Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Mija Ahn"'
Autor:
Ganipisetti Srinivasrao, Jung-Eun Park, Sungmin Kim, Mija Ahn, Chaejoon Cheong, Ky-Youb Nam, Pethaiah Gunasekaran, Eunha Hwang, Nam-Hyung Kim, Song Yub Shin, Kyung S Lee, Eunkyung Ryu, Jeong Kyu Bang
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107432 (2014)
Polo-like kinase-1 (Plk1) plays a crucial role in cell proliferation and the inhibition of Plk1 has been considered as a potential target for specific inhibitory drugs in anti-cancer therapy. Several research groups have identified peptide-based inhi
Externí odkaz:
https://doaj.org/article/6502c90b36834e9e8407e0cb83604792
Autor:
Ravichandran N Murugan, Mija Ahn, Woo Cheol Lee, Hye-Yeon Kim, Jung Hyun Song, Chaejoon Cheong, Eunha Hwang, Ji-Hyung Seo, Song Yub Shin, Sun Ho Choi, Jung-Eun Park, Jeong Kyu Bang
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e80043 (2013)
BACKGROUND: Over the years, a great deal of effort has been focused on the design and synthesis of potent, linear peptide inhibitors targeting the polo-like kinase 1 (Plk1), which is critically involved in multiple mitotic processes and has been esta
Externí odkaz:
https://doaj.org/article/1449daaa999240f594f033e6bd3bdfa2
Autor:
Ravichandran N Murugan, Binu Jacob, Mija Ahn, Eunha Hwang, Hoik Sohn, Hyo-Nam Park, Eunjung Lee, Ji-Hyung Seo, Chaejoon Cheong, Ky-Youb Nam, Jae-Kyung Hyun, Ki-Woong Jeong, Yangmee Kim, Song Yub Shin, Jeong Kyu Bang
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e80025 (2013)
BACKGROUND: Much attention has been focused on the design and synthesis of potent, cationic antimicrobial peptides (AMPs) that possess both antimicrobial and anti-inflammatory activities. However, their development into therapeutic agents has been li
Externí odkaz:
https://doaj.org/article/f3a8b3ccce4f4534a7014ee4372678ec
Autor:
Young-Ho Chung, Nak-Kyun Soung, Minkyoung Kim, Joonhyeok Choi, Young-Ho Lee, Kyeong-Ryoon Lee, Eunice EunKyeong Kim, Min Ju Kim, Young-Ho Jeon, Kyeong Lee, Mija Ahn, Eun Kyoung Ryu, Kyung S. Lee, Geul Bang, Pethaiah Gunasekaran, Jung-Eun Park, Min Su Yim, Jaehi Kim, Sang Chul Shin, Bo Yeon Kim, Jeong Kyu Bang, Hak Nam Kim
Publikováno v:
J Med Chem
Polo-like kinase-1 (Plk1) plays a key role in mitosis and has been identified as an attractive anticancer drug target. Plk1 consists of two drug-targeting sites, namely, N-terminal kinase domain (KD) and C-terminal polo-box domain (PBD). As KD-target
Autor:
Kun Cho, Jeong Kyu Bang, Eun Young Kim, Geul Bang, Pethaiah Gunasekaran, Soo-Jae Lee, Nam-Hyung Kim, Young Ho Jeon, Ganesan Rajasekaran, Eun Kyoung Ryu, Mija Ahn, Hyun-Ju Lee, Song Yub Shin, Jae-Kyung Hyun
Publikováno v:
European Journal of Medicinal Chemistry. 125:551-564
In this study, we report on the first chemical synthesis of ultra-short pyrazole-arginine based antimicrobial peptidomimetics derived from the newly synthesized N-alkyl/aryl pyrazole amino acids. Through the systematic tuning of hydrophobicity, charg
Autor:
Mija Ahn1, Ganesan Rajasekaran2, Gunasekaran P.3, Eun kyoung Ryu1, Ga-hyang Lee4, Jae-Kyung Hyun5, Chaejoon Cheong1, Nam-Hyung Kim3, Song Yub Shin2 syshin@chosun.ac.kr, Jeong-Kyu Bang1 bangjk@kbsi.re.kr
Publikováno v:
Bulletin of the Korean Chemical Society. 2014, Vol. 35 Issue 9, p2818-2824. 7p.
Autor:
Eun Hee Han, Woo-Young Bang, Seon-Mi Jin, Mija Ahn, Eunji Lee, Eunhee Ko, Jeong Kyu Bang, Inhye Kim
Publikováno v:
Biomacromolecules. 18(11)
Gadolinium (Gd[III])-based nanoaggregates are potential noninvasive magnetic resonance imaging (MRI) probes with excellent spatial and temporal resolution for cancer diagnosis. Peptides conjugated with Gd3+ can aid in supramolecular scaffolding for M
Autor:
Seung-Min Jeong, Ki-Yub Nam, Toshiki Takei, Nam-Hyung Kim, Hak Nam Kim, Hironobu Hojo, So-Rim Lee, Jeong Kyu Bang, Yuya Asahina, Jeongwoo Kwon, Mija Ahn, Suk Namgoong, Eun Kyung Ryu, Seongnyeon Kim, Geul Bang, Song Yub Shin, Pethaiah Gunasekaran
Publikováno v:
ChemMedChem. 12(8)
Polo-like kinase 1 (PLK1) plays crucial roles in various stages of oocyte maturation. Recently, we reported that the peptidomimetic compound AB103-8, which targets the polo box domain (PBD) of PLK1, affects oocyte meiotic maturation and the resumptio
Autor:
Nam-Hyung Kim, Mija Ahn, Song Yub Shin, Jeong-Kyu Bang, Pethaiah Gunasekaran, Ganesan Rajasekaran, Jae-Kyung Hyun, Ga-hyang Lee, Chaejoon Cheong, Eun Kyoung Ryu
Publikováno v:
Bulletin of the Korean Chemical Society. 35:2818-2824
Division of Magnetic Resonance, Korea Basic Science Institute,Chungbuk 363-883, Korea. E-mail: bangjk@kbsi.re.kr Department of Bio-Materials, Graduate School and Department of Cellular & Molecular Medicine, School of Medicine, Chosun University, Gwan
Autor:
Kyung S. Lee, Shinobu Komiya, Mija Ahn, Nam Kim, Bonsu Ku, Tae Sung Kim, Suk Youl Park, Seung Jun Kim, Jung-Eun Park, Ju Hee Kim, Jeong K. Bang, Ki Won Lee, Byung-Ha Oh, Wei Yang, Lan Tian, Raymond L. Erikson, Bo Yeon Kim, Mi Jeong Kwak, Hironobu Hojo, Ravichandran N. Murugan
Publikováno v:
Nature structural & molecular biology
Polo-like kinase 4 (Plk4) is a key regulator of centriole duplication, an event critical for the maintenance of genomic integrity. Here we showed that Plk4 relocalizes from the inner Cep192 ring to the outer Cep152 ring as newly recruited Cep152 asse