Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Mikaël Bédard"'
Autor:
Emmanuelle Wilhelm, Mikaël Poirier, Morgane Da Rocha, Mikaël Bédard, Patrick P McDonald, Pierre Lavigne, Christie L Hunter, Brendan Bell
Publikováno v:
PLoS Pathogens, Vol 20, Iss 5, p e1011821 (2024)
The human immunodeficiency virus (HIV) integrates into the host genome forming latent cellular reservoirs that are an obstacle for cure or remission strategies. Viral transcription is the first step in the control of latency and depends upon the hija
Externí odkaz:
https://doaj.org/article/acce5adfc29f4b478bfd2184a855265c
Autor:
Ariane Thérien, Mikaël Bédard, Damien Carignan, Gervais Rioux, Louis Gauthier-Landry, Marie-Ève Laliberté-Gagné, Marilène Bolduc, Pierre Savard, Denis Leclerc
Publikováno v:
Journal of Nanobiotechnology, Vol 15, Iss 1, Pp 1-13 (2017)
Abstract Background Flexuous rod-shaped nanoparticles made of the coat protein (CP) of papaya mosaic virus (PapMV) have been shown to trigger innate immunity through engagement of toll-like receptor 7 (TLR7). PapMV nanoparticles can also serve as a v
Externí odkaz:
https://doaj.org/article/8665194a58ac4877adf58fa58902b9d0
Autor:
Loïka Maltais, Martin Montagne, Mikaël Bédard, Cynthia Tremblay, Laura Soucek, Pierre Lavigne
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0174413 (2017)
It is classically recognized that the physiological and oncogenic functions of Myc proteins depend on specific DNA binding enabled by the dimerization of its C-terminal basic-region-Helix-Loop-Helix-Leucine Zipper (b-HLH-LZ) domain with that of Max.
Externí odkaz:
https://doaj.org/article/47ee33916a1247eab6532ff7bd65aafa
Publikováno v:
Biochemistry. 56:5099-5111
Caspases are cysteinyl peptidases involved in inflammation and apoptosis during which hundreds of proteins are cleaved by executioner caspase-3 and -7. Despite the fact that caspase-3 has a higher catalytic activity, caspase-7 is more proficient at c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d69f886d28a24e802595b184092f63fd
https://doi.org/10.1021/acs.biochem.7b00298
https://doi.org/10.1021/acs.biochem.7b00298
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 85:199-206
c-Myc is a basic helix-loop-helix leucine zipper (b-HLH-LZ) transcription factor deregulated in the majority of human cancers. As a heterodimer with Max, another b-HLH-LZ transcription factor, deregulated and persistent c-Myc accumulates at transcrip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f66d669e05ea640c258468f5fc459410
https://doi.org/10.1002/prot.25214
https://doi.org/10.1002/prot.25214
Autor:
Jean-Baptiste Duvignaud, Shigeyuki Yokoyama, Takashi Nagata, Yutaka Muto, Michel Vincent, Mikaël Bédard, Stéphane M. Gagné
Publikováno v:
Biochemistry. 55:2553-2566
p54(nrb)/NonO is a nuclear RNA-binding protein involved in many cellular events such as pre-mRNA processing, transcription, and nuclear retention of hyper-edited RNAs. In particular, it participates in the splicing process by directly binding the 5'
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9763f55d24edeea3501cb62b13b41cf
https://doi.org/10.1021/acs.biochem.5b01240
https://doi.org/10.1021/acs.biochem.5b01240
Autor:
Pierre Savard, Marilène Bolduc, Louis Gauthier-Landry, Ariane Thérien, Marie-Eve Laliberté-Gagné, Gervais Rioux, Denis Leclerc, Mikaël Bédard, Damien Carignan
Publikováno v:
Journal of Nanobiotechnology, Vol 15, Iss 1, Pp 1-13 (2017)
Journal of Nanobiotechnology
Journal of Nanobiotechnology
Background Flexuous rod-shaped nanoparticles made of the coat protein (CP) of papaya mosaic virus (PapMV) have been shown to trigger innate immunity through engagement of toll-like receptor 7 (TLR7). PapMV nanoparticles can also serve as a vaccine pl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::758cc86e28425eec5e8c46b8bae65a3c
https://doi.org/10.1186/s12951-017-0289-y
https://doi.org/10.1186/s12951-017-0289-y
Autor:
Thérien, Ariane, Mikaël Bédard, Carignan, Damien, Rioux, Gervais, Gauthier-Landry, Louis, Marie-Ève Laliberté-Gagné, Bolduc, Marilène, Savard, Pierre, Leclerc, Denis
Additional file 2: Figure S2. Effect of peptide concentrations on the SrtA coupling reaction. (A) Comparison of the C-terminal sequence of PapMV WT, PapMV-SrtA and PapMV-SrtA(short). In PapMV-SrtA, a linker of 5 amino acids (TSTTR) was added before t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4391749092c60d784329345d860ede46
Publikováno v:
The Journal of biological chemistry. 292(8)
c-Myc-interacting zinc finger protein-1 (Miz-1) is a poly-Cys2His2 zinc finger (ZF) transcriptional regulator of many cell cycle genes. A Miz-1 DNA sequence consensus has recently been identified and has also unveiled Miz-1 functions in other cellula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8d892c7ba44e6a9dd7835b69112efa2
https://pubmed.ncbi.nlm.nih.gov/28035002
https://pubmed.ncbi.nlm.nih.gov/28035002
Publikováno v:
Proteins. 85(2)
c-Myc is a basic helix-loop-helix leucine zipper (b-HLH-LZ) transcription factor deregulated in the majority of human cancers. As a heterodimer with Max, another b-HLH-LZ transcription factor, deregulated and persistent c-Myc accumulates at transcrip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ac34ee0a4a1b0c6fea62843bc5a31a3d
https://pubmed.ncbi.nlm.nih.gov/27859590
https://pubmed.ncbi.nlm.nih.gov/27859590