Distinction of clenbuterol intake from drug or contaminated food of animal origin in a controlled administration trial – the potential of enantiomeric separation for doping control analysis

Autor: Thijs Meijer, Franz Liebetrau, Dorota Kwiatkowska, Maria Kristina Parr, Emilia Waraksa, Mijo Stanic, Marco Blokland, Alexander H. Schmidt, Saskia S. Sterk

Publikováno v: Food Additives & Contaminants. Pt. A, Chemistry, Analysis, Control, Exposure & Risk Assessment, 34(4), 525-535
Food Additives & Contaminants. Pt. A, Chemistry, Analysis, Control, Exposure & Risk Assessment 34 (2017) 4

The differentiation of clenbuterol abuse and unintentional ingestion from contaminated meat is crucial with respect to the valuation of an adverse analytical finding in human sports doping control. The proportion of the two enantiomers of clenbuterol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::814a88361376db71d5505c83bb4d7380
https://doi.org/10.1080/19440049.2016.1242169

SFC-MS/MS as an orthogonal technique for improved screening of polar analytes in anti-doping control

Autor: Maxi Wenzel, Mijo Stanic, Francesco Botrè, Maria Kristina Parr, Edgar Naegele, Jan Felix Joseph, Xavier de la Torre, Bernhard Wuest, Alexander H. Schmidt

Publikováno v: Analytical and bioanalytical chemistry. 408(24)

HPLC is considered the method of choice for the separation of various classes of drugs. However, some analytes are still challenging as HPLC shows limited resolution capabilities for highly polar analytes as they interact insufficiently on convention

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03774f3c7921010476c622601a55723b
https://pubmed.ncbi.nlm.nih.gov/27553949