Zobrazeno 1 - 10 of 24 pro vyhledávání: '"Miina K. Öhman"'
2
Akademický článek
In Vivo Generation of Post-infarct Human Cardiac Muscle by Laminin-Promoted Cardiovascular Progenitors
Autor: Lynn Yap, Jiong-Wei Wang, Aida Moreno-Moral, Li Yen Chong, Yi Sun, Nathan Harmston, Xiaoyuan Wang, Suet Yen Chong, Miina K. Öhman, Heming Wei, Ralph Bunte, Sujoy Gosh, Stuart Cook, Outi Hovatta, Dominique P.V. de Kleijn, Enrico Petretto, Karl Tryggvason
Publikováno v: Cell Reports, Vol 26, Iss 12, Pp 3231-3245.e9 (2019)
Summary: Regeneration of injured human heart muscle is limited and an unmet clinical need. There are no methods for the reproducible generation of clinical-quality stem cell-derived cardiovascular progenitors (CVPs). We identified laminin-221 (LN-221
Externí odkaz: https://doaj.org/article/5528036c24444c48b01a49e6d7a417bd
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3
Akademický článek
Membrane‐Tethered Metalloproteinase Expressed by Vascular Smooth Muscle Cells Limits the Progression of Proliferative Atherosclerotic Lesions
Autor: Richard H. Barnes, Takeshi Akama, Miina K. Öhman, Moon‐Sook Woo, Julian Bahr, Stephen J. Weiss, Daniel T. Eitzman, Tae‐Hwa Chun
Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 6, Iss 7 (2017)
BackgroundThe MMP (matrix metalloproteinase) family plays diverse and critical roles in directing vascular wall remodeling in atherosclerosis. Unlike secreted‐type MMPs, a member of the membrane‐type MMP family, MT1‐MMP (membrane‐type 1 MMP;
Externí odkaz: https://doaj.org/article/63d86c072b494c0f92dd691b76fcbf1d
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6
Culturing functional pancreatic islets on α5-laminins and curative transplantation to diabetic mice
Autor: Benjamin L. George, Yang Sun, Enrico Petretto, Anne-May Österholm, Xiaoran Chai, Miina K. Öhman, Kristmundur Sigmundsson, Molly M. Stevens, Manuel Patarroyo, Anna Domogatskaya, Ann-Sofie Nilsson, Aida Moreno-Moral, Li Yen Chong, Juha R.M. Ojala, Karl Tryggvason, Joseph A. M. Steele, Sergey Rodin, Sujoy Ghosh
Publikováno v: Matrix biology : journal of the International Society for Matrix Biology. 70
The efficacy of islet transplantation for diabetes treatment suffers from lack of cadaver-derived islets, islet necrosis and long transfer times prior to transplantation. Here, we developed a method for culturing mouse and human islets in vitro on α
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de30e207cc1ae1404f3a8bd048a9f67a
https://pubmed.ncbi.nlm.nih.gov/29601863
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7
Membrane‐Tethered Metalloproteinase Expressed by Vascular Smooth Muscle Cells Limits the Progression of Proliferative Atherosclerotic Lesions
Autor: Daniel T. Eitzman, Takeshi Akama, Richard H. Barnes, Julian C. Bahr, Miina K. Öhman, Stephen J. Weiss, Tae Hwa Chun, Moon Sook Woo
Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background The MMP (matrix metalloproteinase) family plays diverse and critical roles in directing vascular wall remodeling in atherosclerosis. Unlike secreted‐type MMP s, a member of the membrane‐type MMP family, MT 1‐ MMP (membrane‐type 1 M
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c1c8a125794c968dd02956947a7eabc
http://europepmc.org/articles/PMC5586255
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8
CerS2 Haploinsufficiency Inhibits β-Oxidation and Confers Susceptibility to Diet-Induced Steatohepatitis and Insulin Resistance
Autor: Suryaprakash, Raichur, Siew Tein, Wang, Puck Wee, Chan, Ying, Li, Jianhong, Ching, Bhagirath, Chaurasia, Bghagirath, Chaurasia, Shaillay, Dogra, Miina K, Öhman, Kosuke, Takeda, Shigeki, Sugii, Yael, Pewzner-Jung, Anthony H, Futerman, Scott A, Summers
Publikováno v: Cell Metabolism. 20(4):687-695
Summary Inhibition of ceramide synthesis prevents diabetes, steatosis, and cardiovascular disease in rodents. Six different ceramide synthases (CerS) that differ in tissue distribution and substrate specificity account for the diversity in acyl-chain
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fceef30f850ed3d8ccca37166302d31
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9
In Vivo Generation of Post-infarct Human Cardiac Muscle by Laminin-Promoted Cardiovascular Progenitors
Autor: Xiaoyuan Wang, Sujoy Gosh, Miina K. Öhman, Suet Yen Chong, Heming Wei, Li Yen Chong, Yi Sun, Ralph M. Bunte, Lynn Yap, Enrico Petretto, Dominique P.V. de Kleijn, Konstantinos Vanezis, Stuart A. Cook, Jiong-Wei Wang, Outi Hovatta, Nathan Harmston, Aida Moreno-Moral, Karl Tryggvason
Publikováno v: Cell Reports, Vol 26, Iss 12, Pp 3231-3245.e9 (2019)
Cell Reports, Vol 31, Iss 8, Pp-(2020)
Summary: Regeneration of injured human heart muscle is limited and an unmet clinical need. There are no methods for the reproducible generation of clinical-quality stem cell-derived cardiovascular progenitors (CVPs). We identified laminin-221 (LN-221
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b5974b3942943ebc277fda1563ce505
https://doi.org/10.1016/j.celrep.2019.02.083
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10
P-selectin glycoprotein ligand-1 deficiency leads to cytokine resistance and protection against atherosclerosis in apolipoprotein E deficient mice
Autor: Hui Wang, Julia Wang, Wei Luo, Miina K. Öhman, Daniel T. Eitzman, Chiao Guo, Kate Shi
Publikováno v: Atherosclerosis. 220:110-117
Adhesive interactions between endothelial cells and leukocytes contribute to atherosclerotic plaque growth. However, mechanism(s) responsible for endothelial priming and deactivation in inflammatory diseases such as atherosclerosis are not clear. Apo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7eb92584c4496477b0927d73d47df1c6
https://doi.org/10.1016/j.atherosclerosis.2011.10.012
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