Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Mika Hirashima"'
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. 96:3-B
Autor:
Yoshinari Takasaki, Shigeto Kobayashi, Shinji Morimoto, Hiroshi Hashimoto, Kazuhiko Kaneda, Naoto Tamura, Mika Hirashima, Ran Matsudaira, Masuyuki Nawata, Makoto Ikeda, Michiko Tajima
Publikováno v:
Internal Medicine. 46:409-414
Conventional therapy for Wegener's granulomatosis, steroid and cyclophosphamide, fails to control disease activity in some refractory patients and has treatment-related toxicity. B cell depletion therapy using rituximab, a chimeric anti-CD20 monoclon
Autor:
Kim Young-Joon, Kazuhiko Kaneda, Kaori Abe, Hiroshi Tsuda, Toru Fukazawa, Shuuhei Takai, Yoko Tabushi, Hiroshi Hashimoto, Mika Hirashima
Publikováno v:
Modern rheumatology. 13(2)
A case of aplastic anemia with a 16-year history of systemic lupus erythematosus (SLE) is described. The diagnosis of aplastic anemia was established by bone marrow biopsy. Aplastic anemia is an extremely rare complication of SLE. The pathogenesis of
Autor:
Hiroshi Hashimoto, Toru Fukazawa, Junichi Asakawa, Makoto Ogaki, Chifuyu Ushiyama, Yoshinari Takasaki, Man Ami Seki, Mika Hirashima, Kaori Abe
Publikováno v:
Journal of Clinical Immunology. 19:58-66
CD80 and CD86 were detected in high amounts on circulating T cells in the peripheral blood of some patients with systemic lupus erythematosus (SLE), using flow cytometry and monoclonal antibodies. Patients with other connective tissue diseases did no
Autor:
Toru Fukazawa, Chiharu Yamaji, Yuko Morita, Shuuhei Takai, Makio Kusaoi, Hiroshi Hashimoto, Yoshinari Takasaki, Mika Hirashima
Publikováno v:
Modern Rheumatology. 13:87-89
We report a case of systemic sclerosis (SSc) associated with inclusion body myositis (IBM). A 58-year-old man was diagnosed as having SSc at the age of 35 years, and had been suffering from chronic progressive weakness and atrophy of the limb muscles
Autor:
S. Touyama, Mika Hirashima, Toru Fukazawa, Y. Morita, T. Morita, Yoshinari Takasaki, K. Kaga, K. Morita, Hiroshi Hashimoto, Makio Kusaoi
Publikováno v:
Scandinavian journal of rheumatology. 35(4)
To investigate the effect of methotrexate (MTX) on cytokine production by activated CD4+ T-cells in patients with rheumatoid arthritis (RA).The effect of MTX on intracellular expression of interferon-gamma (IFN-gamma) and interleukin-4 (IL-4), and ce
Publikováno v:
Lupus. 13(1)
The objective of this study was to determine the expression and activity of CTLA4 in T-cells of systemic lupus erythematosus (SLE) patients. Expression of CTLA4 on freshly isolated peripheral blood T-cells was evaluated in 33 SLE patients and 25 cont
Autor:
Takeshi Miyano, M Oonishi, Shinichi Niijima, Y. Yamashiro, Toru Fukazawa, Yoshinari Takasaki, Hiroshi Hashimoto, A Murashima, Atsuyuki Yamataka, Mika Hirashima
Publikováno v:
Annals of the rheumatic diseases. 63(1)
To determine the long term prognosis of children of patients with systemic lupus erythematosus (SLE).Children of patients with SLE were invited to attend our clinic for physical examination and laboratory tests. A total of 195 children (aged 4 months