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Akademický článek

Comparison of pharmacogenomic information for drug approvals provided by the national regulatory agencies in Korea, Europe, Japan, and the United States

Autor: Mijin Lee, Ji Min Han, Jaeyeon Lee, Ju Young Oh, Jung Sun Kim, Hye Sun Gwak, Kyung Hee Choi

Publikováno v: Frontiers in Pharmacology, Vol 14 (2023)

Pharmacogenomics, which is defined as the study of changes in the properties of DNA and RNA associated with drug response, enables the prediction of the efficacy and adverse effects of drugs based on patients’ specific genetic mutations. For the sa

Externí odkaz: https://doaj.org/article/e059997b39d841cda41c5003cc87f144

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Akademický článek

Vitamin B12 Supplementation Improves Oocyte Development by Modulating Mitochondria and Yolk Protein in a Caffeine-Ingested Caenorhabditis elegans Model

Autor: Hyemin Min, Mijin Lee, Sangwon Kang, Yhong-Hee Shim

Publikováno v: Antioxidants, Vol 13, Iss 1, p 53 (2023)

Vitamin B12 is an essential cofactor involved in the function of two enzymes: cytosolic methionine synthase and mitochondrial methylmalonic-CoA mutase. In our previous studies, caffeine (1,3,7-trimethylxanthine), the most popular bioactivator, was sh

Externí odkaz: https://doaj.org/article/3b3237cea26c4cb89848f831944a8323

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Akademický článek

3,3′-Diindolylmethane Supplementation Maintains Oocyte Quality by Reducing Oxidative Stress and CEP-1/p53-Mediated Regulation of Germ Cells in a Reproductively Aged Caenorhabditis elegans Model

Autor: Mijin Lee, Esther Youn, Kyungsu Kang, Yhong-Hee Shim

Publikováno v: Antioxidants, Vol 11, Iss 5, p 950 (2022)

In recent decades, maternal age at first birth has increased, as has the risk of infertility due to rapidly declining oocyte quality with age. Therefore, an understanding of female reproductive aging and the development of potential modulators to con

Externí odkaz: https://doaj.org/article/ab3c01bdaf48436581d298f3eeb71198

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Akademický článek

Nicotinamide Supplementation Improves Oocyte Quality and Offspring Development by Modulating Mitochondrial Function in an Aged Caenorhabditis elegans Model

Autor: Hyemin Min, Mijin Lee, Kyoung Sang Cho, Hyunjung Jade Lim, Yhong-Hee Shim

Publikováno v: Antioxidants, Vol 10, Iss 4, p 519 (2021)

Aging is associated with a decline in the quality of biological functions. Among the aging processes, reproductive aging is a critical process because of its intergenerational effects. However, the mechanisms underlying reproductive aging remain larg

Externí odkaz: https://doaj.org/article/0b2f6062e1e74451b649a8b3706192cd

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Akademický článek

A Review of Brain-Computer Interface Games and an Opinion Survey from Researchers, Developers and Users

Autor: Minkyu Ahn, Mijin Lee, Jinyoung Choi, Sung Chan Jun

Publikováno v: Sensors, Vol 14, Iss 8, Pp 14601-14633 (2014)

In recent years, research on Brain-Computer Interface (BCI) technology for healthy users has attracted considerable interest, and BCI games are especially popular. This study reviews the current status of, and describes future directions, in the fiel

Externí odkaz: https://doaj.org/article/742b32c7ec1f43d296622da9cf4bf034

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