/32878901
https://pubmed.ncbi.nlm.nih.gov/32878901
Autor:
Masashi Yanagisawa, Mika Kanuka, Chika Tatsuzawa, Harukazu Suzuki, Yu Hayashi, Miho Morita, Jay W. Shin, Hitomi Suzuki, Shigeyoshi Itohara, Mitsuaki Kashiwagi, Kaeko Tanaka, Taizo Kawano
Publikováno v:
Current biology : CB. 30(6)
Summary Classical transection studies suggest that, in addition to the hypothalamus, the brainstem is essential for non-rapid eye movement (NREM) sleep. The circuits underlying this function, however, have remained largely unknown. We identified a ci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6660dfb4ef282a57ca648ce6ed2b2a60
https://pubmed.ncbi.nlm.nih.gov/32032507
https://pubmed.ncbi.nlm.nih.gov/32032507
Autor:
Takaomi C. Saido, Taizo Kawano, Pimpimon Nondhalee, Mitsuaki Kashiwagi, Yu Hayashi, Miho Morita, Mika Kanuka, Chika Tatsuzawa, Sakura Eri B. Maezono, Takashi Saito, Masanori Sakaguchi
Publikováno v:
eneuro. 7:ENEURO.0093-20.2020
Alzheimer’s disease (AD) patients often suffer from sleep disturbances. Alterations in sleep, especially rapid eye movement sleep (REMS), can precede the onset of dementia. To accurately characterize the sleep impairments accompanying AD and their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4dfa983cc8770188db39bea76875e1e3
https://doi.org/10.1523/eneuro.0093-20.2020
https://doi.org/10.1523/eneuro.0093-20.2020
Autor:
Hiromu Tominaga, S. Kimura, Naoto Hosokawa, Miho Morita, Nobuyuki Murakoshi, Maiko Kiyama, Yoko Irukayama-Tomobe, Yu Hayashi, Michito Hamada, Satoru Takahashi, Yui Ishikawa, Shuntaro Uchida, Masashi Yanagisawa, Yasuhiro Ogawa, Mika Kanuka
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f6538d7a25901c4e6ccfecb25ebf6b3
https://doi.org/10.7554/elife.21055.018
https://doi.org/10.7554/elife.21055.018
Autor:
Maiko Kiyama, Naoto Hosokawa, Satoru Takahashi, Yui Ishikawa, Nobuyuki Murakoshi, Yu Hayashi, Yoko Irukayama-Tomobe, Michito Hamada, Hiromu Tominaga, Yasuhiro Ogawa, Mika Kanuka, Miho Morita, Shuntaro Uchida, Masashi Yanagisawa, S. Kimura
Publikováno v:
eLife
eLife, Vol 5 (2016)
eLife, Vol 5 (2016)
Sepsis is a systemic inflammatory response to infection, accounting for the most common cause of death in intensive care units. Here, we report that peripheral administration of the hypothalamic neuropeptide orexin improves the survival of mice with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6062ea0262ba5cf098e6dd28a5ea9b68
http://europepmc.org/articles/PMC5245965
http://europepmc.org/articles/PMC5245965
Autor:
Reiko Ando, Kosuke Yasuda, Mitsuaki Kashiwagi, Mika Kanuka, Yu Hayashi, Shigeyoshi Itohara, Kazuya Sakai
Publikováno v:
Science (New York, N.Y.). 350(6263)
Neurons that regulate sleep stages Just what sleep is for remains a bit of a mystery. During sleep, we switch several times between so-called rapid eye movement (REM) and non-REM sleep. Hayashi et al. used sophisticated developmental cell fate mappin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17ea644f8f2cf4443a2be4d6c1b49a85
https://pubmed.ncbi.nlm.nih.gov/26586746
https://pubmed.ncbi.nlm.nih.gov/26586746